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The map label for this gene is ybbO [H]

Identifier: 209694387

GI number: 209694387

Start: 894931

End: 895758

Strand: Reverse

Name: ybbO [H]

Synonym: VSAL_I0805

Alternate gene names: 209694387

Gene position: 895758-894931 (Counterclockwise)

Preceding gene: 209694388

Following gene: 209694386

Centisome position: 26.94

GC content: 38.65

Gene sequence:

>828_bases
ATGCAACGCGCTATTTTTATCACTGGTTGTTCAACTGGCATTGGTTACACCACCGCTCATCAACTCTCAAAACATGGTTT
TCATGTCATTGCTTCATGCCGTAAAAAAGAAGACGTTTTACGATTGCAAAATGAAGGATTAACGTGCTTACACTTAGATT
ATTCGGACTCAGAGAGCATTTCTCTGGCGGTCAGCGAGTTATTAGCACTTACTGATGGAAAGTTGTACGCTTTATTCAAT
AATGGCGCGTATGGACAAGCGGGTGCACTGGAAGATCTGCCTAGAGAGGCACTAAAAGAGCAGTTTGAAGCAAACTTCTT
TGGTTGGCATCAGTTAGTAATAGAGTTACTACCAATAATGAGAAAGCAAGGCTATGGAAGGATCATACAAAACAGCTCAG
TACTTGGCATTGTGGCGATGAAATACCGTGGTGCATACAATTCTTCAAAATTCGCAATTGAAGGTTGGAGCGATACATTA
CGTTTAGAGTTAATGCAGACTAATATCCAGATCAGTTTAATTGAACCCGGTCCTATCGAGACAAACTTTAGATCTAATGC
ATTGAAAGCATTTAAAAAATGGGTAACTATCGAGAATAGTCCACATAAAGAAAAATACCTTATGCAACAACAGCGGTTAG
AGAAAGAAGCCTCCGGAAGTGCCTTTGTACTCCCTCCTGAATCGATTATGTCACCATTGCTTCATGCACTTAATAGCAAA
AAACCTAAAGCACGATATAGAGTTACCTTTCCTACTCATTTATTTGCAATATTAAAACGATTATTACCAACTAAGTGGTT
AGATATGATCTTAAATAAGAGTGACTAA

Upstream 100 bases:

>100_bases
CGTCATTTTGACGTCATTATTTTCTTTCTTAGTTTGGTTTTTATCGACTTACATGGGTAGTTACATCAGTAATTATCCAT
TCATGCAAAGGAAGCAATGA

Downstream 100 bases:

>100_bases
TGTCATATTTTAAGTTTGTTTCAACCAAATAGAGAAGAAATATAAAAAAAGAACAATAATGTAATATTAGTGTCACATTG
CAAGATTATATTTATTCCTA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MQRAIFITGCSTGIGYTTAHQLSKHGFHVIASCRKKEDVLRLQNEGLTCLHLDYSDSESISLAVSELLALTDGKLYALFN
NGAYGQAGALEDLPREALKEQFEANFFGWHQLVIELLPIMRKQGYGRIIQNSSVLGIVAMKYRGAYNSSKFAIEGWSDTL
RLELMQTNIQISLIEPGPIETNFRSNALKAFKKWVTIENSPHKEKYLMQQQRLEKEASGSAFVLPPESIMSPLLHALNSK
KPKARYRVTFPTHLFAILKRLLPTKWLDMILNKSD

Sequences:

>Translated_275_residues
MQRAIFITGCSTGIGYTTAHQLSKHGFHVIASCRKKEDVLRLQNEGLTCLHLDYSDSESISLAVSELLALTDGKLYALFN
NGAYGQAGALEDLPREALKEQFEANFFGWHQLVIELLPIMRKQGYGRIIQNSSVLGIVAMKYRGAYNSSKFAIEGWSDTL
RLELMQTNIQISLIEPGPIETNFRSNALKAFKKWVTIENSPHKEKYLMQQQRLEKEASGSAFVLPPESIMSPLLHALNSK
KPKARYRVTFPTHLFAILKRLLPTKWLDMILNKSD
>Mature_275_residues
MQRAIFITGCSTGIGYTTAHQLSKHGFHVIASCRKKEDVLRLQNEGLTCLHLDYSDSESISLAVSELLALTDGKLYALFN
NGAYGQAGALEDLPREALKEQFEANFFGWHQLVIELLPIMRKQGYGRIIQNSSVLGIVAMKYRGAYNSSKFAIEGWSDTL
RLELMQTNIQISLIEPGPIETNFRSNALKAFKKWVTIENSPHKEKYLMQQQRLEKEASGSAFVLPPESIMSPLLHALNSK
KPKARYRVTFPTHLFAILKRLLPTKWLDMILNKSD

