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The map label for this gene is mreB [H]

Identifier: 209694078

GI number: 209694078

Start: 541014

End: 542057

Strand: Direct

Name: mreB [H]

Synonym: VSAL_I0483

Alternate gene names: 209694078

Gene position: 541014-542057 (Clockwise)

Preceding gene: 209694077

Following gene: 209694079

Centisome position: 16.27

GC content: 45.88

Gene sequence:

>1044_bases
ATGTTTAAGAAACTTCGTGGCATGTTTTCAAACGATCTTTCAATCGATCTAGGTACTGCCAACACACTTATTTATGTAAA
AGGTCAAGGCATCGTTCTTGATGAACCTTCTGTTGTTGCTATTCGTCAAGACCGTAATGGTTCAGCGAAAAGCGTAGCGG
CTGTTGGTCACGAAGCAAAACGAATGCTAGGTCGTACTCCTGGTAATATTTCTGCTATCCGTCCAATGAAAGATGGCGTT
ATCGCTGACTTTTACGTCACCGAAAAAATGTTGCAACACTTCATTAAGCAAGTGCACGACAACAGCTTCTTACGTCCAAG
CCCACGCGTTCTTGTTTGTGTACCTTGTGGTTCTACGCAAGTTGAACGCCGTGCTATCCGTGAATCAGCTCAAGGTGCTG
GTGCCCGTGAAGTCTTCCTAATTGATGAGCCTATGGCTGCTGCTATCGGCGCTGGCTTACCGGTATCTGAAGCGACCGGT
TCTATGGTGGTTGATATAGGTGGTGGTACAACAGAAGTTGCCGTTATCTCACTGAACGGTGTGGTTTACTCATCGTCTGT
TCGTATTGGTGGTGACCGTTTTGATGAAGCGATCATTAACTACGTACGTCGTAACTACGGTAGCCTTATTGGTGAAGCGA
CGGCTGAGCGCATTAAGCACGAGATCGGTTCTGCATACCCTGGTGATGATGTCCTTGAAATTGAAGTACGTGGTCGTAAC
CTTGCAGAAGGTGTTCCTCGTAGCTTTACACTAAATTCAAACGAAATCTTAGAAGCGCTTCAAGAGCCTCTTTCTGGTAT
CGTTTCAGCAGTAATGGTTGCACTAGAACAGTGTCCACCAGAACTAGCATCTGATGTTTCAGAACACGGCATGGTATTAA
CGGGTGGTGGTGCACTACTTCGTGATTTAGACCGTCTTTTGACTGAAGAAACTGGGATCCCAGTGGTTGTTGCAGAGAAT
CCATTAACATGTGTTGCTCTTGGCGGCGGTAAAGCATTAGAAATGATCGATATGCACGGTGGCGATCTCTTTAGTGACGA
GTAA

Upstream 100 bases:

>100_bases
TGCTTCAGGATTCTGTAGCAATGCCTTGCTGATTAGGCTAGGCATTGGTACATTTAGATATATTTATCTTATTATCACGC
TTTCAGGAAATACGAAGATT

Downstream 100 bases:

>100_bases
TAATAATAACGGGTGAGTGGATATGACTCCAATCTTTGGTAGAGGTCCCTCTCTACAGCTTCGCCTGTTTATTGCTGTAA
TGGTATCGGCTAGCCTTATG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRNGSAKSVAAVGHEAKRMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIKQVHDNSFLRPSPRVLVCVPCGSTQVERRAIRESAQGAGAREVFLIDEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDDVLEIEVRGRN
LAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDVSEHGMVLTGGGALLRDLDRLLTEETGIPVVVAEN
PLTCVALGGGKALEMIDMHGGDLFSDE

Sequences:

>Translated_347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRNGSAKSVAAVGHEAKRMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIKQVHDNSFLRPSPRVLVCVPCGSTQVERRAIRESAQGAGAREVFLIDEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDDVLEIEVRGRN
LAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDVSEHGMVLTGGGALLRDLDRLLTEETGIPVVVAEN
PLTCVALGGGKALEMIDMHGGDLFSDE
>Mature_347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRNGSAKSVAAVGHEAKRMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIKQVHDNSFLRPSPRVLVCVPCGSTQVERRAIRESAQGAGAREVFLIDEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDDVLEIEVRGRN
LAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDVSEHGMVLTGGGALLRDLDRLLTEETGIPVVVAEN
PLTCVALGGGKALEMIDMHGGDLFSDE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=375, Percent_Identity=25.8666666666667, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=92.7953890489914, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788875, Length=247, Percent_Identity=25.1012145748988, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324120, Length=384, Percent_Identity=22.9166666666667, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319972, Length=384, Percent_Identity=22.3958333333333, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36900; Mature: 36900

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRNGSAKSVAAVGHEAK
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHH
RMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIKQVHDNSFLRPSPRVLVCVPCGSTQ
HHHCCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHH
VERRAIRESAQGAGAREVFLIDEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDDVLEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCH
LAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDVSEHGMVLTGGGALL
HHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCCHHH
RDLDRLLTEETGIPVVVAENPLTCVALGGGKALEMIDMHGGDLFSDE
HHHHHHHHHCCCCEEEEECCCEEEEEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRNGSAKSVAAVGHEAK
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHH
RMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIKQVHDNSFLRPSPRVLVCVPCGSTQ
HHHCCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHH
VERRAIRESAQGAGAREVFLIDEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDDVLEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCH
LAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDVSEHGMVLTGGGALL
HHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCCHHH
RDLDRLLTEETGIPVVVAENPLTCVALGGGKALEMIDMHGGDLFSDE
HHHHHHHHHCCCCEEEEECCCEEEEEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]