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The map label for this gene is tauD [H]

Identifier: 197104195

GI number: 197104195

Start: 799745

End: 800605

Strand: Direct

Name: tauD [H]

Synonym: PHZ_c0729

Alternate gene names: 197104195

Gene position: 799745-800605 (Clockwise)

Preceding gene: 197104194

Following gene: 197104197

Centisome position: 20.01

GC content: 70.85

Gene sequence:

>861_bases
ATGACCGCCGCCGTGCGCGAGATCGAGGTCCGGCCGCAGCCGACCGGCTTCGGGGCCGAGGTGCGCGGGCTCGACCTGTC
GAGGCCCCTGCCGCCGGGCGTGCTCGAGCAGGTGAAGGCCGCCTGGGCCCGGCACGCGGTCCTGGCCTTTCCCAACCAGC
CGCTGAGCCTGGACGCGCTCGAGGCCTTCACCCTGCAGATCGGGCCGTTCGGCGAGGATCCCTTCATCAAGCCGATGCCG
GGCCATCCGAACGTGCTGGAGTTGCGCCGCGAGCCGGACGAGAAGGCGACCAACTTCGGGGCCGGCTGGCATTCGGACTG
GAGCTTCCAGGCGCGCCCGCCGGCCGCCACCATCCTGCGCTCGGAGATCGTGCCCCCGGTCGGCGGCGACACGCTCTTCT
GCGACGGGGCGCGGGCCTACGAGGCGCTTTCGCCGACCTTCCAGCGGATGCTGGAGGGCCTGCGCGCGGTCCACTCGGCG
ACCCGCGCCTATGGGACCAAGGGCGTCTTCGCCCGCGAGACCGAGAAGCGGACGATGGAGATCATCGTCTCGCCCGAGGC
GGACGCGAGCCTGACCCATCCGCTGGTCCGCACCCATCCGGTGACCGGCCGCAAGGCGCTCTACGTTTCGCCGGTCTACA
CGACAGGGATCGAGGGGCTGACGGTCGAGGAGAGCCAGGCGATCCTGGGCTTCCTGTTCGCGCACATGACCAAGGAGGCG
TTCGTCTACCGCCACAAATGGCGGCCGGGCATGGTGCTGATGTGGGACAACCGCTGCACCGCCCACTTCGCCGAAGGCGG
CTACGACGGCCACCTGCGGGTGATGCACCGCACCACGGTGGCCGGCGAGGTTCCGGTCTGA

Upstream 100 bases:

>100_bases
TATTTGAGATGGAGGGCGGCAAGATCAAGGTCTGGCGCGACTACTTCGACCTCTCCACCTACATCAAGGCGCTGCAGCCC
CCGACCGCGGGAGCGGCGGC

Downstream 100 bases:

>100_bases
ACGCCGTCCACATCATGGCGAGCGGCCATCCGGAGACGCAGGCCTGGAGGGGTTCGCGCGGACCGCCGCCCTTCCTCCAA
GTGACGGTGCATCTGGATGG

Product: alpha-ketoglutarate-dependent taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTAAVREIEVRPQPTGFGAEVRGLDLSRPLPPGVLEQVKAAWARHAVLAFPNQPLSLDALEAFTLQIGPFGEDPFIKPMP
GHPNVLELRREPDEKATNFGAGWHSDWSFQARPPAATILRSEIVPPVGGDTLFCDGARAYEALSPTFQRMLEGLRAVHSA
TRAYGTKGVFARETEKRTMEIIVSPEADASLTHPLVRTHPVTGRKALYVSPVYTTGIEGLTVEESQAILGFLFAHMTKEA
FVYRHKWRPGMVLMWDNRCTAHFAEGGYDGHLRVMHRTTVAGEVPV

Sequences:

>Translated_286_residues
MTAAVREIEVRPQPTGFGAEVRGLDLSRPLPPGVLEQVKAAWARHAVLAFPNQPLSLDALEAFTLQIGPFGEDPFIKPMP
GHPNVLELRREPDEKATNFGAGWHSDWSFQARPPAATILRSEIVPPVGGDTLFCDGARAYEALSPTFQRMLEGLRAVHSA
TRAYGTKGVFARETEKRTMEIIVSPEADASLTHPLVRTHPVTGRKALYVSPVYTTGIEGLTVEESQAILGFLFAHMTKEA
FVYRHKWRPGMVLMWDNRCTAHFAEGGYDGHLRVMHRTTVAGEVPV
>Mature_285_residues
TAAVREIEVRPQPTGFGAEVRGLDLSRPLPPGVLEQVKAAWARHAVLAFPNQPLSLDALEAFTLQIGPFGEDPFIKPMPG
HPNVLELRREPDEKATNFGAGWHSDWSFQARPPAATILRSEIVPPVGGDTLFCDGARAYEALSPTFQRMLEGLRAVHSAT
RAYGTKGVFARETEKRTMEIIVSPEADASLTHPLVRTHPVTGRKALYVSPVYTTGIEGLTVEESQAILGFLFAHMTKEAF
VYRHKWRPGMVLMWDNRCTAHFAEGGYDGHLRVMHRTTVAGEVPV

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=269, Percent_Identity=37.1747211895911, Blast_Score=181, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6322971, Length=273, Percent_Identity=30.4029304029304, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 31558; Mature: 31427

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVREIEVRPQPTGFGAEVRGLDLSRPLPPGVLEQVKAAWARHAVLAFPNQPLSLDAL
CCCCCEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHE
EAFTLQIGPFGEDPFIKPMPGHPNVLELRREPDEKATNFGAGWHSDWSFQARPPAATILR
EEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHH
SEIVPPVGGDTLFCDGARAYEALSPTFQRMLEGLRAVHSATRAYGTKGVFARETEKRTME
HHCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEE
IIVSPEADASLTHPLVRTHPVTGRKALYVSPVYTTGIEGLTVEESQAILGFLFAHMTKEA
EEECCCCCCCCCCCHHHCCCCCCCEEEEECCHHHCCCCCEEECHHHHHHHHHHHHHHHHH
FVYRHKWRPGMVLMWDNRCTAHFAEGGYDGHLRVMHRTTVAGEVPV
HHEEECCCCCEEEEECCCCEEEECCCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TAAVREIEVRPQPTGFGAEVRGLDLSRPLPPGVLEQVKAAWARHAVLAFPNQPLSLDAL
CCCCEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHE
EAFTLQIGPFGEDPFIKPMPGHPNVLELRREPDEKATNFGAGWHSDWSFQARPPAATILR
EEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHH
SEIVPPVGGDTLFCDGARAYEALSPTFQRMLEGLRAVHSATRAYGTKGVFARETEKRTME
HHCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEE
IIVSPEADASLTHPLVRTHPVTGRKALYVSPVYTTGIEGLTVEESQAILGFLFAHMTKEA
EEECCCCCCCCCCCHHHCCCCCCCEEEEECCHHHCCCCCEEECHHHHHHHHHHHHHHHHH
FVYRHKWRPGMVLMWDNRCTAHFAEGGYDGHLRVMHRTTVAGEVPV
HHEEECCCCCEEEEECCCCEEEECCCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]