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The map label for this gene is 197104373

Identifier: 197104373

GI number: 197104373

Start: 1000224

End: 1001150

Strand: Direct

Name: 197104373

Synonym: PHZ_c0907

Alternate gene names: NA

Gene position: 1000224-1001150 (Clockwise)

Preceding gene: 197104367

Following gene: 197104374

Centisome position: 25.03

GC content: 72.92

Gene sequence:

>927_bases
ATGGATGTCGCGCTCTACACCCACCACGACATGTTCGACCACCGGCCGGGCGAAGGCCACCCGGAGCGGCCCGAGCGCCT
GCGGGCGGTGATCGACGCGCTGAACGACGCCACCGACCTCGACCTTGCGCCGAACGAGGCCCCCGTCGTCGAGGAGGCCG
ACCTGCTGCGCGTGCACGACCGCGCCTACCTGGACTCGATCTTCCGGATCGTTCCGGCCCACGACGTCCACGAGCTCGAC
GCCGACACCTACATGTCCGCCGGCAGCCTGCTGGCCGCCCGCCGCGCCGCGGCCGCGGTGGTGAAGGCGGTGCGCGACGT
CGCGGCCGGCGAGGCCGAGCGGGCGTTCTGCGCCGTCCGGCCGCCCGGCCACCATGCCGAGCCGGCCACGCCCATGGGCT
TCTGCATCTTCTCGAACGTCGCCGTCGCCGCCCGCGCGGCCCAGGCGGCGGGCCTGCCCCGCGTCGCGGTGGTGGACTTC
GACATCCACCACGGCAACGGCACCCAGGCGGCGTTCAAGGGCAAGCCCGGGCTGTTCCTGGCCTCGATCCAGCAGTGGCC
GATGTGGCCTGGCACCGGGCATCCGTCCGAGAACATCCCCGGCAATATCGCCAACGCCATCTCGCCGCCGGGCGCCTCGG
CCGAATCGTGGCGGCGCGCCTTCGAGGGTCTGATGGAGGAACTGGACGCCTTCGCGCCCGACCTCATCCTGGTCTCGGCC
GGATTCGACGCCCACCGGCGCGATCCCATCGGCGGCGCGGGCCAGAGCCTGGAGGAGCAGGACTTCGCCTGGGCCACGCG
GGCCATCGTGTCGGTCGCCAACGCGCGCGCGAAGGGTCGGGTTGTGTCCTCGCTCGAGGGCGGCTACGACCTCGAAGCTC
TGGCTCGCTCGGCGGTCGCGCACGTGAGGGCCCTGGCGGACGGGTAA

Upstream 100 bases:

>100_bases
GCGCGCGCCCAGCGCCGACAGCGTCTCGGCGTCGCCAGGCCCGGCGCGGCGGATCACGGGATCAGTCATCGGCCCCCCGA
AAGTGCGATATGATGGATAT

Downstream 100 bases:

>100_bases
AGGGCGTAGCGCGCGTGGGCGCCATCGGCATAGGCTCGCGGGTCTGATGGACAAGGTCCTGACCACCCCGCCCCAGGCGA
CGCCGGCGGCCGTCCGGCAC

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDVALYTHHDMFDHRPGEGHPERPERLRAVIDALNDATDLDLAPNEAPVVEEADLLRVHDRAYLDSIFRIVPAHDVHELD
ADTYMSAGSLLAARRAAAAVVKAVRDVAAGEAERAFCAVRPPGHHAEPATPMGFCIFSNVAVAARAAQAAGLPRVAVVDF
DIHHGNGTQAAFKGKPGLFLASIQQWPMWPGTGHPSENIPGNIANAISPPGASAESWRRAFEGLMEELDAFAPDLILVSA
GFDAHRRDPIGGAGQSLEEQDFAWATRAIVSVANARAKGRVVSSLEGGYDLEALARSAVAHVRALADG

Sequences:

>Translated_308_residues
MDVALYTHHDMFDHRPGEGHPERPERLRAVIDALNDATDLDLAPNEAPVVEEADLLRVHDRAYLDSIFRIVPAHDVHELD
ADTYMSAGSLLAARRAAAAVVKAVRDVAAGEAERAFCAVRPPGHHAEPATPMGFCIFSNVAVAARAAQAAGLPRVAVVDF
DIHHGNGTQAAFKGKPGLFLASIQQWPMWPGTGHPSENIPGNIANAISPPGASAESWRRAFEGLMEELDAFAPDLILVSA
GFDAHRRDPIGGAGQSLEEQDFAWATRAIVSVANARAKGRVVSSLEGGYDLEALARSAVAHVRALADG
>Mature_308_residues
MDVALYTHHDMFDHRPGEGHPERPERLRAVIDALNDATDLDLAPNEAPVVEEADLLRVHDRAYLDSIFRIVPAHDVHELD
ADTYMSAGSLLAARRAAAAVVKAVRDVAAGEAERAFCAVRPPGHHAEPATPMGFCIFSNVAVAARAAQAAGLPRVAVVDF
DIHHGNGTQAAFKGKPGLFLASIQQWPMWPGTGHPSENIPGNIANAISPPGASAESWRRAFEGLMEELDAFAPDLILVSA
GFDAHRRDPIGGAGQSLEEQDFAWATRAIVSVANARAKGRVVSSLEGGYDLEALARSAVAHVRALADG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI153085395, Length=257, Percent_Identity=38.9105058365759, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI13128864, Length=328, Percent_Identity=32.6219512195122, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI17158039, Length=244, Percent_Identity=37.7049180327869, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI30795204, Length=244, Percent_Identity=37.7049180327869, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI30795202, Length=244, Percent_Identity=37.7049180327869, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI20070354, Length=338, Percent_Identity=35.207100591716, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI62750347, Length=243, Percent_Identity=37.4485596707819, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI62750349, Length=243, Percent_Identity=37.4485596707819, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI148539870, Length=254, Percent_Identity=36.2204724409449, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI169234807, Length=254, Percent_Identity=36.2204724409449, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI226529806, Length=327, Percent_Identity=32.1100917431193, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193209491, Length=245, Percent_Identity=36.734693877551, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17540334, Length=312, Percent_Identity=30.1282051282051, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI193206283, Length=312, Percent_Identity=29.8076923076923, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17540332, Length=312, Percent_Identity=29.8076923076923, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17537347, Length=310, Percent_Identity=34.8387096774194, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25154022, Length=298, Percent_Identity=28.1879194630872, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25154020, Length=298, Percent_Identity=27.8523489932886, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324307, Length=323, Percent_Identity=32.5077399380805, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6325141, Length=290, Percent_Identity=26.8965517241379, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360899, Length=322, Percent_Identity=31.6770186335404, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24642146, Length=322, Percent_Identity=31.6770186335404, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24642142, Length=322, Percent_Identity=31.6770186335404, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24642144, Length=322, Percent_Identity=31.6770186335404, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281360801, Length=229, Percent_Identity=39.3013100436681, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360799, Length=229, Percent_Identity=39.3013100436681, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24641720, Length=229, Percent_Identity=39.3013100436681, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32770; Mature: 32770

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVALYTHHDMFDHRPGEGHPERPERLRAVIDALNDATDLDLAPNEAPVVEEADLLRVHD
CCEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
RAYLDSIFRIVPAHDVHELDADTYMSAGSLLAARRAAAAVVKAVRDVAAGEAERAFCAVR
HHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
PPGHHAEPATPMGFCIFSNVAVAARAAQAAGLPRVAVVDFDIHHGNGTQAAFKGKPGLFL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEECCCCCEEE
ASIQQWPMWPGTGHPSENIPGNIANAISPPGASAESWRRAFEGLMEELDAFAPDLILVSA
EHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
GFDAHRRDPIGGAGQSLEEQDFAWATRAIVSVANARAKGRVVSSLEGGYDLEALARSAVA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHH
HVRALADG
HHHHHCCC
>Mature Secondary Structure
MDVALYTHHDMFDHRPGEGHPERPERLRAVIDALNDATDLDLAPNEAPVVEEADLLRVHD
CCEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
RAYLDSIFRIVPAHDVHELDADTYMSAGSLLAARRAAAAVVKAVRDVAAGEAERAFCAVR
HHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
PPGHHAEPATPMGFCIFSNVAVAARAAQAAGLPRVAVVDFDIHHGNGTQAAFKGKPGLFL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEECCCCCEEE
ASIQQWPMWPGTGHPSENIPGNIANAISPPGASAESWRRAFEGLMEELDAFAPDLILVSA
EHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
GFDAHRRDPIGGAGQSLEEQDFAWATRAIVSVANARAKGRVVSSLEGGYDLEALARSAVA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHH
HVRALADG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]