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The map label for this gene is hlyB [H]

Identifier: 209694381

GI number: 209694381

Start: 885635

End: 887509

Strand: Reverse

Name: hlyB [H]

Synonym: VSAL_I0799

Alternate gene names: 209694381

Gene position: 887509-885635 (Counterclockwise)

Preceding gene: 209694383

Following gene: 209694380

Centisome position: 26.69

GC content: 40.75

Gene sequence:

>1875_bases
ATGAAATTAAAACATAAATTAATCGGGGCCAGTCTACTTGCTGTTATCGTGACGGCTGCTGCATTAACATGGCTCGCGTC
AAATCAGTTGTTTGAACAAACTCGAAATGGCGTTTATTCTCGAGCTGAAAGTGTGACATCTTCTGCCACTACCGGAATTT
CTAATTGGATTTCAATTAAAGCTGAAATTGCGCATGCTATTAATGACTACACTCAAGAAGATGACGTGGTCTCTTTTTTA
CAGTTAAGCCGTAAAGCGGGTGGTTTTGATAATATTTTCTTTGGTACACCTCAAGGGGATATGTACCGCTCTCATCCTGA
AAGAAATCGTGCCGATTACGATCCTCGTCAACGCCCTTGGTATCAAGAAGCTCAACGAGAAAACAAACAAATCATTACTT
CCGCCTATCAAGATGCCATTACTCAATCTCTTCTGGTAACCATTGCTGAACCTGTTTATAAGAATGGTCAATTTCTTGGT
GTTGTCGGTGCCGATGTACTAATTGATCAACTAATTGACGATGTCATCAGCCTAGATGCAGGTAAAGACACCATCACAAT
GTTAATTGATAGCGATGGCACTTTCTTAACGCATCCAAATACGTCGCTTATCAAAAAAGAAGTAAATCGTTATTTCTCGG
GTATGACGCCTCAAAGTATTCAAGAATCCATTAATTCAAAAACCATTGAATTCGCAGAAATCAACGGCAGTAATAAGCTG
GTTTATTTTGCAAAAGTACCTAATACAAAATGGACATTTGCCGTTGAAATGACACAAGCAACAGAAGAAGCCGCACACAG
CGCACTCCTTCGTGAAATCATCCTGCTTAGCATTGTATTAACAGTCATTGTTGTTATCGGTGTAACCACCTTGGTTAACG
TCCTATTTAGAGATCTACTTCGAGTATCTGATGCGCTTGCTGAAATTTCATCAGGTGAAGGGGATTTAACTCAACGTTTA
ATTCCAAACAGTAATGATGAAGTTGGCCAACTTGCTATCAACTTCAATACCTTTGTGGGCAATATGCACTCAATGGTGTG
TCGCTTACGTGACATATCACTTACGTTAGCTAACCAAGCCAATTTAACCGCAGAAAGTGCTGAAGAACGTAATGTTCGAA
TCCAACATCAAATGGATGAGATCAACATGGTTGCAACCGCAATTAATGAAATGGCAGCTGCGACTCAAGAAATTGCAAGC
AACGCAGATAATACAGCTCAAACAGCTGAACAAACCGTTAGTGCTTCAAACCATGGTGCTGAGCAAGTAAGTCAAAGCCA
ACATTCAATTGATAACTTGGCAAAAGAAGTAGAAACCGCAACACAAGTTATCGGCGAATTGCATCACAACGCACAAAACA
TCAATACGATCCTATCCACCATTCAAAACATTGCAGAACAAACGAACTTACTCGCACTCAATGCCGCAATTGAAGCGGCA
CGTGCCGGTGAACAAGGTCGTGGTTTTGCCGTTGTTGCTGATGAAGTTCGAATTTTAAGTCAACGTACACACGCGTCGAC
TCAAGAAATTCAACAAATGATAGAGACATTGCAAGGCACAACTCAAAAAGCGGTTGGCATCATGGAAGACAGCCAAAATC
TAGCCAACACCAGTGTTGAAGATGCACAATCAGCCTCTGCTAGTTTGCTTCAGATTACAAATTCAGTGACATTAATTAGC
GACATGGCGGCTCAAATTGCAGCGGCGGCTGAAGAGCAATCATCGGTTACAGAAGAAATTACGCGTAACACCGAAGCGGT
TCGTGATGTATCAAATGAATTAACGACCGAAACACAGCAATCGGTTATTCAAGCATCACAATTATCTGAATTATCAAACG
AACTAAAACAAGAAATAGACAGATTTAAACTGTAA

Upstream 100 bases:

>100_bases
GTTATTTCATTTTTGCCCGATACCATATACATAAATGTACAAATAGATAATAAAAATAGAAATTTAATATATAAAATTTC
ACTACAATTTGGATGATATA

Downstream 100 bases:

>100_bases
CCTCTTACTTACTTCGTCAAAAGACAGAATATATTTTTATATTCTGTCTTTTTTTTTCAGAAAAAACCGATTAATGAACA
GATAAATACCGCACAAAACA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MKLKHKLIGASLLAVIVTAAALTWLASNQLFEQTRNGVYSRAESVTSSATTGISNWISIKAEIAHAINDYTQEDDVVSFL
QLSRKAGGFDNIFFGTPQGDMYRSHPERNRADYDPRQRPWYQEAQRENKQIITSAYQDAITQSLLVTIAEPVYKNGQFLG
VVGADVLIDQLIDDVISLDAGKDTITMLIDSDGTFLTHPNTSLIKKEVNRYFSGMTPQSIQESINSKTIEFAEINGSNKL
VYFAKVPNTKWTFAVEMTQATEEAAHSALLREIILLSIVLTVIVVIGVTTLVNVLFRDLLRVSDALAEISSGEGDLTQRL
IPNSNDEVGQLAINFNTFVGNMHSMVCRLRDISLTLANQANLTAESAEERNVRIQHQMDEINMVATAINEMAAATQEIAS
NADNTAQTAEQTVSASNHGAEQVSQSQHSIDNLAKEVETATQVIGELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVEDAQSASASLLQITNSVTLIS
DMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTTETQQSVIQASQLSELSNELKQEIDRFKL