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=258, Percent_Identity=32.1705426356589, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI223718074, Length=272, Percent_Identity=30.8823529411765, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI40548397, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI214010158, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI214010156, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI22758144, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI19743808, Length=289, Percent_Identity=30.4498269896194, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI22507405, Length=286, Percent_Identity=29.7202797202797, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI150247226, Length=285, Percent_Identity=29.4736842105263, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI50726952, Length=286, Percent_Identity=30.0699300699301, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI44680136, Length=264, Percent_Identity=25.7575757575758, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI44680133, Length=264, Percent_Identity=25.7575757575758, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI17738292, Length=264, Percent_Identity=25.7575757575758, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=31.1224489795918, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=30.8080808080808, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4504503, Length=293, Percent_Identity=28.3276450511945, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI119392083, Length=205, Percent_Identity=31.7073170731707, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32455239, Length=214, Percent_Identity=28.9719626168224, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031765, Length=214, Percent_Identity=28.9719626168224, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=191, Percent_Identity=28.2722513089005, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=191, Percent_Identity=29.8429319371728, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786701, Length=271, Percent_Identity=43.9114391143911, Blast_Score=242, Evalue=2e-65,
Organism=Escherichia coli, GI87082100, Length=182, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787335, Length=184, Percent_Identity=27.7173913043478, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=282, Percent_Identity=26.9503546099291, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193210355, Length=273, Percent_Identity=28.9377289377289, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=216, Percent_Identity=31.0185185185185, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17570069, Length=214, Percent_Identity=29.4392523364486, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17557780, Length=288, Percent_Identity=25, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17507613, Length=288, Percent_Identity=24.3055555555556, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32563809, Length=288, Percent_Identity=24.3055555555556, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=28.9795918367347, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=250, Percent_Identity=27.6, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=32.6530612244898, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651139, Length=296, Percent_Identity=30.0675675675676, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580925, Length=201, Percent_Identity=25.8706467661692, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571526, Length=189, Percent_Identity=28.042328042328, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31073; Mature: 31073

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRAIFITGCSTGIGYTTAHQLSKHGFHVIASCRKKEDVLRLQNEGLTCLHLDYSDSESI
CCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
SLAVSELLALTDGKLYALFNNGAYGQAGALEDLPREALKEQFEANFFGWHQLVIELLPIM
HHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RKQGYGRIIQNSSVLGIVAMKYRGAYNSSKFAIEGWSDTLRLELMQTNIQISLIEPGPIE
HHCCCCEEECCCCEEEEEEEEECCCCCCCCEEEECCCCCEEEEEEECCEEEEEECCCCCC
TNFRSNALKAFKKWVTIENSPHKEKYLMQQQRLEKEASGSAFVLPPESIMSPLLHALNSK
CCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCC
KPKARYRVTFPTHLFAILKRLLPTKWLDMILNKSD
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQRAIFITGCSTGIGYTTAHQLSKHGFHVIASCRKKEDVLRLQNEGLTCLHLDYSDSESI
CCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
SLAVSELLALTDGKLYALFNNGAYGQAGALEDLPREALKEQFEANFFGWHQLVIELLPIM
HHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RKQGYGRIIQNSSVLGIVAMKYRGAYNSSKFAIEGWSDTLRLELMQTNIQISLIEPGPIE
HHCCCCEEECCCCEEEEEEEEECCCCCCCCEEEECCCCCEEEEEEECCEEEEEECCCCCC
TNFRSNALKAFKKWVTIENSPHKEKYLMQQQRLEKEASGSAFVLPPESIMSPLLHALNSK
CCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCC
KPKARYRVTFPTHLFAILKRLLPTKWLDMILNKSD
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]