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The map label for this gene is iscR

Identifier: 209694305

GI number: 209694305

Start: 801764

End: 802270

Strand: Direct

Name: iscR

Synonym: VSAL_I0716

Alternate gene names: 209694305

Gene position: 801764-802270 (Clockwise)

Preceding gene: 209694304

Following gene: 209694306

Centisome position: 24.11

GC content: 40.83

Gene sequence:

>507_bases
ATGAAATTAACTTCGAAAGGAAGGTATGCAGTAACGGCAATGCTTGATGTTGCACTGCATGCTCAAGAAGGGCCTGTGCC
ACTTGCCGATATATCGGAACGACAGGGAATTTCATTATCTTATCTTGAACAATTATTCTCTAAATTACGCAAAGCTGGTT
TAGTTGCTAGTGTTCGAGGTCCAGGTGGTGGTTATCGCTTAGGATTAAAACCAGATGAAATTGCGGTTGGAATGGTTATT
TCGGCGGTTGATGAATCGGTTGATGCAACTAAGTGCCATGGTAAAGAAGGTTGTCAAGGTGGCACGCGTTGTTTAACGCA
CACATTGTGGCGTGATTTAAGTTCACGTATCAGTAGCTTCTTAGATGGTATAAGCCTTGGTGAGTTGATGGTTGATAATG
AAGTTCAACAAGTATCAGATCGACAAAACATCGATGCAGCCTTAAATAATGGGTTAGTAACGAATTCAAAATTAACAAAT
TCTGTGGGTGTTAATGTCCGCTTTTGA

Upstream 100 bases:

>100_bases
ATCAGAATACTTGACTAAAATAGTAGGATAAATACTTGACCAAAATGGTCAGGTATGGGAAACTTCATTCCATACGAATA
GTGTGGGTATGAGGTAACTT

Downstream 100 bases:

>100_bases
CGGTCAAACGTCTGTATTCTCGGAGATGAAAATGAAACTGCCAATTTACTTTGATTATTCGGCGACTTGTCCTGTTGATA
AGCGCGTAGCCGATAAAATG

Product: HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MKLTSKGRYAVTAMLDVALHAQEGPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGLKPDEIAVGMVI
SAVDESVDATKCHGKEGCQGGTRCLTHTLWRDLSSRISSFLDGISLGELMVDNEVQQVSDRQNIDAALNNGLVTNSKLTN
SVGVNVRF

Sequences:

>Translated_168_residues
MKLTSKGRYAVTAMLDVALHAQEGPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGLKPDEIAVGMVI
SAVDESVDATKCHGKEGCQGGTRCLTHTLWRDLSSRISSFLDGISLGELMVDNEVQQVSDRQNIDAALNNGLVTNSKLTN
SVGVNVRF
>Mature_168_residues
MKLTSKGRYAVTAMLDVALHAQEGPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGLKPDEIAVGMVI
SAVDESVDATKCHGKEGCQGGTRCLTHTLWRDLSSRISSFLDGISLGELMVDNEVQQVSDRQNIDAALNNGLVTNSKLTN
SVGVNVRF

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788880, Length=147, Percent_Identity=73.469387755102, Blast_Score=195, Evalue=1e-51,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): ISCR_ALISL (B6EGX4)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262233.1
- ProteinModelPortal:   B6EGX4
- GeneID:   6989433
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0716
- HOGENOM:   HBG725923
- OMA:   QHISLSY
- ProtClustDB:   CLSK2396019
- HAMAP:   MF_01176
- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR02010
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 17960; Mature: 17960

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTSKGRYAVTAMLDVALHAQEGPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRG
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
PGGGYRLGLKPDEIAVGMVISAVDESVDATKCHGKEGCQGGTRCLTHTLWRDLSSRISSF
CCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDGISLGELMVDNEVQQVSDRQNIDAALNNGLVTNSKLTNSVGVNVRF
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEC
>Mature Secondary Structure
MKLTSKGRYAVTAMLDVALHAQEGPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRG
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
PGGGYRLGLKPDEIAVGMVISAVDESVDATKCHGKEGCQGGTRCLTHTLWRDLSSRISSF
CCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LDGISLGELMVDNEVQQVSDRQNIDAALNNGLVTNSKLTNSVGVNVRF
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA