Click here to switch to the map view.

The map label for this gene is metX

Identifier: 197116749

GI number: 197116749

Start: 431140

End: 432243

Strand: Reverse

Name: metX

Synonym: Gbem_0349

Alternate gene names: 197116749

Gene position: 432243-431140 (Counterclockwise)

Preceding gene: 197116750

Following gene: 197116745

Centisome position: 9.37

GC content: 64.13

Gene sequence:

>1104_bases
ATGTCCTACGGCATAGTGACAGAACAGATCGCCACCTTCGATACGGAACTGCGGCTGGAAAGCGGGCGTATCCTGGGGCC
GATCGACATAGCCTACGAGACCTACGGCACCTTGAACGAGTCGCGCTCGAACGCCATCCTGGTGACCCATGCCTGGACCG
GCAGCGCGCACTTGGCCGGTCGCTACAGCGAAGACGAGAAGCGCGCGGGCTGGTGGGACGAAATCGTCGGCCCCGGCGCC
CTTTTGGACACCGACCGCTACTTCGTGATCTGCTCCAACGTGATCGGCTCCTGCTTCGGCTCCACCGGCCCCACCTCGAT
CAACCCGAAGACCGGCAAGCGCTACAACCTGGCCTTCCCGGTGATCACGGTGCGCGACATGGTGAAGGCCCAGGCCCTGC
TCATGGACCGGCTCGGAATCGGGAAGCTTTTCTGCGTGCTGGGGGGGAGCATGGGGGGGATGCAGGCCCTGGAGTGGGCG
ACCCAGTTCCCGGAGCGGGTAGGCTCGGCCGTGGTGCTCGCCACGACGCCGCGCCCTTCGGCGCAGGCCATCTCGCTGAA
CGCCGTGGCGCGCTGGGCCATCTTCAACGACCCTAACTGGAAAAAAGGGGAATACCGGAAGAACCCCAAGGACGGCCTGG
CTTTAGCCCGCGGCATCGGGCACATCACCTTCCTCTCGGACGAATCGATGACGGCCAAGTTCGACCGCCGCTTCTCCGCC
CGCGACGGGCAGTTCGACTTCTTCGGGCAGTTCGAGGTGGAACGCTACCTGACCTACAACGGCTACAACTTCGTGGACCG
CTTCGACGCCAACTCCTTCCTCTACCTCGCCAAGGCGCTCGACCTCTACGACGTCGCCTCGGGGTGCGAATCGCTGGAGG
AAGCCTTCGCGCCGGTTACCGCCCCGATCCAGTTCTTCGCCTTCACCTCGGACTGGCTCTACCCGCCGGCGCAGACCGAG
GAGATGGTCGCATCACTCAAGACGCTGGGAAAACAGGTCGAGTACCACCTGATCACCTCGGCCTACGGCCACGACGCCTT
CCTTTTGGAGCACCAGACCTTCACCCCGCTGGTCGAGTCCTTCCTGGACCGGGTCAAGGTCTAG

Upstream 100 bases:

>100_bases
AAGGCGCTTTAGCTCCATCACCACAAAAGCCCCTTCTCTCATACCGAGACGGGGCTTTTTTAATACCTGCTGCATGCGGC
GCATCATTTAAGAGAGAAAC

Downstream 100 bases:

>100_bases
GCAGCACCCGCCTCGCGCACCGGCCACCCCATAATGGCGGCCACGTCTTCGTTGAGCATCATCTCCTCGCCGCTGGGAAG
GGCAAACACCTTGACCTTGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSYGIVTEQIATFDTELRLESGRILGPIDIAYETYGTLNESRSNAILVTHAWTGSAHLAGRYSEDEKRAGWWDEIVGPGA
LLDTDRYFVICSNVIGSCFGSTGPTSINPKTGKRYNLAFPVITVRDMVKAQALLMDRLGIGKLFCVLGGSMGGMQALEWA
TQFPERVGSAVVLATTPRPSAQAISLNAVARWAIFNDPNWKKGEYRKNPKDGLALARGIGHITFLSDESMTAKFDRRFSA
RDGQFDFFGQFEVERYLTYNGYNFVDRFDANSFLYLAKALDLYDVASGCESLEEAFAPVTAPIQFFAFTSDWLYPPAQTE
EMVASLKTLGKQVEYHLITSAYGHDAFLLEHQTFTPLVESFLDRVKV

Sequences:

