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The map label for this gene is rnz [H]

Identifier: 197116810

GI number: 197116810

Start: 488542

End: 489624

Strand: Direct

Name: rnz [H]

Synonym: Gbem_0412

Alternate gene names: 197116810

Gene position: 488542-489624 (Clockwise)

Preceding gene: 197116808

Following gene: 197116811

Centisome position: 10.59

GC content: 59.28

Gene sequence:

>1083_bases
ATGCCCAAACCTTTTCGCTACCTGGAACCCACCTTTTTTGCCGGTCTCTTTGACGACCCGCTGCTTTTGGTTCGCGTGCG
CCCTACCGGACGTGCTCTTCTCTTCGACTGCGGCAAGATGCACCACCTAGCCAAGAGGGTCTACACCTCCATCGACGCCA
TATTCATCAGCCACGCCCACATGGACCATTTCATGGGGATGGACAGCGTTGTCCGCCACAGCCACGCCTCTCCCCGCACT
ATCGACGTCTTCGGTCCTCCGGGTCTTGCGGCTCGCATGGGTCACAAGTTCTCCTGCTACGATTGGAACCTCGCCGACAC
CTTCTGGGGCAACTTCAGGGTAAGCGAGATAGACGACGGCCGGATCAGCAGCACGCTTTTTAGCGGCCCCGATGCCTTCG
CCGCCAGCAGGGAAGGGGAGCGCTCCGGCGTCCTTTACAGCAACAGGCACCTCACCGTGACCAGCGCGCAGTGCGAGCAC
AGGATACCCGTCCTCGCCTACAAGGTGGAAGAAGGCGCTGCCTTCGTGATTGACGACGAACGGATGGCCGAAGCGTGCGT
CAGAAAAGGCGCGTGGCTGAAGGATCTGGAGAAGCTCTTTCGTGATGGGGAAATGAAGGGGAACCCGGTAAGGCATCTCT
GTGTCAGCGGAGAAGAAGTGGAAGAACGACTGGAACCCGATGCCGCGGCACTGTATCAGCGGATCAGGAAGTTCGAGGAA
CCCGCGAGCATCGGCTATGTCACCGACATCGGGTACTCAGAGGAAAACATGGCGAGCCTGGAAGGATTGGTAAAGGGAGT
GACGCTTCTTGTCTGTGAGTGCGCTTTCCTCGCCTCCGAGCAAACCAAGGCGCGGCTTTCAAGGCACATGAGCACCGCCG
ATTTCAACATGATGTTGGACCGGCTGCGCCCCAAGTACGTGTTGCCGATGCACTTCTCCAAGACCTATCAGCGTGGAAGC
GAGCCCCTGTACCGGGAGATAGAGCCGCCGCCGGGAGTAACAGTGTTGAAGATCCCCGACCGCCTGACCCCCCGCCCGAT
CATGGAAAGCGAGGTGCCGAGGCCGGTGGAACTAAAAACCTGA

Upstream 100 bases:

>100_bases
CCATTCTCCTCTCACATAGGTTTCGTTCTTGATAGGAACTGTAACCCGATCAGACAGTGATGCAATTGATGCAGGTCAAT
CTAATGGTAAAATTCTGCGC

Downstream 100 bases:

>100_bases
TTCACGCAAAGCCGCAAAGGCGCAAAGAAAAACTCCTGGTTTGCTTTGCGCCTTTGCGGCTTTGCGTGAGACGCTTTTTG
CTTTTCTTATCTTGTATCCT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MPKPFRYLEPTFFAGLFDDPLLLVRVRPTGRALLFDCGKMHHLAKRVYTSIDAIFISHAHMDHFMGMDSVVRHSHASPRT
IDVFGPPGLAARMGHKFSCYDWNLADTFWGNFRVSEIDDGRISSTLFSGPDAFAASREGERSGVLYSNRHLTVTSAQCEH
RIPVLAYKVEEGAAFVIDDERMAEACVRKGAWLKDLEKLFRDGEMKGNPVRHLCVSGEEVEERLEPDAAALYQRIRKFEE
PASIGYVTDIGYSEENMASLEGLVKGVTLLVCECAFLASEQTKARLSRHMSTADFNMMLDRLRPKYVLPMHFSKTYQRGS
EPLYREIEPPPGVTVLKIPDRLTPRPIMESEVPRPVELKT

Sequences:

