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The map label for this gene is yacD [H]

Identifier: 197104227

GI number: 197104227

Start: 840488

End: 841444

Strand: Direct

Name: yacD [H]

Synonym: PHZ_c0761

Alternate gene names: 197104227

Gene position: 840488-841444 (Clockwise)

Preceding gene: 197104225

Following gene: 197104228

Centisome position: 21.03

GC content: 73.67

Gene sequence:

>957_bases
ATGGCGCCGGCCAAGCCTCTTCGCACCGCCTGCCTCGTCCTGGCGCTCGCCGGGACGCTCGCCGCCTGCGGCGGGAACGG
CGACGGCGACCGGCCGCCCGAGCGGGGCGACGTGGCGGTGGCGCGGGTGGACGGCCGCACGGTCTGGGCCTCGGACGTCA
AGCGCGAGGCGGTGGCCCAGGGGCTGATCGGCGAGGGCGAGCCGCTGGATCCCGCCTCGGACCTGTTCCGCCGGGTGCTG
GACGAGGTGGTGGACCAGAAGCTGCTGGCCGCCGAGGCGCTGAAGCGGAACCTCGACGAGGATCCCGTGGCCCAGCGGCG
CCTCGCCGCCGCCCGCGACCGCATCCTGGGCGACATGCTGATCGAGGACGTGGTCGCCGACGCCGTCACCGAGAACAACA
TCCGCGGCCTCTACGCCGAGCAGCAGCGGGTGGCCAAGCGGCAGGAGGAGATCCGCGCCCGTCAGATCGTGCTCGCCACC
GAGGCCGACGCCGAGGCGGTGAAGAAGCTGCTGGCGGCCGGCGCCTCGTTCGAGGCCCTGGCGATGGAACGCTCGCGCGA
TCCCGAGACGCGCTTCAACGGCGGCGACCTCGGCTACTTCACGACCGACGTCATGCCCGAGGCCTACGAGCTGGCGCTCA
AGACGGCCAAGCCGGGCGAGATCGTGGGCCCCTTCGAGGTGGAGGGCGGCGTCGCCCTCGTGAAGGTCGAGGACCGCCGC
CTGGAGCAGCCGATCACGCTGGAGGCCGCCCGGCCGCAGATCGTGCGCTTCCTGACCTACGACCGCATCCGCGACCTGCT
GGAGAAGCTGCGCGGCAAGGCCAAGATCGAGAGCCTGGTGAAGCCGCAGGACGGCGCGCCCCGCGCCGAACCGCCGGCCG
ATGCCCCCCAGGCGGCCCCCAAGGCGGCGCCCCAGGCGGCGCCCCAGACCCCTCCCAGCAAGGCGAAGACCTCATGA

Upstream 100 bases:

>100_bases
TGGAACTCGGGGCAACCTTTGCATCCCGGGATGGAAATGGCTAGGGACGGCCCGCGCCGGCAACGTGCGGCGCCGCTCCG
GAAAACCTGGGGGTGACCGC

Downstream 100 bases:

>100_bases
GCCGCAAGCCCGCGAAACCGAAGGCGCCCCCCTCCAAGCTCGCGGCCAAGCCCGCCGCCAAGCCGGTGGAGGTGGTCGGC
CAGACGCTCGAGCGCGCGCT

Product: peptidyl-prolyl cis-trans isomerase family protein

Products: Isomerized Proline [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAPAKPLRTACLVLALAGTLAACGGNGDGDRPPERGDVAVARVDGRTVWASDVKREAVAQGLIGEGEPLDPASDLFRRVL
DEVVDQKLLAAEALKRNLDEDPVAQRRLAAARDRILGDMLIEDVVADAVTENNIRGLYAEQQRVAKRQEEIRARQIVLAT
EADAEAVKKLLAAGASFEALAMERSRDPETRFNGGDLGYFTTDVMPEAYELALKTAKPGEIVGPFEVEGGVALVKVEDRR
LEQPITLEAARPQIVRFLTYDRIRDLLEKLRGKAKIESLVKPQDGAPRAEPPADAPQAAPKAAPQAAPQTPPSKAKTS

Sequences:

>Translated_318_residues
MAPAKPLRTACLVLALAGTLAACGGNGDGDRPPERGDVAVARVDGRTVWASDVKREAVAQGLIGEGEPLDPASDLFRRVL
DEVVDQKLLAAEALKRNLDEDPVAQRRLAAARDRILGDMLIEDVVADAVTENNIRGLYAEQQRVAKRQEEIRARQIVLAT
EADAEAVKKLLAAGASFEALAMERSRDPETRFNGGDLGYFTTDVMPEAYELALKTAKPGEIVGPFEVEGGVALVKVEDRR
LEQPITLEAARPQIVRFLTYDRIRDLLEKLRGKAKIESLVKPQDGAPRAEPPADAPQAAPKAAPQAAPQTPPSKAKTS
>Mature_317_residues
APAKPLRTACLVLALAGTLAACGGNGDGDRPPERGDVAVARVDGRTVWASDVKREAVAQGLIGEGEPLDPASDLFRRVLD
EVVDQKLLAAEALKRNLDEDPVAQRRLAAARDRILGDMLIEDVVADAVTENNIRGLYAEQQRVAKRQEEIRARQIVLATE
ADAEAVKKLLAAGASFEALAMERSRDPETRFNGGDLGYFTTDVMPEAYELALKTAKPGEIVGPFEVEGGVALVKVEDRRL
EQPITLEAARPQIVRFLTYDRIRDLLEKLRGKAKIESLVKPQDGAPRAEPPADAPQAAPKAAPQAAPQTPPSKAKTS

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 34246; Mature: 34115

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPAKPLRTACLVLALAGTLAACGGNGDGDRPPERGDVAVARVDGRTVWASDVKREAVAQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEECHHHHHHHHHHH
GLIGEGEPLDPASDLFRRVLDEVVDQKLLAAEALKRNLDEDPVAQRRLAAARDRILGDML
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IEDVVADAVTENNIRGLYAEQQRVAKRQEEIRARQIVLATEADAEAVKKLLAAGASFEAL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCCHHHH
AMERSRDPETRFNGGDLGYFTTDVMPEAYELALKTAKPGEIVGPFEVEGGVALVKVEDRR
HHHHCCCCCCCCCCCCCCEEEHHCCHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECHHH
LEQPITLEAARPQIVRFLTYDRIRDLLEKLRGKAKIESLVKPQDGAPRAEPPADAPQAAP
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KAAPQAAPQTPPSKAKTS
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APAKPLRTACLVLALAGTLAACGGNGDGDRPPERGDVAVARVDGRTVWASDVKREAVAQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEECHHHHHHHHHHH
GLIGEGEPLDPASDLFRRVLDEVVDQKLLAAEALKRNLDEDPVAQRRLAAARDRILGDML
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IEDVVADAVTENNIRGLYAEQQRVAKRQEEIRARQIVLATEADAEAVKKLLAAGASFEAL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCCHHHH
AMERSRDPETRFNGGDLGYFTTDVMPEAYELALKTAKPGEIVGPFEVEGGVALVKVEDRR
HHHHCCCCCCCCCCCCCCEEEHHCCHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECHHH
LEQPITLEAARPQIVRFLTYDRIRDLLEKLRGKAKIESLVKPQDGAPRAEPPADAPQAAP
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KAAPQAAPQTPPSKAKTS
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proline Imidic Peptide Bonds In Oligopeptides [C]

Specific reaction: Cis-Trans Isomerization Of Proline Imidic Peptide Bonds In Oligopeptides. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]