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The map label for this gene is exuT [H]

Identifier: 197104135

GI number: 197104135

Start: 723428

End: 724756

Strand: Direct

Name: exuT [H]

Synonym: PHZ_c0669

Alternate gene names: 197104135

Gene position: 723428-724756 (Clockwise)

Preceding gene: 197104134

Following gene: 197104136

Centisome position: 18.1

GC content: 71.78

Gene sequence:

>1329_bases
ATGGCGTCCTCCTCCCCGACGCCGGCCGCGGCCGACTCCTCCGCGAGTCCGGCCGCGGCCCTGCGGCCCGCCAAGGGCGC
CTGGCCCGTCCTGGCGATCCTCTGCTTCGTCTACGTGCTGAACTTCCTGGACCGGCAGCTGCTGTCGATCCTGGCCAAGC
CGATCCAGGACGACCTCGGGGTCACCGACGGCCAGCTCGGGCTGATCAGCGGCCTCTACTTCGCGCTGTTCTACTGCCTG
ATCTCGATCCCGGTGGGCTGGCTGGCCGACCGGACCAACCGAGTGCGGGTGCTGGCCTTCGCCTGCGGCCTGTGGAGCGC
GGCCACCGTGGCCTGCGGCCTGTCGGCGAACTATCCGCAGCTCGTCCTCGCCCGGATGACGGTCGGCGTCGGCGAAGCGG
GCGGGGTGCCGCCGTCCTACGCCATCATCACCGACTACTTCCCGCCCGGGCAGCGGGGCACGGCGCTCGGCCTGTTCAAC
CTCGGACCGCCCATCGGCCAGGCCCTGGGCGTGGCCTTCGGCGCGGCCATCGCGGCGGCCTACAGCTGGCGGATGGCCTT
CATCCTGCTGGGCGCCGTCGGCATCGTCACGGCCATCGCCGTCCTGGCGGGCGTGCGCGAGCCCGAGCGGGGCGCCCTGG
ACCGTGCGGCGGGGCAGGCGCCCAAGCTGCAGGCCGGGCCGGCGAAGTTCTGGCCCACGGTGCGGATGTTCTTCTCGACG
CCCGCCCTGGCCCTCGTCGCCTCGGCCAGCGCGGCGACCCAGATCATCACCTACGGCGCGGGCAACTTCACCGTCCTGTT
CCTGATGCGCGAGAAGGGCATGACTCTCGAGGACGTGTCGCTCTGGTACGCCCTGGTGGTCGCCGTCGGCATGGGCGGCG
GGATCTTCGTCTCGGGCCGGGTGATCGACAAGTACACCCGTCGCACGAAGGCGGCCTACGCCCTGGCGCCGGCGGTGTCG
CTGGCGCTCGCGGTGCCGGCGTACCTGGCCTTCGTCTGGGCGCCGTCGTGGCCGCTGGCCCTGGCGTTCCTGCTGTTCCC
GACGTTCCTGAACTACTTCTACCTGTCATCCGCCGTGGCGCTGGTGCAGGAGGAGGTGGCGCCCGAGCAGCGCGTGCTGT
CCGGCGCCCTGCTGCTGCTGGTGATGAACCTGATCGGGATGGGCGTGGGCCCGACGTTCGTCGGGGCGGTGAGCGACCTC
GTCCGGGCCGCCCATCCGGAGAATTCGCTTCAGATCGCGTTCTATGCGCTGGCGCCGATGTACCTCGTCGCCGTGGGGCT
GTTCGTGGCGCTGGCGCGGGTGCTGAGGCGCGAGGAGACCGGCGCGTGA

Upstream 100 bases:

>100_bases
CAAGATCACCTACGTGCATCCGGAGGCGTTCCTCGCCAGCCGGTACGCCGAGCAGCGTCCGCGCACCTTCGGGGTGCGGG
TCGGCTACGACTTCTAGGCC

Downstream 100 bases:

>100_bases
GGGCCCGGGTCGGCACGCTGCGGGGTCTGGGCCTGGCTCTGGGCCTGGCTCTGGGCCTCGCCCTGGCGCTGGGCGCCGGG
CCGGCCCTGGCGCGGTCGGC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MASSSPTPAAADSSASPAAALRPAKGAWPVLAILCFVYVLNFLDRQLLSILAKPIQDDLGVTDGQLGLISGLYFALFYCL
ISIPVGWLADRTNRVRVLAFACGLWSAATVACGLSANYPQLVLARMTVGVGEAGGVPPSYAIITDYFPPGQRGTALGLFN
LGPPIGQALGVAFGAAIAAAYSWRMAFILLGAVGIVTAIAVLAGVREPERGALDRAAGQAPKLQAGPAKFWPTVRMFFST
PALALVASASAATQIITYGAGNFTVLFLMREKGMTLEDVSLWYALVVAVGMGGGIFVSGRVIDKYTRRTKAAYALAPAVS
LALAVPAYLAFVWAPSWPLALAFLLFPTFLNYFYLSSAVALVQEEVAPEQRVLSGALLLLVMNLIGMGVGPTFVGAVSDL
VRAAHPENSLQIAFYALAPMYLVAVGLFVALARVLRREETGA

Sequences:

>Translated_442_residues
MASSSPTPAAADSSASPAAALRPAKGAWPVLAILCFVYVLNFLDRQLLSILAKPIQDDLGVTDGQLGLISGLYFALFYCL
ISIPVGWLADRTNRVRVLAFACGLWSAATVACGLSANYPQLVLARMTVGVGEAGGVPPSYAIITDYFPPGQRGTALGLFN
LGPPIGQALGVAFGAAIAAAYSWRMAFILLGAVGIVTAIAVLAGVREPERGALDRAAGQAPKLQAGPAKFWPTVRMFFST
PALALVASASAATQIITYGAGNFTVLFLMREKGMTLEDVSLWYALVVAVGMGGGIFVSGRVIDKYTRRTKAAYALAPAVS
LALAVPAYLAFVWAPSWPLALAFLLFPTFLNYFYLSSAVALVQEEVAPEQRVLSGALLLLVMNLIGMGVGPTFVGAVSDL
VRAAHPENSLQIAFYALAPMYLVAVGLFVALARVLRREETGA
>Mature_441_residues
ASSSPTPAAADSSASPAAALRPAKGAWPVLAILCFVYVLNFLDRQLLSILAKPIQDDLGVTDGQLGLISGLYFALFYCLI
SIPVGWLADRTNRVRVLAFACGLWSAATVACGLSANYPQLVLARMTVGVGEAGGVPPSYAIITDYFPPGQRGTALGLFNL
GPPIGQALGVAFGAAIAAAYSWRMAFILLGAVGIVTAIAVLAGVREPERGALDRAAGQAPKLQAGPAKFWPTVRMFFSTP
ALALVASASAATQIITYGAGNFTVLFLMREKGMTLEDVSLWYALVVAVGMGGGIFVSGRVIDKYTRRTKAAYALAPAVSL
ALAVPAYLAFVWAPSWPLALAFLLFPTFLNYFYLSSAVALVQEEVAPEQRVLSGALLLLVMNLIGMGVGPTFVGAVSDLV
RAAHPENSLQIAFYALAPMYLVAVGLFVALARVLRREETGA

Specific function: Aldohexuronate transport system [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=422, Percent_Identity=26.0663507109005, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI14042968, Length=422, Percent_Identity=26.0663507109005, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI194239645, Length=455, Percent_Identity=26.5934065934066, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI185136021, Length=404, Percent_Identity=27.4752475247525, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI215490102, Length=236, Percent_Identity=27.9661016949153, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI215490100, Length=392, Percent_Identity=25.2551020408163, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI215490098, Length=236, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI2367379, Length=228, Percent_Identity=29.3859649122807, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082320, Length=194, Percent_Identity=28.3505154639175, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789152, Length=360, Percent_Identity=23.0555555555556, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789515, Length=317, Percent_Identity=23.6593059936909, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI2367193, Length=217, Percent_Identity=27.1889400921659, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082231, Length=185, Percent_Identity=25.9459459459459, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=458, Percent_Identity=25.1091703056769, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193209775, Length=452, Percent_Identity=25.6637168141593, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539092, Length=429, Percent_Identity=25.6410256410256, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71992409, Length=444, Percent_Identity=23.8738738738739, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654037, Length=414, Percent_Identity=24.6376811594203, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24654041, Length=414, Percent_Identity=24.6376811594203, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17864456, Length=411, Percent_Identity=24.330900243309, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654039, Length=411, Percent_Identity=24.330900243309, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654044, Length=205, Percent_Identity=28.2926829268293, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640209, Length=343, Percent_Identity=25.6559766763848, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46355; Mature: 46224

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSSPTPAAADSSASPAAALRPAKGAWPVLAILCFVYVLNFLDRQLLSILAKPIQDDLG
CCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTDGQLGLISGLYFALFYCLISIPVGWLADRTNRVRVLAFACGLWSAATVACGLSANYPQ
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCHH
LVLARMTVGVGEAGGVPPSYAIITDYFPPGQRGTALGLFNLGPPIGQALGVAFGAAIAAA
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
YSWRMAFILLGAVGIVTAIAVLAGVREPERGALDRAAGQAPKLQAGPAKFWPTVRMFFST
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC
PALALVASASAATQIITYGAGNFTVLFLMREKGMTLEDVSLWYALVVAVGMGGGIFVSGR
CHHHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECH
VIDKYTRRTKAAYALAPAVSLALAVPAYLAFVWAPSWPLALAFLLFPTFLNYFYLSSAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVQEEVAPEQRVLSGALLLLVMNLIGMGVGPTFVGAVSDLVRAAHPENSLQIAFYALAPM
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
YLVAVGLFVALARVLRREETGA
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASSSPTPAAADSSASPAAALRPAKGAWPVLAILCFVYVLNFLDRQLLSILAKPIQDDLG
CCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTDGQLGLISGLYFALFYCLISIPVGWLADRTNRVRVLAFACGLWSAATVACGLSANYPQ
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCHH
LVLARMTVGVGEAGGVPPSYAIITDYFPPGQRGTALGLFNLGPPIGQALGVAFGAAIAAA
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
YSWRMAFILLGAVGIVTAIAVLAGVREPERGALDRAAGQAPKLQAGPAKFWPTVRMFFST
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC
PALALVASASAATQIITYGAGNFTVLFLMREKGMTLEDVSLWYALVVAVGMGGGIFVSGR
CHHHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECH
VIDKYTRRTKAAYALAPAVSLALAVPAYLAFVWAPSWPLALAFLLFPTFLNYFYLSSAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVQEEVAPEQRVLSGALLLLVMNLIGMGVGPTFVGAVSDLVRAAHPENSLQIAFYALAPM
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
YLVAVGLFVALARVLRREETGA
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]