>Translated_360_residues
MPKPFRYLEPTFFAGLFDDPLLLVRVRPTGRALLFDCGKMHHLAKRVYTSIDAIFISHAHMDHFMGMDSVVRHSHASPRT
IDVFGPPGLAARMGHKFSCYDWNLADTFWGNFRVSEIDDGRISSTLFSGPDAFAASREGERSGVLYSNRHLTVTSAQCEH
RIPVLAYKVEEGAAFVIDDERMAEACVRKGAWLKDLEKLFRDGEMKGNPVRHLCVSGEEVEERLEPDAAALYQRIRKFEE
PASIGYVTDIGYSEENMASLEGLVKGVTLLVCECAFLASEQTKARLSRHMSTADFNMMLDRLRPKYVLPMHFSKTYQRGS
EPLYREIEPPPGVTVLKIPDRLTPRPIMESEVPRPVELKT
>Mature_359_residues
PKPFRYLEPTFFAGLFDDPLLLVRVRPTGRALLFDCGKMHHLAKRVYTSIDAIFISHAHMDHFMGMDSVVRHSHASPRTI
DVFGPPGLAARMGHKFSCYDWNLADTFWGNFRVSEIDDGRISSTLFSGPDAFAASREGERSGVLYSNRHLTVTSAQCEHR
IPVLAYKVEEGAAFVIDDERMAEACVRKGAWLKDLEKLFRDGEMKGNPVRHLCVSGEEVEERLEPDAAALYQRIRKFEEP
ASIGYVTDIGYSEENMASLEGLVKGVTLLVCECAFLASEQTKARLSRHMSTADFNMMLDRLRPKYVLPMHFSKTYQRGSE
PLYREIEPPPGVTVLKIPDRLTPRPIMESEVPRPVELKT

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 40742; Mature: 40611

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPFRYLEPTFFAGLFDDPLLLVRVRPTGRALLFDCGKMHHLAKRVYTSIDAIFISHAH
CCCCCCCCCHHHHHHCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
MDHFMGMDSVVRHSHASPRTIDVFGPPGLAARMGHKFSCYDWNLADTFWGNFRVSEIDDG
HHHHCCHHHHHHHCCCCCCEEEEECCCCHHHHHCCCEEEEECCCHHHCCCCEEEEECCCC
RISSTLFSGPDAFAASREGERSGVLYSNRHLTVTSAQCEHRIPVLAYKVEEGAAFVIDDE
CHHHHHCCCCCHHHHCCCCCCCCCEEECCEEEEECCCCCCCCCEEEEEECCCCEEEECCH
RMAEACVRKGAWLKDLEKLFRDGEMKGNPVRHLCVSGEEVEERLEPDAAALYQRIRKFEE
HHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHEEECCCHHHHHHHCCCHHHHHHHHHHHCC
PASIGYVTDIGYSEENMASLEGLVKGVTLLVCECAFLASEQTKARLSRHMSTADFNMMLD
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHH
RLRPKYVLPMHFSKTYQRGSEPLYREIEPPPGVTVLKIPDRLTPRPIMESEVPRPVELKT
HCCCCEEEEEHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure 
PKPFRYLEPTFFAGLFDDPLLLVRVRPTGRALLFDCGKMHHLAKRVYTSIDAIFISHAH
CCCCCCCCHHHHHHCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
MDHFMGMDSVVRHSHASPRTIDVFGPPGLAARMGHKFSCYDWNLADTFWGNFRVSEIDDG
HHHHCCHHHHHHHCCCCCCEEEEECCCCHHHHHCCCEEEEECCCHHHCCCCEEEEECCCC
RISSTLFSGPDAFAASREGERSGVLYSNRHLTVTSAQCEHRIPVLAYKVEEGAAFVIDDE
CHHHHHCCCCCHHHHCCCCCCCCCEEECCEEEEECCCCCCCCCEEEEEECCCCEEEECCH
RMAEACVRKGAWLKDLEKLFRDGEMKGNPVRHLCVSGEEVEERLEPDAAALYQRIRKFEE
HHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHEEECCCHHHHHHHCCCHHHHHHHHHHHCC
PASIGYVTDIGYSEENMASLEGLVKGVTLLVCECAFLASEQTKARLSRHMSTADFNMMLD
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHH
RLRPKYVLPMHFSKTYQRGSEPLYREIEPPPGVTVLKIPDRLTPRPIMESEVPRPVELKT
HCCCCEEEEEHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]