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The map label for this gene is ato-3 [H]

Identifier: 197117187

GI number: 197117187

Start: 933805

End: 935454

Strand: Direct

Name: ato-3 [H]

Synonym: Gbem_0795

Alternate gene names: 197117187

Gene position: 933805-935454 (Clockwise)

Preceding gene: 197117186

Following gene: 197117188

Centisome position: 20.23

GC content: 63.7

Gene sequence:

>1650_bases
ATGTCGAATTATGGAACCCTGCAGGACCGCGTGCGCTGCAAGTCGCTTCTGAGCAAAGTGATGTCCCCCGAACAGACCAT
CGGCTTTTTCAAGGACGGGATGAACCTGGGCTGGTCCGGTTTTACCCCGGCCGGCTACCCGAAAGCGGTGCCCATCGCCC
TCGCCGACCACGTTGAGAAGAACGGGCTGCAAGGCAAACTGAGGTTCAACCTCTTCATCGGCGCCTCGGTCGGCGCGGAA
ACCGAAGACCGTTGGGCAACCCTCGACATGATCGACCGCCGCTGGCCCTACCAGACCGGCAAGAACATCGCAGCGGGGAT
CAACGCCGGCCGCATTCGCATGGGCGACAAGCACCTCTCCCTGTTCGCCCAGGACCTCGGCTACGGCTTCTACACCAAGG
ACACCCCGAGCGGCAAGCTCGACCTCGCCATCATCGAGGTCTCGGCCATCACCGAAGACGGCGGACTGGTGCTGACCTCT
TCCTGCGGCGTAGTTCCCGAAATCCTGATGATCTGCGACAAGGTCATCCTCGAGGTGAACACCGGACAGCCCTCCTTCGA
GGGGATGCACGACGTGGTGGTCTGCAACCACCCGCCCAAGCGCCAGATCCTGGGGATCACCACCGCCGGCGAGCGCATCG
GCAGCACCTACGTTCCGTGCGACCCCAGCAAGGTGATCGCCGTGGTCGAGTCCAAGCACCGCGACAAGGGGCGCGCCTTC
TCCGAGCAGGACGACACCTCCGAAGCGATCGCCAACAACATCATCGACTTCTTCACCCACGAGGTGAAGGCTGGGCGCCT
GCCGAAGAACCTCCTCCCGCTGCAGTCCGGCGTAGGTTCCATCGCCAACGCGGTCATCGGCGGCCTGGCCAAGGGTCCCT
TCTCGAACCTCACCGTCTTCACCGAGGTGCTGCAGGACACCATGCTCGACCTCTTCGATTCCGGCAAGCTGGACATGGCC
TCTTCCTGCTCACTGTCGCTCTCCGAGACCCCGGGTTTCCCGCGCTTCTTCGACAACATGGAGAAGTACTTCGACAAGAT
CGTGCTGCGCCCGCTCTCCATCTCCAACGCCCCCGAGCCGATCCGCCGCCTTGGGTGCATCGCGATGAACACCCCGGTCG
AGATCGACATCTACGCGCACGCCAACTCGACGCTGGTCGGCGGTACCCGCATGATCAACGGCCTGGGCGGCTCGGGCGAC
TTCCTGAGGAACGGTTTCCTGAAGATCATGCATACGCCGTCCTCCCGCCCCTCCAAGACGGATCCCAACGGTATCTCCTG
CGTGGTGCCGCACTGCTCGCACATCGACCACACCGAGCACGACCTCGACTGCGTCGTCACCGAGCAGGGGCTTGCCGACC
TGCGCGGCATGGCTCCGAAAGAGCGTGCCCGCCGCATCATCGAGAAGTGCGCGCATCCCGACTACAAGCCGATCCTCACC
GAGTACCTCAGCATCGCCGAGAAGCAGTGCCTCGCCAAGGGCGTCGGCCACGAGCCGCAGCTTTGGGACCGCGCCTTCAA
GATGCACCTGAACCTCGCCGCGAACGGTACCATGAAGATCAAGAACTGGGACATGAAGGTCGACCTCTGCGAGGAGGCAG
CCGAGCGCCCGGTGCGCCAGCCGAGCATAGGCGACTCCGCAGCCGTCTAG

Upstream 100 bases:

>100_bases
CATCGACGAGCGGCGCAGCATTTCCACGTTTGAGAAGGGTTGATAGCCCCCTTTTTTTGCGCCATTGGCGTATACGCTAA
AAACAAACAGGAGGAACGTG

Downstream 100 bases:

>100_bases
TAGCTGGCTGAAAAGAAGCACCTAAGACCCCGGTTGCCGAAACGGTACCGGGGTCTTTTCTTTTGCCGGGGATCTTCGGT
GAAATGGCGGTGGCCGGCTC

Product: succinyl:acetate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MSNYGTLQDRVRCKSLLSKVMSPEQTIGFFKDGMNLGWSGFTPAGYPKAVPIALADHVEKNGLQGKLRFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDTPSGKLDLAIIEVSAITEDGGLVLTS
SCGVVPEILMICDKVILEVNTGQPSFEGMHDVVVCNHPPKRQILGITTAGERIGSTYVPCDPSKVIAVVESKHRDKGRAF
SEQDDTSEAIANNIIDFFTHEVKAGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVFTEVLQDTMLDLFDSGKLDMA
SSCSLSLSETPGFPRFFDNMEKYFDKIVLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKIMHTPSSRPSKTDPNGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKERARRIIEKCAHPDYKPILT
EYLSIAEKQCLAKGVGHEPQLWDRAFKMHLNLAANGTMKIKNWDMKVDLCEEAAERPVRQPSIGDSAAV

Sequences:

>Translated_549_residues
MSNYGTLQDRVRCKSLLSKVMSPEQTIGFFKDGMNLGWSGFTPAGYPKAVPIALADHVEKNGLQGKLRFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDTPSGKLDLAIIEVSAITEDGGLVLTS
SCGVVPEILMICDKVILEVNTGQPSFEGMHDVVVCNHPPKRQILGITTAGERIGSTYVPCDPSKVIAVVESKHRDKGRAF
SEQDDTSEAIANNIIDFFTHEVKAGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVFTEVLQDTMLDLFDSGKLDMA
SSCSLSLSETPGFPRFFDNMEKYFDKIVLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKIMHTPSSRPSKTDPNGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKERARRIIEKCAHPDYKPILT
EYLSIAEKQCLAKGVGHEPQLWDRAFKMHLNLAANGTMKIKNWDMKVDLCEEAAERPVRQPSIGDSAAV
>Mature_548_residues
SNYGTLQDRVRCKSLLSKVMSPEQTIGFFKDGMNLGWSGFTPAGYPKAVPIALADHVEKNGLQGKLRFNLFIGASVGAET
EDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDTPSGKLDLAIIEVSAITEDGGLVLTSS
CGVVPEILMICDKVILEVNTGQPSFEGMHDVVVCNHPPKRQILGITTAGERIGSTYVPCDPSKVIAVVESKHRDKGRAFS
EQDDTSEAIANNIIDFFTHEVKAGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVFTEVLQDTMLDLFDSGKLDMAS
SCSLSLSETPGFPRFFDNMEKYFDKIVLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDF
LRNGFLKIMHTPSSRPSKTDPNGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKERARRIIEKCAHPDYKPILTE
YLSIAEKQCLAKGVGHEPQLWDRAFKMHLNLAANGTMKIKNWDMKVDLCEEAAERPVRQPSIGDSAAV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=487, Percent_Identity=42.299794661191, Blast_Score=380, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319456, Length=525, Percent_Identity=57.3333333333333, Blast_Score=600, Evalue=1e-172,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 59917; Mature: 59786

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYGTLQDRVRCKSLLSKVMSPEQTIGFFKDGMNLGWSGFTPAGYPKAVPIALADHVEK
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
NGLQGKLRFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCEEECCCCCEEEECHHHHH
LFAQDLGYGFYTKDTPSGKLDLAIIEVSAITEDGGLVLTSSCGVVPEILMICDKVILEVN
HHHHHHCCCCEECCCCCCCEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHEEEC
TGQPSFEGMHDVVVCNHPPKRQILGITTAGERIGSTYVPCDPSKVIAVVESKHRDKGRAF
CCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCCCCHHHEEEEEHHCCCCCCCCC
SEQDDTSEAIANNIIDFFTHEVKAGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
TEVLQDTMLDLFDSGKLDMASSCSLSLSETPGFPRFFDNMEKYFDKIVLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHCCCEEEEECCCCCCCCC
DPNGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKERARRIIEKCAHPDYKPILT
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHH
EYLSIAEKQCLAKGVGHEPQLWDRAFKMHLNLAANGTMKIKNWDMKVDLCEEAAERPVRQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCEEEEECCCCCHHHHHHHHHCCCCC
PSIGDSAAV
CCCCCCCCC
>Mature Secondary Structure 
SNYGTLQDRVRCKSLLSKVMSPEQTIGFFKDGMNLGWSGFTPAGYPKAVPIALADHVEK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
NGLQGKLRFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINAGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCEEECCCCCEEEECHHHHH
LFAQDLGYGFYTKDTPSGKLDLAIIEVSAITEDGGLVLTSSCGVVPEILMICDKVILEVN
HHHHHHCCCCEECCCCCCCEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHEEEC
TGQPSFEGMHDVVVCNHPPKRQILGITTAGERIGSTYVPCDPSKVIAVVESKHRDKGRAF
CCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCCCCHHHEEEEEHHCCCCCCCCC
SEQDDTSEAIANNIIDFFTHEVKAGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
TEVLQDTMLDLFDSGKLDMASSCSLSLSETPGFPRFFDNMEKYFDKIVLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHCCCEEEEECCCCCCCCC
DPNGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGMAPKERARRIIEKCAHPDYKPILT
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHH
EYLSIAEKQCLAKGVGHEPQLWDRAFKMHLNLAANGTMKIKNWDMKVDLCEEAAERPVRQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCEEEEECCCCCHHHHHHHHHCCCCC
PSIGDSAAV
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]