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The map label for this gene is tadA [H]

Identifier: 209694336

GI number: 209694336

Start: 835031

End: 835564

Strand: Direct

Name: tadA [H]

Synonym: VSAL_I0748

Alternate gene names: 209694336

Gene position: 835031-835564 (Clockwise)

Preceding gene: 209694335

Following gene: 209694338

Centisome position: 25.11

GC content: 44.38

Gene sequence:

>534_bases
ATGACAGATTTAGACGAGAATAAGAGCGCGACGTTCTATATGCAAAGAGCGATAGAGCTTGCCTCAATCGCAGAAGGTGA
GGGGGAAGTTCCTGTCGGTGCCGTTATTGTGCTCAATGGCGAGATAATAGGAGAAGGCTGGAACCGTTCAATTGGAACTC
ATGATGCTACCGCTCATGCTGAGATGATGGCGATTAAGCAAGCGGGGCAAACCGTTGAGAACTATCGACTGGTTAACGCG
ACGTTATATGTCACTCTTGAGCCTTGTCCAATGTGTGCTGGCGCCATCGTACAGAGTCGAATTAAACAGGTTTTTTTTGG
TGCTGCGGATTTAAAAACAGGGGCATCAGGCAGTGTGATTAATTTGTTTACCGCAGCCACTGCTTTTCATTTTGTTGAGT
GTGAATCTGGATTAATGGCGGATGAGTGTCGTGAACAGCTACAAGCTTTTTTTAAGCGTAGACGAAAAGAGAAAAAAGAA
GAGAAACAATTGCAGCGAGAGGTTGAAAAGAAAGACGAATTAGAGAGTAAATAA

Upstream 100 bases:

>100_bases
CCTAAAGAAGGTATTTGGGCGGTATATCCAAACAATCGACACCTTTCAACAAAAGTTCGTTTATTGGTTGAGTTCTTAGC
AAAAGAGTTAGCAGAATAGA

Downstream 100 bases:

>100_bases
CAGAAAGCAGAGACAAAAAGGCAAGTTCACGGTTAATTTGCCTTTTTAAAGTGCGTTAACAAAGGACGAATAAAGGTAAT
TAACGACAAAAGAGCGCTTC

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MTDLDENKSATFYMQRAIELASIAEGEGEVPVGAVIVLNGEIIGEGWNRSIGTHDATAHAEMMAIKQAGQTVENYRLVNA
TLYVTLEPCPMCAGAIVQSRIKQVFFGAADLKTGASGSVINLFTAATAFHFVECESGLMADECREQLQAFFKRRRKEKKE
EKQLQREVEKKDELESK

Sequences:

>Translated_177_residues
MTDLDENKSATFYMQRAIELASIAEGEGEVPVGAVIVLNGEIIGEGWNRSIGTHDATAHAEMMAIKQAGQTVENYRLVNA
TLYVTLEPCPMCAGAIVQSRIKQVFFGAADLKTGASGSVINLFTAATAFHFVECESGLMADECREQLQAFFKRRRKEKKE
EKQLQREVEKKDELESK
>Mature_176_residues
TDLDENKSATFYMQRAIELASIAEGEGEVPVGAVIVLNGEIIGEGWNRSIGTHDATAHAEMMAIKQAGQTVENYRLVNAT
LYVTLEPCPMCAGAIVQSRIKQVFFGAADLKTGASGSVINLFTAATAFHFVECESGLMADECREQLQAFFKRRRKEKKEE
KQLQREVEKKDELESK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=168, Percent_Identity=35.1190476190476, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=54.7770700636943, Blast_Score=184, Evalue=2e-48,
Organism=Escherichia coli, GI1786616, Length=152, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17541138, Length=164, Percent_Identity=36.5853658536585, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=43.8775510204082, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17555996, Length=79, Percent_Identity=40.5063291139241, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=31.5068493150685, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19579; Mature: 19447

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLDENKSATFYMQRAIELASIAEGEGEVPVGAVIVLNGEIIGEGWNRSIGTHDATAHA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEECCCCCCCCCCCCHHHHH
EMMAIKQAGQTVENYRLVNATLYVTLEPCPMCAGAIVQSRIKQVFFGAADLKTGASGSVI
HHHHHHHHCCHHHHEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCCHH
NLFTAATAFHFVECESGLMADECREQLQAFFKRRRKEKKEEKQLQREVEKKDELESK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDLDENKSATFYMQRAIELASIAEGEGEVPVGAVIVLNGEIIGEGWNRSIGTHDATAHA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEECCCCCCCCCCCCHHHHH
EMMAIKQAGQTVENYRLVNATLYVTLEPCPMCAGAIVQSRIKQVFFGAADLKTGASGSVI
HHHHHHHHCCHHHHEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCCHH
NLFTAATAFHFVECESGLMADECREQLQAFFKRRRKEKKEEKQLQREVEKKDELESK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]