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The map label for this gene is ilvY [H]

Identifier: 209693710

GI number: 209693710

Start: 114812

End: 115696

Strand: Reverse

Name: ilvY [H]

Synonym: VSAL_I0086

Alternate gene names: 209693710

Gene position: 115696-114812 (Counterclockwise)

Preceding gene: 209693712

Following gene: 209693709

Centisome position: 3.48

GC content: 33.56

Gene sequence:

>885_bases
ATGAATATAAAACTACTTCAAACTTTCCTTCATTTATGTGAAAGCCATAGCTTTACCAACACGTCAAAAGCTATGCACTT
AAGTTTATCTGCATTAAGCCGGCAAATACAAAAATTAGAAGATGAAATTGGTCACCCATTATTTGTCCGTGATAATAGAA
GCGTTGAACTAACAAGCTCAGCAAAGAAATTAATGCCTATCGCTTTAAATATTTGTAGTGAATGGAGTAGTTACAAATCT
AGCTCCAATACTGTAAATAATAGTTTAAAGGGGGAATTGAAATTATTTTGTTCAGTAACCGCAAGCTATAGTCACTTACC
TCAACTCCTAAATAATTTCAAAGTGAATTATCCTCACATTGAAATAAAGCTTTCAACAGGAGATCCAGCTCAAGCAATTA
AGAAAGTAGAAAGTTCAGAGGTTGATATTGCAATATCAGCCATACCAGAAAAAAGATCGAATAAATTAGCTTTTGAAATA
ATAAGTGAAATACCATTATCGATTATTGCTCCCATTGGGAACAACACATTTAGCGGTGATATAAATAAAGAAAATACAAA
TTGGGATACGCTTCCTTTTATTTTACCAAAGGAAGGCACGGCGAGAGAAAGAGCAAATTTATGGTTCAAGGAACAAAAAA
TCAAACCAACAATTTATGCTCAAGTCTCTGGACATGAGGCGATAGTAAGTATGGTTGCTTTAGGGTGTGGTATAGGAATA
GCACCTGACGTTGTAATCAATAACAGCCCAGTAAAAGATAAAATTCAAAGGTTAAATACAACACCTATTGCACCATTTAA
ATTAGGCTTGTGCTGTAAACAATCAAAATTAAATGATTCGGTTATACAAGCTCTTTGGCGGGTAGCTGAAAATACATTTA
TTTAA

Upstream 100 bases:

>100_bases
CATTAGGATAATTCTGTGCATACAAAGATAATAACCAAAGATTAACATTGTAAGAAGTGATATATTAACAATACATGATT
GCAAAATTAACAACTACGAT

Downstream 100 bases:

>100_bases
ATCTATAAACGAAAAAAGGCCTCCCATTGGGAAGCCTTTTAAAATTAGAGCCTAGCGATGTCCTACTCTCACATGGGGAG
ACCCCACACTACCATCGGCG

Product: DNA-binding transcriptional regulator IlvY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNIKLLQTFLHLCESHSFTNTSKAMHLSLSALSRQIQKLEDEIGHPLFVRDNRSVELTSSAKKLMPIALNICSEWSSYKS
SSNTVNNSLKGELKLFCSVTASYSHLPQLLNNFKVNYPHIEIKLSTGDPAQAIKKVESSEVDIAISAIPEKRSNKLAFEI
ISEIPLSIIAPIGNNTFSGDINKENTNWDTLPFILPKEGTARERANLWFKEQKIKPTIYAQVSGHEAIVSMVALGCGIGI
APDVVINNSPVKDKIQRLNTTPIAPFKLGLCCKQSKLNDSVIQALWRVAENTFI

Sequences:

