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The map label for this gene is proW [C]

Identifier: 197116829

GI number: 197116829

Start: 509468

End: 511204

Strand: Reverse

Name: proW [C]

Synonym: Gbem_0431

Alternate gene names: 197116829

Gene position: 511204-509468 (Counterclockwise)

Preceding gene: 197116830

Following gene: 197116828

Centisome position: 11.08

GC content: 62.41

Gene sequence:

>1737_bases
ATGGCCAACCGGTCGACACCGTTCAGTAAAACAACAGGAAGAGCCGCTCCCAACTTTTGGGACCTGGCCGCCTTTCTCAT
GGTCATGGGGCTCGTCACGCTCTTTGCCTGGGGCAGCCGCGAGATGGGGATACCCTATATGCCGGGTGAGCAGATCCCCC
TTTCGCTCGACCCCGTTAACCTCCCCGAGTACGCGCTGCGCACCGTCTTGCGCATGGCGGCGGCACTGGCGTTTTCGCTC
CTTTTCACCTTCAGCTACGGAACGCTCGCGGCGAAGAGCCGCCGCGCCGAGCGGATACTCGTTCCGCTTTTGAACATACT
CCAGTCGGTCCCCATCCTCGGCTTTCTCTCGGTCACCGTCACCGGCTTCATCGCCATGTTCCCTGGAAAACTTCTCGGGG
TGGAGTGCGCCGCCATCTTCGCCATCTTCACCTCCCAGGCCTGGAACATGGCCTTCAGCTTTTACCAGTCGCTAAAGACC
ATCCCCTCCGACCTGAGCGAGGCCTCGGTCCTCTTCGGGCTCTCTCCCTGGCAGCGCTTCTGGAAGCTGGATGCCCCCTT
CGCCATGCCCCCCTTGATCTGGAACATGATGATGTCGGTCTCGGGGGGATGGTTCTTCGTGGTGGCGTCGGAGGCGATCA
CGGTGGGGAAGACTTCGGTAACCCTCCCCGGGATAGGCTCCTACGTGGCGCAGGCCATCCACTACCGCAGCCTCTCCGCC
ATCGGCTGGGCGCTTTTGACCATGCTGCTGGTGATCCTCGTCTACGACCAGCTGCTCTTTCGCCCCATGGTGGCCTGGGC
CGACAAGTTCAAGTTCGAAACGACCGAAAGCGGCGAGGGAAGCGGCTCCTGGGTGCTGACCCTGTTCCAGCGCGCGAGGC
TCCTGCGCGCCGCCGGACGTTTCCTGGTCAACCGGTGGATCCGGCTCACCGACCTGCTCCCCAGGAGAAAGCAGCGCGCG
AGCTTCCGTGACGCAACGCAGGCCACGATCCCCAAGGCGCAGGAAATTGCCTGGAACGCGCTTCTAGCCATTGGCGTCGC
CGGGGGCGCGTGGCTTTTGGTCCAGTTCGTCGGGGGAGAGGTAGACGGCGCCGAAATTTGGAAGGTCTTCTATCTCGGCT
TCCTGACCCTGGTTCGGGTCACGGTGCTTTTGATCATCGCCAGCCTGATCTGGGTACCCATCGGGGTGTATATCGGGCTC
AACCCGAAATGGGCGACGAGAGTCCAGCCCCTGGCGCAGTTTCTGGCCGCGTTCCCCGCGAACCTTTTCTTCCCGGTGGC
GGTCTTCTTCATGGTCCACTACCACCTCTCACCGGAGATCTGGACCGCCCCGCTGATGATCCTGGGGACTCAGTGGTACA
TCCTTTTCAACGTGATCGGCGGCGCCTCGGCCATCCCTACCGACCTGCGCGAGGCGGCCCGCAACTTCGGCGTCTCCGGG
TGGAAGCTTTGGAAAACGCTGCTTCTCCCCGGCATTTTCCCATCGCTTGTCACCGGGCTCGTCACCGCTGCAGGGGGGAC
CTGGAACGCCAGCATCGTCGCCGAGATCGTCACCTGGGGGAATACGACCCTTACCGCAACCGGTCTCGGGTCGTACATCG
CCATCTGGACCGAGAAAGGGGATTACCCCCGCATCGCCCTGGGCATAGCAGTCATGAGTATTTACGTCTTGGTACTGAAC
CGGTTTTTCTGGGAGCGGCTGTTCACCGTCAGCCAGACCCGCTACCGGCTCGGCTAG

Upstream 100 bases:

