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The map label for this gene is ruvB [H]

Identifier: 197119681

GI number: 197119681

Start: 3812358

End: 3813371

Strand: Direct

Name: ruvB [H]

Synonym: Gbem_3316

Alternate gene names: 197119681

Gene position: 3812358-3813371 (Clockwise)

Preceding gene: 197119680

Following gene: 197119682

Centisome position: 82.61

GC content: 64.69

Gene sequence:

>1014_bases
ATGACCCGCCTTATCAGCGCAGATAAATCAGAAGACGACCTCCTTGAGGCGTCGCTGCGCCCGCGGGCGCTCTCCGACTA
CGTAGGGCAGGAAAAGGCCAAAGGAAACCTGGGACTTTTCATCGACGCCGCCCGCGGCAGAAGCGAGGCGCTCGACCACG
TGCTCCTGTACGGCCCGCCGGGACTCGGCAAGACCACGCTGGCCAACATCATCGCCTGCGAGATGGGGGTCAATATCAAG
TCCACCTCCGGCCCGGTGATCGAGCGTCCCGGCGACCTGGCGGCCATCCTCACCAACCTGGAAGCGCACGACGTCCTTTT
CATCGACGAGATCCACCGCCTCTCGCACGTGGTGGAGGAGATCCTCTACCCGGCCATGGAGGACTTTCAGCTCGACATCA
TCATCGGCCAGGGGCCGAGCGCCCGTACCATCAAGCTCGACCTCCCGAAGTTCACCCTGGTCGGCGCCACCACCCGGGCC
GGGCTCCTTTCCTCACCCTTGAGAGACCGCTTCGGCGTCATCTCCCGCCTGGAGTTCTACACCCACGAAGAACTCGCCTT
CATCATCACCCGTTCCGCCCGCATCTTCGGGATGGCCATAGCGCCCGAAGGGGCCATGGAGCTTGCGCGCCGCAGCCGCG
GGACCCCGAGGATCGCGAACCGCCTACTGCGCCGCGTGCGCGATTTCGCCCAGGTCCGCGCCGACGGCGTTATCACCCGC
GAGGTAGCCGACCAGGCGCTGGCGCTTTTAGAGATAGACGACATGGGGTTCGACATGATGGACCGCGCCATCCTGCTCAC
CATCATCGACAAGTTCGGTGGCGGTCCGGTAGGGCTCGACACCATAGCCGCCGCCATCAGCGAGGAAAGCGACACCATCG
AGGACGTGTACGAGCCGTTCCTGATCCAGAACGGTTTCCTGAACCGCACCCCCAGGGGGCGTGTTGCGACCGCCGCGGCC
TACCGGCATTTCGGCAGAATCGCGCCCGAGCCGCCGCAGGGCAAACTCTTCTAA

Upstream 100 bases:

>100_bases
CGCAGCAGGCGTATCCCTCCGGCATGCCCCTTGACCTTTATCTCCAACTGTTATAATTTGGCCCCTTGCATTTTGCAGGA
TTGCCGCAGCAAGGAGAGCC

Downstream 100 bases:

>100_bases
GCCAATTGACAATTGATAATTGACAATTGACAATGGCAGAGCTTTGTTTGCTTTTCTACTCATTACATCAATACCGGCAC
TGCTTGACCTGACAGCGGGT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTRLISADKSEDDLLEASLRPRALSDYVGQEKAKGNLGLFIDAARGRSEALDHVLLYGPPGLGKTTLANIIACEMGVNIK
STSGPVIERPGDLAAILTNLEAHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPKFTLVGATTRA
GLLSSPLRDRFGVISRLEFYTHEELAFIITRSARIFGMAIAPEGAMELARRSRGTPRIANRLLRRVRDFAQVRADGVITR
EVADQALALLEIDDMGFDMMDRAILLTIIDKFGGGPVGLDTIAAAISEESDTIEDVYEPFLIQNGFLNRTPRGRVATAAA
YRHFGRIAPEPPQGKLF

Sequences:

>Translated_337_residues
MTRLISADKSEDDLLEASLRPRALSDYVGQEKAKGNLGLFIDAARGRSEALDHVLLYGPPGLGKTTLANIIACEMGVNIK
STSGPVIERPGDLAAILTNLEAHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPKFTLVGATTRA
GLLSSPLRDRFGVISRLEFYTHEELAFIITRSARIFGMAIAPEGAMELARRSRGTPRIANRLLRRVRDFAQVRADGVITR
EVADQALALLEIDDMGFDMMDRAILLTIIDKFGGGPVGLDTIAAAISEESDTIEDVYEPFLIQNGFLNRTPRGRVATAAA
YRHFGRIAPEPPQGKLF
>Mature_336_residues
TRLISADKSEDDLLEASLRPRALSDYVGQEKAKGNLGLFIDAARGRSEALDHVLLYGPPGLGKTTLANIIACEMGVNIKS
TSGPVIERPGDLAAILTNLEAHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPKFTLVGATTRAG
LLSSPLRDRFGVISRLEFYTHEELAFIITRSARIFGMAIAPEGAMELARRSRGTPRIANRLLRRVRDFAQVRADGVITRE
VADQALALLEIDDMGFDMMDRAILLTIIDKFGGGPVGLDTIAAAISEESDTIEDVYEPFLIQNGFLNRTPRGRVATAAAY
RHFGRIAPEPPQGKLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=64.9546827794562, Blast_Score=449, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 36933; Mature: 36802

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLISADKSEDDLLEASLRPRALSDYVGQEKAKGNLGLFIDAARGRSEALDHVLLYGPP
CCCCCCCCCCHHHHHHHHCCCHHHHHHHCHHHCCCCCEEEEECCCCHHHHHCEEEEECCC
GLGKTTLANIIACEMGVNIKSTSGPVIERPGDLAAILTNLEAHDVLFIDEIHRLSHVVEE
CCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ILYPAMEDFQLDIIIGQGPSARTIKLDLPKFTLVGATTRAGLLSSPLRDRFGVISRLEFY
HHHHCCCCEEEEEEEECCCCCEEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHHHH
THEELAFIITRSARIFGMAIAPEGAMELARRSRGTPRIANRLLRRVRDFAQVRADGVITR
HHHHEEEEEECCCEEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
EVADQALALLEIDDMGFDMMDRAILLTIIDKFGGGPVGLDTIAAAISEESDTIEDVYEPF
HHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHH
LIQNGFLNRTPRGRVATAAAYRHFGRIAPEPPQGKLF
HHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TRLISADKSEDDLLEASLRPRALSDYVGQEKAKGNLGLFIDAARGRSEALDHVLLYGPP
CCCCCCCCCHHHHHHHHCCCHHHHHHHCHHHCCCCCEEEEECCCCHHHHHCEEEEECCC
GLGKTTLANIIACEMGVNIKSTSGPVIERPGDLAAILTNLEAHDVLFIDEIHRLSHVVEE
CCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ILYPAMEDFQLDIIIGQGPSARTIKLDLPKFTLVGATTRAGLLSSPLRDRFGVISRLEFY
HHHHCCCCEEEEEEEECCCCCEEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHHHH
THEELAFIITRSARIFGMAIAPEGAMELARRSRGTPRIANRLLRRVRDFAQVRADGVITR
HHHHEEEEEECCCEEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
EVADQALALLEIDDMGFDMMDRAILLTIIDKFGGGPVGLDTIAAAISEESDTIEDVYEPF
HHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHH
LIQNGFLNRTPRGRVATAAAYRHFGRIAPEPPQGKLF
HHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA