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The map label for this gene is frlC [C]

Identifier: 197116909

GI number: 197116909

Start: 618813

End: 619589

Strand: Direct

Name: frlC [C]

Synonym: Gbem_0511

Alternate gene names: 197116909

Gene position: 618813-619589 (Clockwise)

Preceding gene: 308535169

Following gene: 197116910

Centisome position: 13.41

GC content: 60.23

Gene sequence:

>777_bases
ATGAAAATAGGAGCCATGAACCATCCCTGCCGCAATCCCGCCGACGAGATACGCCGCTTCGCCGACATGGGGCTCGACTT
CATCGACTTGACGTTGGAGCCGCCGCAAGCCGGATGGTGGCAATGCAACTTGCAGCAGATAAAGGCGGCGCTGGCCGAGA
CCGGGATGGGGGTGGTAGGCCACACCGCCTACTATCTCCCCATCGCCCATCCCTTCGAGGAGGTGCGGCGTGGGGCGATC
GACGGATTTCGCCACTGTATTGAGATTTTTGCCGAGCTAGGGGCGAAGGCGATGAACATACATCCCGACGCCCACGCGCC
GATGCATGACCGGTCCTTCGTAATCAGCCAGAACCTGAAGAGCCTGACCGAAATCATGAAGGCGGCGGAGGGGACAGGCG
TGAGTGTCATGGTTGAAAACCTTCCCCGCAACTTCAACTCGGCCGCGCAACTGGCGGAGCTGCTCGATCCCCTTCCGCAA
CTGGGGCTGCACCTCGACATCGGCCACACTGAGTTGATGGTGAAGACGAGCACCGCCGACGAGATCTTGGAGCGTTTCGG
CTCGCGCCTCATGCATGCCCATCTCCACGACAACAAGGGGGGCGATGCCGATCTCCACCTCCCGCTCGGTGCCGGGGTCA
TCGATATTCCCAGGCATCTCGCTGTTTTGAAGAAGTCAGGCTACGACGGCACCATCACCCTCGAAGTATTCACGCCGGAT
ACGAGCTACCTGAAGTACAGCGCCAAGAGGCTTCGTGCCATGTGGGACGAAGCATGA

Upstream 100 bases:

>100_bases
CACCGATGGGGCTTCTTCCTCCGTCGTGCTCTACTGCGGAGACCGACCACGATAGGGTGGCGCTTTTCAACTGCGAGCAT
CTTTTTGGTGGAGGCTTGTC

Downstream 100 bases:

>100_bases
TTTGCTAGGAGAAGCCGTAACCGCTCAAGAAAAGGGCGACCTCGTTGAATACCTGAAGTCGATCTAGCGCCAGCACAACA
CCAATGAAGGTTGAGGAGGG

Product: TIM barrel protein, AP endonuclease family 2/xylose isomerase-like family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKIGAMNHPCRNPADEIRRFADMGLDFIDLTLEPPQAGWWQCNLQQIKAALAETGMGVVGHTAYYLPIAHPFEEVRRGAI
DGFRHCIEIFAELGAKAMNIHPDAHAPMHDRSFVISQNLKSLTEIMKAAEGTGVSVMVENLPRNFNSAAQLAELLDPLPQ
LGLHLDIGHTELMVKTSTADEILERFGSRLMHAHLHDNKGGDADLHLPLGAGVIDIPRHLAVLKKSGYDGTITLEVFTPD
TSYLKYSAKRLRAMWDEA

Sequences:

>Translated_258_residues
MKIGAMNHPCRNPADEIRRFADMGLDFIDLTLEPPQAGWWQCNLQQIKAALAETGMGVVGHTAYYLPIAHPFEEVRRGAI
DGFRHCIEIFAELGAKAMNIHPDAHAPMHDRSFVISQNLKSLTEIMKAAEGTGVSVMVENLPRNFNSAAQLAELLDPLPQ
LGLHLDIGHTELMVKTSTADEILERFGSRLMHAHLHDNKGGDADLHLPLGAGVIDIPRHLAVLKKSGYDGTITLEVFTPD
TSYLKYSAKRLRAMWDEA
>Mature_258_residues
MKIGAMNHPCRNPADEIRRFADMGLDFIDLTLEPPQAGWWQCNLQQIKAALAETGMGVVGHTAYYLPIAHPFEEVRRGAI
DGFRHCIEIFAELGAKAMNIHPDAHAPMHDRSFVISQNLKSLTEIMKAAEGTGVSVMVENLPRNFNSAAQLAELLDPLPQ
LGLHLDIGHTELMVKTSTADEILERFGSRLMHAHLHDNKGGDADLHLPLGAGVIDIPRHLAVLKKSGYDGTITLEVFTPD
TSYLKYSAKRLRAMWDEA

Specific function: Not Clear, May Be Involved In An Isomerization Step. [C]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ1614 and MJ0008 [H]

Homologues:

None

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: NA

Molecular weight: Translated: 28534; Mature: 28534

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGAMNHPCRNPADEIRRFADMGLDFIDLTLEPPQAGWWQCNLQQIKAALAETGMGVVG
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEECCHHHHHHHHHHCCCCHHC
HTAYYLPIAHPFEEVRRGAIDGFRHCIEIFAELGAKAMNIHPDAHAPMHDRSFVISQNLK
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHH
SLTEIMKAAEGTGVSVMVENLPRNFNSAAQLAELLDPLPQLGLHLDIGHTELMVKTSTAD
HHHHHHHHHCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCHH
EILERFGSRLMHAHLHDNKGGDADLHLPLGAGVIDIPRHLAVLKKSGYDGTITLEVFTPD
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCC
TSYLKYSAKRLRAMWDEA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIGAMNHPCRNPADEIRRFADMGLDFIDLTLEPPQAGWWQCNLQQIKAALAETGMGVVG
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEECCHHHHHHHHHHCCCCHHC
HTAYYLPIAHPFEEVRRGAIDGFRHCIEIFAELGAKAMNIHPDAHAPMHDRSFVISQNLK
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHH
SLTEIMKAAEGTGVSVMVENLPRNFNSAAQLAELLDPLPQLGLHLDIGHTELMVKTSTAD
HHHHHHHHHCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCHH
EILERFGSRLMHAHLHDNKGGDADLHLPLGAGVIDIPRHLAVLKKSGYDGTITLEVFTPD
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCC
TSYLKYSAKRLRAMWDEA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]