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The map label for this gene is yhfN [H]

Identifier: 197116965

GI number: 197116965

Start: 688901

End: 690160

Strand: Reverse

Name: yhfN [H]

Synonym: Gbem_0568

Alternate gene names: 197116965

Gene position: 690160-688901 (Counterclockwise)

Preceding gene: 197116966

Following gene: 197116964

Centisome position: 14.95

GC content: 61.59

Gene sequence:

>1260_bases
ATGAAGACCCTCCTGATATCCCTGTTCCTGGTTCGCTTTGCCGTTGCCTACCTGTTGCGTTACCTGAACCTGCGCCACCT
GAAGCGGTACGGCACCACTGTGCCCGAGGGGTTCGCCGGGGCCATAGACCAGGAGGCGCTGGCTAAATCGGCGCGCTACA
CTCTGGAGCAGCACAGGGTAGGTCTCGTTGAGTCAATCTACGACAGCGCGCTGCTTCTCGTTTTCCTGTTCACACCTTTG
CTCCCCCTTTACGACCACTGGATCGCCTCCCTTTCCGGCTCTTACCTGGTCCGGGGGCTCACTTTCATGCTTCTCATCTT
CCTTTCGCAGAGCGTCCTGGAGATCCCCTTCTCGCTCTACAGCACCTTCCGACTGGAGCGGCGCTACGGCTTCAACACCA
CGACGCCCGGCCTCTGGCTTTCCGATTTCTTCAAGTCGATGCTCATTTCGGCACTCCTCGCGGGAATCCTGGTGAGCGCC
GCCCTGTTGCTGGTCCGGCACTCCCCGGAACTCTGGTGGCTCTGGGTCTGGGGCTTCTTCGCGCTCTTCTCCATCACCAT
GATCTACCTCTCGCCCTACGTGATCGAGCCGCTCTTCTCCAAGTTCGAGCCGCTGTCCGATCCTGAGCTGGAAGCGGAGA
TACGGGTCATGCTGGACAGGGCCGGGATCGAGGTGAAGGGGGTGTTGCAGATGGACGCCTCCCGCCGCAGCCTCCACTCC
AACGCCTACTTCACCGGCATAGGCCATGTAAAGCGGATCGTTTTGTACGACACCCTTCTGAAGCAGATGGATCACCAGGA
GTTGCTGACTATCCTGGCGCACGAAACCGGCCACTGGAAGAAGGGGCACATCTGGAAGCAGTTGCTCCTCATGGAGAGCG
TGGCACTCGCGGCCTTCTTCCTGGTGCACCAGTTGATCGGCTGGGGTGGGCTCCCGGGGCTCTTCGGCCACCAAGAGGCC
TCCTTCCCGGCCCAGGTGCTCTTGGTCAGCTTCATCCTCTCCATCGCCTCCTTCCCGTTCACCCCCGTCGGCTCCTGGCT
TTCCCGCCGCAACGAGCGCGAGGCGGACCGGTTTGCCGTAGAGCTCAGCGGGGCTCCGCACGCCCTCGCCTCGGCCCTCG
TCAAGCTCTCCTGCGAGAACCTCTCGAACCTCCATCCTCACCCGCTGTATGCCGGGTTTTATTACAGCCATCCCCCCGTC
GTGGAGAGGGTAGCCGCCCTTAGGGCCATGGCGTCCACCGGCGAGCGTCGGAATAATTAA

Upstream 100 bases:

>100_bases
GCCTTTTTTAGTCAGAAGCCCCGGAGCGGAAAACTTATCCCCGGCCGCTTGCAGAGCTGCCCGGACAGAAACGGACGAAA
ACCCAACTAAAGAGGCCGCC

Downstream 100 bases:

>100_bases
CACGGATCAATTGCGCCGCTAATTTTGCATGGTATTTTTTCTGAGGCCTTGGCCACAAAGATAAGCCACAGGAGCCGATC
CATATGCGTCTGAACATCCT

Product: peptidase M48 family peptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKTLLISLFLVRFAVAYLLRYLNLRHLKRYGTTVPEGFAGAIDQEALAKSARYTLEQHRVGLVESIYDSALLLVFLFTPL
LPLYDHWIASLSGSYLVRGLTFMLLIFLSQSVLEIPFSLYSTFRLERRYGFNTTTPGLWLSDFFKSMLISALLAGILVSA
ALLLVRHSPELWWLWVWGFFALFSITMIYLSPYVIEPLFSKFEPLSDPELEAEIRVMLDRAGIEVKGVLQMDASRRSLHS
NAYFTGIGHVKRIVLYDTLLKQMDHQELLTILAHETGHWKKGHIWKQLLLMESVALAAFFLVHQLIGWGGLPGLFGHQEA
SFPAQVLLVSFILSIASFPFTPVGSWLSRRNEREADRFAVELSGAPHALASALVKLSCENLSNLHPHPLYAGFYYSHPPV
VERVAALRAMASTGERRNN

Sequences:

>Translated_419_residues
MKTLLISLFLVRFAVAYLLRYLNLRHLKRYGTTVPEGFAGAIDQEALAKSARYTLEQHRVGLVESIYDSALLLVFLFTPL
LPLYDHWIASLSGSYLVRGLTFMLLIFLSQSVLEIPFSLYSTFRLERRYGFNTTTPGLWLSDFFKSMLISALLAGILVSA
ALLLVRHSPELWWLWVWGFFALFSITMIYLSPYVIEPLFSKFEPLSDPELEAEIRVMLDRAGIEVKGVLQMDASRRSLHS
NAYFTGIGHVKRIVLYDTLLKQMDHQELLTILAHETGHWKKGHIWKQLLLMESVALAAFFLVHQLIGWGGLPGLFGHQEA
SFPAQVLLVSFILSIASFPFTPVGSWLSRRNEREADRFAVELSGAPHALASALVKLSCENLSNLHPHPLYAGFYYSHPPV
VERVAALRAMASTGERRNN
>Mature_419_residues
MKTLLISLFLVRFAVAYLLRYLNLRHLKRYGTTVPEGFAGAIDQEALAKSARYTLEQHRVGLVESIYDSALLLVFLFTPL
LPLYDHWIASLSGSYLVRGLTFMLLIFLSQSVLEIPFSLYSTFRLERRYGFNTTTPGLWLSDFFKSMLISALLAGILVSA
ALLLVRHSPELWWLWVWGFFALFSITMIYLSPYVIEPLFSKFEPLSDPELEAEIRVMLDRAGIEVKGVLQMDASRRSLHS
NAYFTGIGHVKRIVLYDTLLKQMDHQELLTILAHETGHWKKGHIWKQLLLMESVALAAFFLVHQLIGWGGLPGLFGHQEA
SFPAQVLLVSFILSIASFPFTPVGSWLSRRNEREADRFAVELSGAPHALASALVKLSCENLSNLHPHPLYAGFYYSHPPV
VERVAALRAMASTGERRNN

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=444, Percent_Identity=30.1801801801802, Blast_Score=180, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17505484, Length=445, Percent_Identity=28.9887640449438, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6322577, Length=431, Percent_Identity=32.0185614849188, Blast_Score=189, Evalue=6e-49,
Organism=Drosophila melanogaster, GI19922414, Length=436, Percent_Identity=28.8990825688073, Blast_Score=171, Evalue=7e-43,
Organism=Drosophila melanogaster, GI78707252, Length=412, Percent_Identity=26.9417475728155, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78707254, Length=412, Percent_Identity=26.9417475728155, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24654305, Length=257, Percent_Identity=26.0700389105058, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 47429; Mature: 47429

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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EECCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]