>Translated_367_residues
MSYGIVTEQIATFDTELRLESGRILGPIDIAYETYGTLNESRSNAILVTHAWTGSAHLAGRYSEDEKRAGWWDEIVGPGA
LLDTDRYFVICSNVIGSCFGSTGPTSINPKTGKRYNLAFPVITVRDMVKAQALLMDRLGIGKLFCVLGGSMGGMQALEWA
TQFPERVGSAVVLATTPRPSAQAISLNAVARWAIFNDPNWKKGEYRKNPKDGLALARGIGHITFLSDESMTAKFDRRFSA
RDGQFDFFGQFEVERYLTYNGYNFVDRFDANSFLYLAKALDLYDVASGCESLEEAFAPVTAPIQFFAFTSDWLYPPAQTE
EMVASLKTLGKQVEYHLITSAYGHDAFLLEHQTFTPLVESFLDRVKV
>Mature_366_residues
SYGIVTEQIATFDTELRLESGRILGPIDIAYETYGTLNESRSNAILVTHAWTGSAHLAGRYSEDEKRAGWWDEIVGPGAL
LDTDRYFVICSNVIGSCFGSTGPTSINPKTGKRYNLAFPVITVRDMVKAQALLMDRLGIGKLFCVLGGSMGGMQALEWAT
QFPERVGSAVVLATTPRPSAQAISLNAVARWAIFNDPNWKKGEYRKNPKDGLALARGIGHITFLSDESMTAKFDRRFSAR
DGQFDFFGQFEVERYLTYNGYNFVDRFDANSFLYLAKALDLYDVASGCESLEEAFAPVTAPIQFFAFTSDWLYPPAQTEE
MVASLKTLGKQVEYHLITSAYGHDAFLLEHQTFTPLVESFLDRVKV

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=225, Percent_Identity=42.6666666666667, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_GEOBB (B5EAS1)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002137176.1
- ProteinModelPortal:   B5EAS1
- SMR:   B5EAS1
- GeneID:   6783175
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_0349
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   CLSK828845
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 40820; Mature: 40688

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: ACT_SITE 150-150 ACT_SITE 344-344

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYGIVTEQIATFDTELRLESGRILGPIDIAYETYGTLNESRSNAILVTHAWTGSAHLAG
CCCCCHHHHHHHCCCEEEECCCCEECCCEEHHHHHCCCCCCCCCEEEEEEECCCCCEECC
RYSEDEKRAGWWDEIVGPGALLDTDRYFVICSNVIGSCFGSTGPTSINPKTGKRYNLAFP
CCCCCHHCCCCHHHHCCCCCEEECCCEEEEEHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
VITVRDMVKAQALLMDRLGIGKLFCVLGGSMGGMQALEWATQFPERVGSAVVLATTPRPS
HHHHHHHHHHHHHHHHHCCHHHEEEHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
AQAISLNAVARWAIFNDPNWKKGEYRKNPKDGLALARGIGHITFLSDESMTAKFDRRFSA
CCEEEEEHEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCC
RDGQFDFFGQFEVERYLTYNGYNFVDRFDANSFLYLAKALDLYDVASGCESLEEAFAPVT
CCCCEEEEEEEEEEEEEEECCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC
APIQFFAFTSDWLYPPAQTEEMVASLKTLGKQVEYHLITSAYGHDAFLLEHQTFTPLVES
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEECCHHHHHHHH
FLDRVKV
HHHHHCC
>Mature Secondary Structure 
SYGIVTEQIATFDTELRLESGRILGPIDIAYETYGTLNESRSNAILVTHAWTGSAHLAG
CCCCHHHHHHHCCCEEEECCCCEECCCEEHHHHHCCCCCCCCCEEEEEEECCCCCEECC
RYSEDEKRAGWWDEIVGPGALLDTDRYFVICSNVIGSCFGSTGPTSINPKTGKRYNLAFP
CCCCCHHCCCCHHHHCCCCCEEECCCEEEEEHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
VITVRDMVKAQALLMDRLGIGKLFCVLGGSMGGMQALEWATQFPERVGSAVVLATTPRPS
HHHHHHHHHHHHHHHHHCCHHHEEEHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
AQAISLNAVARWAIFNDPNWKKGEYRKNPKDGLALARGIGHITFLSDESMTAKFDRRFSA
CCEEEEEHEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCC
RDGQFDFFGQFEVERYLTYNGYNFVDRFDANSFLYLAKALDLYDVASGCESLEEAFAPVT
CCCCEEEEEEEEEEEEEEECCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC
APIQFFAFTSDWLYPPAQTEEMVASLKTLGKQVEYHLITSAYGHDAFLLEHQTFTPLVES
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEECCHHHHHHHH
FLDRVKV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA