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The map label for this gene is nagA [H]

Identifier: 209694409

GI number: 209694409

Start: 924571

End: 925707

Strand: Reverse

Name: nagA [H]

Synonym: VSAL_I0830

Alternate gene names: 209694409

Gene position: 925707-924571 (Counterclockwise)

Preceding gene: 209694412

Following gene: 209694408

Centisome position: 27.84

GC content: 39.49

Gene sequence:

>1137_bases
ATGTATGCGCTAACTAACTGTAAAGTCTATACTGGTAATGATGTTCTTGTTGATCACTCAGTGATTATCAACGGCACCAA
TATTGAAAAAATCTGCCTAACATCTGAACTTCCTGATGGCATCGAACGTAAAGATTTAGACGGTGCTAATTTAAGCCCTG
GTTTCATCGACCTTCAGCTAAATGGCTGTGGTGGTGTAATGCTAAATGATGAAATTACAGCAAAAACCATGCAAATAATG
CATGAAGCAAACCTTAAATCAGGTTGTACTAGCTTTTTACCTACATTAATCACTTCTTCAGACGAAGATATGCGCGCTTC
TATTGAAGCTGCTCGTGAATATCACAATAAATATCAAAACCAATCTTTAGGTTTACACCTTGAAGGTCCGTACCTAAATG
TCATGAAAAAAGGCATTCACAGCGTTGATCATATCCGTCACTCAGATTCAGATATGATCCAACTTATGTGTGATAACGCT
GATTTAATCACCAAAGTGACATTGGCTCCTGAGCAAAATGATCCTGAACATATTGAGCGTCTTCACAAGGCTGGTATTGT
TGTTTCAATTGGCCACACAAACGCAACGTATGCTGAAGCTCGGCAAGGTTTTGAGTCAGGCATTACATTCGCTACTCATT
TATTTAATGCAATGACACCAATGGTAGGTCGCGAACCAGGTGTTGTTGGTGCCATCTACGATACACCAGACGTTTATGCT
GGCATTATCGCTGATGGCTTCCATGTTGATTACGCAAACATTCGTATCGCGCACAAAATAAAGAAAGAAAAGTTAGTATT
AGTGACCGATGCCACAGCTCCTGCAGGTGCTGACATGGAATACTTTATTTTTGTGGGGAAGAAAGTATATTACAAGGATG
GTAAATGTGTTGATGAAAATGGCACATTAGGTGGCTCAGCTCTGACTATGATTGAAGCAGTTCAGAATACAGTTGAACAC
GTTGGAATCGCTTTAGATGAAGCTCTACGTATGGCTACGTTATATCCTGCTCAAGCAATTGGTGTAGATAATAAACTTGG
TCGAATCAAAAAAGACATGGTAGCTAACCTTGCTATTTTTGATCGTGACTTTAATGTAAAAGCGACTGTTGTTAACGGAC
AATACGAGCAAAGTTAA

Upstream 100 bases:

>100_bases
CCGCTCAGTAAGCAGTTTTATTTTTTACTTGCTTAAAAATTTCCACAAAAAAAGTTCTATTTTTTTTGTATACTAAATTA
TAACTTAAAGGATTCACGCT

Downstream 100 bases:

>100_bases
TATGACTGACGGACAAATTGGTAATGTAGATCTAGTAAAACAATTAAACAGTGCCGCTGTTTATCGTTTAATCGACCAAA
AAGGACCGATTTCTCGAATT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MYALTNCKVYTGNDVLVDHSVIINGTNIEKICLTSELPDGIERKDLDGANLSPGFIDLQLNGCGGVMLNDEITAKTMQIM
HEANLKSGCTSFLPTLITSSDEDMRASIEAAREYHNKYQNQSLGLHLEGPYLNVMKKGIHSVDHIRHSDSDMIQLMCDNA
DLITKVTLAPEQNDPEHIERLHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDENGTLGGSALTMIEAVQNTVEH
VGIALDEALRMATLYPAQAIGVDNKLGRIKKDMVANLAIFDRDFNVKATVVNGQYEQS

Sequences:

>Translated_378_residues
MYALTNCKVYTGNDVLVDHSVIINGTNIEKICLTSELPDGIERKDLDGANLSPGFIDLQLNGCGGVMLNDEITAKTMQIM
HEANLKSGCTSFLPTLITSSDEDMRASIEAAREYHNKYQNQSLGLHLEGPYLNVMKKGIHSVDHIRHSDSDMIQLMCDNA
DLITKVTLAPEQNDPEHIERLHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDENGTLGGSALTMIEAVQNTVEH
VGIALDEALRMATLYPAQAIGVDNKLGRIKKDMVANLAIFDRDFNVKATVVNGQYEQS
>Mature_378_residues
MYALTNCKVYTGNDVLVDHSVIINGTNIEKICLTSELPDGIERKDLDGANLSPGFIDLQLNGCGGVMLNDEITAKTMQIM
HEANLKSGCTSFLPTLITSSDEDMRASIEAAREYHNKYQNQSLGLHLEGPYLNVMKKGIHSVDHIRHSDSDMIQLMCDNA
DLITKVTLAPEQNDPEHIERLHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDENGTLGGSALTMIEAVQNTVEH
VGIALDEALRMATLYPAQAIGVDNKLGRIKKDMVANLAIFDRDFNVKATVVNGQYEQS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI224922791, Length=417, Percent_Identity=31.89448441247, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI21361513, Length=418, Percent_Identity=31.5789473684211, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1786892, Length=376, Percent_Identity=59.5744680851064, Blast_Score=471, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17553768, Length=387, Percent_Identity=31.0077519379845, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI19920392, Length=387, Percent_Identity=32.8165374677003, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=31.4214463840399, Blast_Score=162, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41310; Mature: 41310

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALTNCKVYTGNDVLVDHSVIINGTNIEKICLTSELPDGIERKDLDGANLSPGFIDLQL
CEEEEEEEEEECCEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEE
NGCGGVMLNDEITAKTMQIMHEANLKSGCTSFLPTLITSSDEDMRASIEAAREYHNKYQN
CCCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QSLGLHLEGPYLNVMKKGIHSVDHIRHSDSDMIQLMCDNADLITKVTLAPEQNDPEHIER
CCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHH
LHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
HHHCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDEN
HHEECCEEEEEEEEEEEEEECCCEEEEEEECCCCCCCCEEEEEEECCEEEECCCEEECCC
GTLGGSALTMIEAVQNTVEHVGIALDEALRMATLYPAQAIGVDNKLGRIKKDMVANLAIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHEEEEE
DRDFNVKATVVNGQYEQS
ECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MYALTNCKVYTGNDVLVDHSVIINGTNIEKICLTSELPDGIERKDLDGANLSPGFIDLQL
CEEEEEEEEEECCEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEE
NGCGGVMLNDEITAKTMQIMHEANLKSGCTSFLPTLITSSDEDMRASIEAAREYHNKYQN
CCCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QSLGLHLEGPYLNVMKKGIHSVDHIRHSDSDMIQLMCDNADLITKVTLAPEQNDPEHIER
CCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHH
LHKAGIVVSIGHTNATYAEARQGFESGITFATHLFNAMTPMVGREPGVVGAIYDTPDVYA
HHHCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
GIIADGFHVDYANIRIAHKIKKEKLVLVTDATAPAGADMEYFIFVGKKVYYKDGKCVDEN
HHEECCEEEEEEEEEEEEEECCCEEEEEEECCCCCCCCEEEEEEECCEEEECCCEEECCC
GTLGGSALTMIEAVQNTVEHVGIALDEALRMATLYPAQAIGVDNKLGRIKKDMVANLAIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHEEEEE
DRDFNVKATVVNGQYEQS
ECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]