>Translated_294_residues
MNIKLLQTFLHLCESHSFTNTSKAMHLSLSALSRQIQKLEDEIGHPLFVRDNRSVELTSSAKKLMPIALNICSEWSSYKS
SSNTVNNSLKGELKLFCSVTASYSHLPQLLNNFKVNYPHIEIKLSTGDPAQAIKKVESSEVDIAISAIPEKRSNKLAFEI
ISEIPLSIIAPIGNNTFSGDINKENTNWDTLPFILPKEGTARERANLWFKEQKIKPTIYAQVSGHEAIVSMVALGCGIGI
APDVVINNSPVKDKIQRLNTTPIAPFKLGLCCKQSKLNDSVIQALWRVAENTFI
>Mature_294_residues
MNIKLLQTFLHLCESHSFTNTSKAMHLSLSALSRQIQKLEDEIGHPLFVRDNRSVELTSSAKKLMPIALNICSEWSSYKS
SSNTVNNSLKGELKLFCSVTASYSHLPQLLNNFKVNYPHIEIKLSTGDPAQAIKKVESSEVDIAISAIPEKRSNKLAFEI
ISEIPLSIIAPIGNNTFSGDINKENTNWDTLPFILPKEGTARERANLWFKEQKIKPTIYAQVSGHEAIVSMVALGCGIGI
APDVVINNSPVKDKIQRLNTTPIAPFKLGLCCKQSKLNDSVIQALWRVAENTFI

Specific function: This protein activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790208, Length=295, Percent_Identity=43.3898305084746, Blast_Score=270, Evalue=7e-74,
Organism=Escherichia coli, GI1788296, Length=241, Percent_Identity=26.5560165975104, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=23.265306122449, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI145693105, Length=141, Percent_Identity=29.0780141843972, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=25.4980079681275, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI157672245, Length=224, Percent_Identity=22.7678571428571, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790399, Length=263, Percent_Identity=23.574144486692, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=260, Percent_Identity=21.5384615384615, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=297, Percent_Identity=22.5589225589226, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=258, Percent_Identity=20.5426356589147, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48994962, Length=193, Percent_Identity=22.7979274611399, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787601, Length=235, Percent_Identity=20.4255319148936, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=23.2931726907631, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789639, Length=129, Percent_Identity=28.6821705426357, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32588; Mature: 32588

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKLLQTFLHLCESHSFTNTSKAMHLSLSALSRQIQKLEDEIGHPLFVRDNRSVELTSS
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCH
AKKLMPIALNICSEWSSYKSSSNTVNNSLKGELKLFCSVTASYSHLPQLLNNFKVNYPHI
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEE
EIKLSTGDPAQAIKKVESSEVDIAISAIPEKRSNKLAFEIISEIPLSIIAPIGNNTFSGD
EEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCC
INKENTNWDTLPFILPKEGTARERANLWFKEQKIKPTIYAQVSGHEAIVSMVALGCGIGI
CCCCCCCCCCCCEEECCCCCCHHHHHCCEECCCCCCEEEEEECCHHHHHHHHHHHCCCCC
APDVVINNSPVKDKIQRLNTTPIAPFKLGLCCKQSKLNDSVIQALWRVAENTFI
CCCEEECCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIKLLQTFLHLCESHSFTNTSKAMHLSLSALSRQIQKLEDEIGHPLFVRDNRSVELTSS
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCH
AKKLMPIALNICSEWSSYKSSSNTVNNSLKGELKLFCSVTASYSHLPQLLNNFKVNYPHI
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEE
EIKLSTGDPAQAIKKVESSEVDIAISAIPEKRSNKLAFEIISEIPLSIIAPIGNNTFSGD
EEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCC
INKENTNWDTLPFILPKEGTARERANLWFKEQKIKPTIYAQVSGHEAIVSMVALGCGIGI
CCCCCCCCCCCCEEECCCCCCHHHHHCCEECCCCCCEEEEEECCHHHHHHHHHHHCCCCC
APDVVINNSPVKDKIQRLNTTPIAPFKLGLCCKQSKLNDSVIQALWRVAENTFI
CCCEEECCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3003115; 1379743; 9278503; 3550695 [H]