Sequences:

>Translated_624_residues
MKLKHKLIGASLLAVIVTAAALTWLASNQLFEQTRNGVYSRAESVTSSATTGISNWISIKAEIAHAINDYTQEDDVVSFL
QLSRKAGGFDNIFFGTPQGDMYRSHPERNRADYDPRQRPWYQEAQRENKQIITSAYQDAITQSLLVTIAEPVYKNGQFLG
VVGADVLIDQLIDDVISLDAGKDTITMLIDSDGTFLTHPNTSLIKKEVNRYFSGMTPQSIQESINSKTIEFAEINGSNKL
VYFAKVPNTKWTFAVEMTQATEEAAHSALLREIILLSIVLTVIVVIGVTTLVNVLFRDLLRVSDALAEISSGEGDLTQRL
IPNSNDEVGQLAINFNTFVGNMHSMVCRLRDISLTLANQANLTAESAEERNVRIQHQMDEINMVATAINEMAAATQEIAS
NADNTAQTAEQTVSASNHGAEQVSQSQHSIDNLAKEVETATQVIGELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVEDAQSASASLLQITNSVTLIS
DMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTTETQQSVIQASQLSELSNELKQEIDRFKL
>Mature_624_residues
MKLKHKLIGASLLAVIVTAAALTWLASNQLFEQTRNGVYSRAESVTSSATTGISNWISIKAEIAHAINDYTQEDDVVSFL
QLSRKAGGFDNIFFGTPQGDMYRSHPERNRADYDPRQRPWYQEAQRENKQIITSAYQDAITQSLLVTIAEPVYKNGQFLG
VVGADVLIDQLIDDVISLDAGKDTITMLIDSDGTFLTHPNTSLIKKEVNRYFSGMTPQSIQESINSKTIEFAEINGSNKL
VYFAKVPNTKWTFAVEMTQATEEAAHSALLREIILLSIVLTVIVVIGVTTLVNVLFRDLLRVSDALAEISSGEGDLTQRL
IPNSNDEVGQLAINFNTFVGNMHSMVCRLRDISLTLANQANLTAESAEERNVRIQHQMDEINMVATAINEMAAATQEIAS
NADNTAQTAEQTVSASNHGAEQVSQSQHSIDNLAKEVETATQVIGELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVEDAQSASASLLQITNSVTLIS
DMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTTETQQSVIQASQLSELSNELKQEIDRFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=315, Percent_Identity=31.1111111111111, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788194, Length=252, Percent_Identity=31.3492063492063, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787690, Length=352, Percent_Identity=26.1363636363636, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=29.616724738676, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789453, Length=348, Percent_Identity=28.448275862069, Blast_Score=102, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68183; Mature: 68183

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKHKLIGASLLAVIVTAAALTWLASNQLFEQTRNGVYSRAESVTSSATTGISNWISIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
AEIAHAINDYTQEDDVVSFLQLSRKAGGFDNIFFGTPQGDMYRSHPERNRADYDPRQRPW
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
YQEAQRENKQIITSAYQDAITQSLLVTIAEPVYKNGQFLGVVGADVLIDQLIDDVISLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCC
GKDTITMLIDSDGTFLTHPNTSLIKKEVNRYFSGMTPQSIQESINSKTIEFAEINGSNKL
CCCEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCEE
VYFAKVPNTKWTFAVEMTQATEEAAHSALLREIILLSIVLTVIVVIGVTTLVNVLFRDLL
EEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSDALAEISSGEGDLTQRLIPNSNDEVGQLAINFNTFVGNMHSMVCRLRDISLTLANQA
HHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEECCCC
NLTAESAEERNVRIQHQMDEINMVATAINEMAAATQEIASNADNTAQTAEQTVSASNHGA
CCCHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCH
EQVSQSQHSIDNLAKEVETATQVIGELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHH
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVE
HCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCHH
DAQSASASLLQITNSVTLISDMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTTETQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIQASQLSELSNELKQEIDRFKL
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLKHKLIGASLLAVIVTAAALTWLASNQLFEQTRNGVYSRAESVTSSATTGISNWISIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
AEIAHAINDYTQEDDVVSFLQLSRKAGGFDNIFFGTPQGDMYRSHPERNRADYDPRQRPW
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
YQEAQRENKQIITSAYQDAITQSLLVTIAEPVYKNGQFLGVVGADVLIDQLIDDVISLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCC
GKDTITMLIDSDGTFLTHPNTSLIKKEVNRYFSGMTPQSIQESINSKTIEFAEINGSNKL
CCCEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCEE
VYFAKVPNTKWTFAVEMTQATEEAAHSALLREIILLSIVLTVIVVIGVTTLVNVLFRDLL
EEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSDALAEISSGEGDLTQRLIPNSNDEVGQLAINFNTFVGNMHSMVCRLRDISLTLANQA
HHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHEEECCCC
NLTAESAEERNVRIQHQMDEINMVATAINEMAAATQEIASNADNTAQTAEQTVSASNHGA
CCCHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCH
EQVSQSQHSIDNLAKEVETATQVIGELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHH
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVE
HCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCHH
DAQSASASLLQITNSVTLISDMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTTETQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIQASQLSELSNELKQEIDRFKL
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]