>100_bases
GTCCGCGCGTGCTCCGGCATGAGGCCAGGACGACCCGCGTCCGGATAGCTGCGCCTTTACGCAAAAGGGGTAGAGTATCC
GGCAGCACGGAGGAAGCAGG

Downstream 100 bases:

>100_bases
AGGAGAAGAAGGATGGAAGCGACAGACAATAAAGTTCCGCTGCTCAAGCTGAGCAACATAAGAAAGTCGTACAAGAAGTC
CGACTCGGGCGAGCACCTGG

Product: ABC transporter membrane protein

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: ABC Transporter Permease; ABC Transporter Membrane Protein; ABC Transporter Nitrate Permease; ABC Transporter; ABC Anion Transporter; ABC-Type Anion Transport System Permease Component; Anion Transporter Permease Protein; Nitrate ABC Transporter Permease; ABC Transporter Inner Membrane Subunit; ABC Transporter Transmembrane Permease Protein; ABC-Type Anion Transport System; ABC-Type Nitrate Transport Permease; ABC Transport System Permease Protein; Transmembrane ABC Transporter Protein; Nitrate Transport System Permease Protein; Nitrate ABC Transporter Permease Protein; Anion ABC Transporter Permease; Taurine ABC Transporter Permease Protein; Sugar ABC Transporter; Sugar ABC Transporter 1 Permease Protein; Sulfonate Transport Permease Protein; Nitrate Transport System Permease

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MANRSTPFSKTTGRAAPNFWDLAAFLMVMGLVTLFAWGSREMGIPYMPGEQIPLSLDPVNLPEYALRTVLRMAAALAFSL
LFTFSYGTLAAKSRRAERILVPLLNILQSVPILGFLSVTVTGFIAMFPGKLLGVECAAIFAIFTSQAWNMAFSFYQSLKT
IPSDLSEASVLFGLSPWQRFWKLDAPFAMPPLIWNMMMSVSGGWFFVVASEAITVGKTSVTLPGIGSYVAQAIHYRSLSA
IGWALLTMLLVILVYDQLLFRPMVAWADKFKFETTESGEGSGSWVLTLFQRARLLRAAGRFLVNRWIRLTDLLPRRKQRA
SFRDATQATIPKAQEIAWNALLAIGVAGGAWLLVQFVGGEVDGAEIWKVFYLGFLTLVRVTVLLIIASLIWVPIGVYIGL
NPKWATRVQPLAQFLAAFPANLFFPVAVFFMVHYHLSPEIWTAPLMILGTQWYILFNVIGGASAIPTDLREAARNFGVSG
WKLWKTLLLPGIFPSLVTGLVTAAGGTWNASIVAEIVTWGNTTLTATGLGSYIAIWTEKGDYPRIALGIAVMSIYVLVLN
RFFWERLFTVSQTRYRLG

Sequences:

>Translated_578_residues
MANRSTPFSKTTGRAAPNFWDLAAFLMVMGLVTLFAWGSREMGIPYMPGEQIPLSLDPVNLPEYALRTVLRMAAALAFSL
LFTFSYGTLAAKSRRAERILVPLLNILQSVPILGFLSVTVTGFIAMFPGKLLGVECAAIFAIFTSQAWNMAFSFYQSLKT
IPSDLSEASVLFGLSPWQRFWKLDAPFAMPPLIWNMMMSVSGGWFFVVASEAITVGKTSVTLPGIGSYVAQAIHYRSLSA
IGWALLTMLLVILVYDQLLFRPMVAWADKFKFETTESGEGSGSWVLTLFQRARLLRAAGRFLVNRWIRLTDLLPRRKQRA
SFRDATQATIPKAQEIAWNALLAIGVAGGAWLLVQFVGGEVDGAEIWKVFYLGFLTLVRVTVLLIIASLIWVPIGVYIGL
NPKWATRVQPLAQFLAAFPANLFFPVAVFFMVHYHLSPEIWTAPLMILGTQWYILFNVIGGASAIPTDLREAARNFGVSG
WKLWKTLLLPGIFPSLVTGLVTAAGGTWNASIVAEIVTWGNTTLTATGLGSYIAIWTEKGDYPRIALGIAVMSIYVLVLN
RFFWERLFTVSQTRYRLG
>Mature_577_residues
ANRSTPFSKTTGRAAPNFWDLAAFLMVMGLVTLFAWGSREMGIPYMPGEQIPLSLDPVNLPEYALRTVLRMAAALAFSLL
FTFSYGTLAAKSRRAERILVPLLNILQSVPILGFLSVTVTGFIAMFPGKLLGVECAAIFAIFTSQAWNMAFSFYQSLKTI
PSDLSEASVLFGLSPWQRFWKLDAPFAMPPLIWNMMMSVSGGWFFVVASEAITVGKTSVTLPGIGSYVAQAIHYRSLSAI
GWALLTMLLVILVYDQLLFRPMVAWADKFKFETTESGEGSGSWVLTLFQRARLLRAAGRFLVNRWIRLTDLLPRRKQRAS
FRDATQATIPKAQEIAWNALLAIGVAGGAWLLVQFVGGEVDGAEIWKVFYLGFLTLVRVTVLLIIASLIWVPIGVYIGLN
PKWATRVQPLAQFLAAFPANLFFPVAVFFMVHYHLSPEIWTAPLMILGTQWYILFNVIGGASAIPTDLREAARNFGVSGW
KLWKTLLLPGIFPSLVTGLVTAAGGTWNASIVAEIVTWGNTTLTATGLGSYIAIWTEKGDYPRIALGIAVMSIYVLVLNR
FFWERLFTVSQTRYRLG

Specific function: Involved In A Multicomponent Binding-Protein-Dependent Transport System For Glycine Betaine/L-Proline. [C]

COG id: COG4986

COG function: function code P; ABC-type anion transport system, duplicated permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 63996; Mature: 63865

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRSTPFSKTTGRAAPNFWDLAAFLMVMGLVTLFAWGSREMGIPYMPGEQIPLSLDPVN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
LPEYALRTVLRMAAALAFSLLFTFSYGTLAAKSRRAERILVPLLNILQSVPILGFLSVTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TGFIAMFPGKLLGVECAAIFAIFTSQAWNMAFSFYQSLKTIPSDLSEASVLFGLSPWQRF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHH
WKLDAPFAMPPLIWNMMMSVSGGWFFVVASEAITVGKTSVTLPGIGSYVAQAIHYRSLSA
HCCCCCCCCHHHHHHHHHHCCCCEEEEEECCEEEECCCEEECCCHHHHHHHHHHHHHHHH
IGWALLTMLLVILVYDQLLFRPMVAWADKFKFETTESGEGSGSWVLTLFQRARLLRAAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FLVNRWIRLTDLLPRRKQRASFRDATQATIPKAQEIAWNALLAIGVAGGAWLLVQFVGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
VDGAEIWKVFYLGFLTLVRVTVLLIIASLIWVPIGVYIGLNPKWATRVQPLAQFLAAFPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCH
NLFFPVAVFFMVHYHLSPEIWTAPLMILGTQWYILFNVIGGASAIPTDLREAARNFGVSG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCH
WKLWKTLLLPGIFPSLVTGLVTAAGGTWNASIVAEIVTWGNTTLTATGLGSYIAIWTEKG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECCC
DYPRIALGIAVMSIYVLVLNRFFWERLFTVSQTRYRLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANRSTPFSKTTGRAAPNFWDLAAFLMVMGLVTLFAWGSREMGIPYMPGEQIPLSLDPVN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
LPEYALRTVLRMAAALAFSLLFTFSYGTLAAKSRRAERILVPLLNILQSVPILGFLSVTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TGFIAMFPGKLLGVECAAIFAIFTSQAWNMAFSFYQSLKTIPSDLSEASVLFGLSPWQRF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHH
WKLDAPFAMPPLIWNMMMSVSGGWFFVVASEAITVGKTSVTLPGIGSYVAQAIHYRSLSA
HCCCCCCCCHHHHHHHHHHCCCCEEEEEECCEEEECCCEEECCCHHHHHHHHHHHHHHHH
IGWALLTMLLVILVYDQLLFRPMVAWADKFKFETTESGEGSGSWVLTLFQRARLLRAAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FLVNRWIRLTDLLPRRKQRASFRDATQATIPKAQEIAWNALLAIGVAGGAWLLVQFVGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
VDGAEIWKVFYLGFLTLVRVTVLLIIASLIWVPIGVYIGLNPKWATRVQPLAQFLAAFPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCH
NLFFPVAVFFMVHYHLSPEIWTAPLMILGTQWYILFNVIGGASAIPTDLREAARNFGVSG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCH
WKLWKTLLLPGIFPSLVTGLVTAAGGTWNASIVAEIVTWGNTTLTATGLGSYIAIWTEKG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECCC
DYPRIALGIAVMSIYVLVLNRFFWERLFTVSQTRYRLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA