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The map label for this gene is argA [H]

Identifier: 209694274

GI number: 209694274

Start: 770708

End: 772057

Strand: Reverse

Name: argA [H]

Synonym: VSAL_I0685

Alternate gene names: 209694274

Gene position: 772057-770708 (Counterclockwise)

Preceding gene: 209694278

Following gene: 209694273

Centisome position: 23.22

GC content: 42.07

Gene sequence:

>1350_bases
ATGAATCGTGTGAAGTTTCGTAGTACTGCTTTAGTTAAAGGCTTTCGCCAATCGGCACCTTATGTGAATGCTCACCGTGA
TAAAACCGTGGTGATTATGCTTGGAGGTGAAGCCATTGCTGACCAAAACTTTGCAAATATCGTTAATGATATTGCTCTCC
TAAACTCTCTTGGGTTACGGATTGTTATTGTTTACGGCACTCGACCTCAAATGCGCTCCCAACTCAAAGAAAATGGTCAT
CATGCGCCTTTTCACAAAGGGATCCGAGTCACCGATGAGCAAACCCTTGAACTCGTCAAGCAAATCGCAGGGCAATTACA
ACTTGATATTACTGCTCGACTATCCATGAGTTTAAATAACACGCCAATGGCAGGTGCACAAATTAACGTTATCAGCGGTA
ACTTCATTATCGCCCAACCGCTTGGCGTTGATGATGGGATTGATTATTGCCACAGTGGTCGTGTTCGCCGTATCGATACC
AATGGTATTAGCCGTATGCTTGACCAGCAATCCATCGTCTTACTTGGCCCTGTCGCCAGTTCCGTCACTGGGGAGTGTTT
TAACTTGCTCTCTGAAGACGTAGCGACCCAATTAGCCATTCGATTAAACGCAGATAAATTAATTGGGTTTTGCTCTGAAC
AAGGTGTTGTTGATAACCAAGGTCATATTTTAGCCGAGCTATTTCCCAATGAAGCAGAAACCATACTTGGGAAATTAGAA
ACGGATCTTAACCCGAAAGATGGAAACTCTACGGGCACCATGCGCTTTTTAAGGGGGGCAATTTCAGCTTGTAAAGCGGG
CGTACCAAGAAGCCACCTTATTAGTTACAAAGAAGATGGGGCATTAATTCAAGAGTTATTTTCTTTTGATGGTATTGGTA
CCCAAGTTGTAATGGCCAGCTCTGAACAAATTCGTGACGCTGAAATTGATGACATTGGTGGTATTATGGATTTAATTCAT
CCATTAGAAGAAGAAGGGATTTTAGTTCGTCGATCTCGTGAGCAACTAGAACAAGAAGTCGCTCAATTTACCATTATTGA
AAAAGACGGATTAGTGATTGCTTGCGCCGCTCTTTACCCTTTTCCTGAAGATGGTATGGCTGAAATGGGCTGCGTTGCGG
TTCACCCTGATTACCGAGACGGAGATCGCGGAGTCACATTACTCAATCGCTTACGCTTTAAAGCCAAGCAATTTAAATTA
TTACAACTGTTTGTTCTTACCACTCGTAGCCTTCATTGGTTTAGAGAGCAAGGGTTTGTTGAAGTTGATGTCTCGCAATT
ACCAATGACAAAACAAAAATTGTATAACTATCAACGTAAATCAAAGATCTTAGTGTTAAAAATTCAATAA

Upstream 100 bases:

>100_bases
ATCTGTAGAAATATTAAGAAAAACTTATGTGACCTTGCACTAAACACTTGCACATAGTTAAATACTTAGTCACTATAAAT
GCATAAATAATTATTCATGG

Downstream 100 bases:

>100_bases
TAAATACCGCAGCGAAATAACTTAGCTGCGGCCTTTACTGTAAAAATTAGCGATTTAAGATTTAATAACCTACCGGATTT
AAAAAATTAACATAGAGTAT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MNRVKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADQNFANIVNDIALLNSLGLRIVIVYGTRPQMRSQLKENGH
HAPFHKGIRVTDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFIIAQPLGVDDGIDYCHSGRVRRIDT
NGISRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVVDNQGHILAELFPNEAETILGKLE
TDLNPKDGNSTGTMRFLRGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQIRDAEIDDIGGIMDLIH
PLEEEGILVRRSREQLEQEVAQFTIIEKDGLVIACAALYPFPEDGMAEMGCVAVHPDYRDGDRGVTLLNRLRFKAKQFKL
LQLFVLTTRSLHWFREQGFVEVDVSQLPMTKQKLYNYQRKSKILVLKIQ

Sequences:

>Translated_449_residues
MNRVKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADQNFANIVNDIALLNSLGLRIVIVYGTRPQMRSQLKENGH
HAPFHKGIRVTDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFIIAQPLGVDDGIDYCHSGRVRRIDT
NGISRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVVDNQGHILAELFPNEAETILGKLE
TDLNPKDGNSTGTMRFLRGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQIRDAEIDDIGGIMDLIH
PLEEEGILVRRSREQLEQEVAQFTIIEKDGLVIACAALYPFPEDGMAEMGCVAVHPDYRDGDRGVTLLNRLRFKAKQFKL
LQLFVLTTRSLHWFREQGFVEVDVSQLPMTKQKLYNYQRKSKILVLKIQ
>Mature_449_residues
MNRVKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADQNFANIVNDIALLNSLGLRIVIVYGTRPQMRSQLKENGH
HAPFHKGIRVTDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFIIAQPLGVDDGIDYCHSGRVRRIDT
NGISRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVVDNQGHILAELFPNEAETILGKLE
TDLNPKDGNSTGTMRFLRGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQIRDAEIDDIGGIMDLIH
PLEEEGILVRRSREQLEQEVAQFTIIEKDGLVIACAALYPFPEDGMAEMGCVAVHPDYRDGDRGVTLLNRLRFKAKQFKL
LQLFVLTTRSLHWFREQGFVEVDVSQLPMTKQKLYNYQRKSKILVLKIQ

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=442, Percent_Identity=66.5158371040724, Blast_Score=615, Evalue=1e-177,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49772; Mature: 49772

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADQNFANIVNDIALLNSLGLR
CCCCCHHHHHHHHHHHHCCCCEECCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHCCCEE
IVIVYGTRPQMRSQLKENGHHAPFHKGIRVTDEQTLELVKQIAGQLQLDITARLSMSLNN
EEEEECCCHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHCCEEEEEEEEEEEEECC
TPMAGAQINVISGNFIIAQPLGVDDGIDYCHSGRVRRIDTNGISRMLDQQSIVLLGPVAS
CCCCCCEEEEEECCEEEEECCCCCCCCHHHCCCCEEEECCHHHHHHHCCCCEEEEECCHH
SVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVVDNQGHILAELFPNEAETILGKLE
HHHHHHHHHHHHHHHHHEEEEECHHHHHEECCCCCEECCCCCEEEEECCCHHHHHHHHHH
TDLNPKDGNSTGTMRFLRGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMAS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEC
SEQIRDAEIDDIGGIMDLIHPLEEEGILVRRSREQLEQEVAQFTIIEKDGLVIACAALYP
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEEEECC
FPEDGMAEMGCVAVHPDYRDGDRGVTLLNRLRFKAKQFKLLQLFVLTTRSLHWFREQGFV
CCCCCCHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
EVDVSQLPMTKQKLYNYQRKSKILVLKIQ
EEEHHHCCCHHHHHHHHHHCCEEEEEEEC
>Mature Secondary Structure
MNRVKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADQNFANIVNDIALLNSLGLR
CCCCCHHHHHHHHHHHHCCCCEECCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHCCCEE
IVIVYGTRPQMRSQLKENGHHAPFHKGIRVTDEQTLELVKQIAGQLQLDITARLSMSLNN
EEEEECCCHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHCCEEEEEEEEEEEEECC
TPMAGAQINVISGNFIIAQPLGVDDGIDYCHSGRVRRIDTNGISRMLDQQSIVLLGPVAS
CCCCCCEEEEEECCEEEEECCCCCCCCHHHCCCCEEEECCHHHHHHHCCCCEEEEECCHH
SVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVVDNQGHILAELFPNEAETILGKLE
HHHHHHHHHHHHHHHHHEEEEECHHHHHEECCCCCEECCCCCEEEEECCCHHHHHHHHHH
TDLNPKDGNSTGTMRFLRGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMAS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEC
SEQIRDAEIDDIGGIMDLIHPLEEEGILVRRSREQLEQEVAQFTIIEKDGLVIACAALYP
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEEEECC
FPEDGMAEMGCVAVHPDYRDGDRGVTLLNRLRFKAKQFKLLQLFVLTTRSLHWFREQGFV
CCCCCCHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
EVDVSQLPMTKQKLYNYQRKSKILVLKIQ
EEEHHHCCCHHHHHHHHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA