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The map label for this gene is yadR [H]

Identifier: 194738261

GI number: 194738261

Start: 239394

End: 239738

Strand: Direct

Name: yadR [H]

Synonym: SeSA_A0227

Alternate gene names: 194738261

Gene position: 239394-239738 (Clockwise)

Preceding gene: 194735314

Following gene: 194737262

Centisome position: 5.08

GC content: 51.01

Gene sequence:

>345_bases
ATGAGTGATGACGTAGCGCTGCCGCTGCAGTTTACCGACGCAGCAGCGAATAAAGTAAAAAGTCTTATCGCTGACGAAGA
TAACCCGAATCTGAAACTGCGCGTGTATATCACCGGCGGTGGTTGCAGCGGCTTCCAGTATGGTTTTACCTTTGACGATC
AGGTTAACGAAGGGGATATGACCATCGAAAAACAGGGCGTTGGCCTGGTGGTTGACCCGATGAGTTTGCAGTATCTGGTG
GGTGGTTCGGTGGATTATACCGAAGGCCTGGAAGGTTCCCGCTTCATTGTAACCAACCCGAATGCGAAAAGTACCTGCGG
GTGTGGCTCTTCCTTCAGCATTTGA

Upstream 100 bases:

>100_bases
TGCGGGCGAGAATACTTGAACGAATTACCAGGGTATTAGATAATGACTGCCAATATTGGGTGAAAATTTATCCAATTACC
GATGTCGTTTGGAGCAAAAT

Downstream 100 bases:

>100_bases
TTGCTGTTCGTTGTGCCGGATGGCGACGCGAGCGTCTTATCCGGCCTACAACATCTTTCCTGTAGGCCCGATAAGCGTAG
CGCCATCGGGCAAAACAATA

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 113

Protein sequence:

>114_residues
MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLV
GGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI

Sequences:

>Translated_114_residues
MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLV
GGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
>Mature_113_residues
SDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVG
GSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=46.9879518072289, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=33.0188679245283, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=99.1228070175439, Blast_Score=231, Evalue=7e-63,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=40, Blast_Score=75, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=40.7407407407407, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=31.7757009345794, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=107, Percent_Identity=31.7757009345794, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=32.0754716981132, Blast_Score=71, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24649697, Length=109, Percent_Identity=40.3669724770642, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=34.5794392523364, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12100; Mature: 11968

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDM
CCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCE
TIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDM
CCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCE
TIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]