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The map label for this gene is mdtQ [H]

Identifier: 194738021

GI number: 194738021

Start: 2289295

End: 2290731

Strand: Reverse

Name: mdtQ [H]

Synonym: SeSA_A2410

Alternate gene names: 194738021

Gene position: 2290731-2289295 (Counterclockwise)

Preceding gene: 194737549

Following gene: 194734285

Centisome position: 48.65

GC content: 58.18

Gene sequence:

>1437_bases
ATGAATCGTAATTCTTTCCTTGCCGCGACAGCGAGCTTACCGCTTTTTATTTTGCTGGCGGGCTGCGCCCCTATGCACGA
TACCCGCCAGTCGCTGACCCAGCAGACGCCCTCTTCTCATGTTGATTCCAGCCTGCCGGCGGCATTGAAAAACGGTTGGC
CGGATAGCCAGTGGTGGAAGGCGTATCACGATGCGCAGCTTGACGCGCTGATTGATAATGCCATACAGCATTCGCCGGAT
ATGCAGGTGGCTGAACAGCGTATTCAACTGGCGGAAGCGCAGGCGAAAGCGGTTGAGGCGCAGGACGGCCCGCAGCTCGA
CTTTTCTGCCGACATTGAGCGCCAGCGAATGTCCGCGGAAGGGCTGATGGGGCCATTCGCGATTACCGACCCCGCGGCGG
GAACGACCGGGCCGTGGTATACCAACGGTACATTCGGCCTGACGGCGGGCTGGGATCTGGATTTATGGGGGAAAAACCGC
GCTGAAGTTACCGCGCGGATCGGGGCGGTCAAAGCGCGCGAAGCGGAGCAGGAGCAGACCCGACAATTGCTGGCAAGCGG
CGTGGCGCGACTCTACTGGGAGTGGCAGACGCAGGCGGCGCTGAAAAATGTGCTGATGCAAATCGAGCATGAGCAGCAAA
ACGTGGTGACGGTAAACCGGGAGCTGTATCAACACGGCATTACTTCTTCTGTTGAAGGGGTCGAGACCGATATCGACGCC
AGCAAAACCCAGCAGCAGCTGAATGACGTTAACGGTAAAATGAAGGTGATTGAAGCGCGGCTCAGCGCGTTAACCAATAC
GCAATCGGCGGCGCTCAAGCTGCGTCAGGTGAGTCTCCCCGCCGTTGAAAGCCAGTTACCGTCGCAACTGGGCTATTCGT
TGCTGGCGCGCCGGGCGGATCTACAGGCCGCGCACTGGTACATTGAATCCTCGTTGAGCAGCATTGACGCCGCGAAGGCT
GCGTTTTATCCCGATATCAATCTGATGGCTTTTTTACAGCAGGATGCGTTACATCTGAGCGATCTGTTCCGCCATTCCGC
ACAGCAATATGGCATTACCGGCGGGCTGACGCTGCCGATTTTCGACAGCGGCAGGCTGAATGCCAACCTCGATATCGCCA
AAGCGCAAAGCAACCTTTCTATCGCCAACTACAACAAAGCGGTGGTAGATGCGGTTAATGATGTGGCGCGCGCTGCCAGT
CAGGTAGAGACGCTGGCGCAGAAAAACCAGCATCAGCAGCAGATTGAGCATGACGCGCAGCGTGTGGTCGGTCTGGCGCA
AGCGCGCTTTAATGCCGGCATTATTGCGGGTTCCCGCGTGAGCGAGGCCAAAATCCCGGCACTGCGCGAGCAGTGTAACG
GCTTGCTGTTGCAGGGCCAGTGGCTGGATGCCTCCATTCAGCTTACCAGCGCGCTGGGCGGCGGTTATCATTCCTGA

Upstream 100 bases:

>100_bases
TATGTCTTTTGTTGTCTGATGATGTATTGCCACGCGTAACTAAAAAATAGATCGTCGTAAGACGTACTCTCTGCGCACCT
TTTTTTATCAGAACACCTCC

Downstream 100 bases:

>100_bases
TTTTTCCGGATGATTCAGACAGGGTTCCTATACTTAGGCTGTGTATGAATCATCCGGAGAGGAATATGACCAAAGTTGCA
ATTGTAACGGCATCAGATTC

Product: multidrug resistance outer membrane protein MdtQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MNRNSFLAATASLPLFILLAGCAPMHDTRQSLTQQTPSSHVDSSLPAALKNGWPDSQWWKAYHDAQLDALIDNAIQHSPD
MQVAEQRIQLAEAQAKAVEAQDGPQLDFSADIERQRMSAEGLMGPFAITDPAAGTTGPWYTNGTFGLTAGWDLDLWGKNR
AEVTARIGAVKAREAEQEQTRQLLASGVARLYWEWQTQAALKNVLMQIEHEQQNVVTVNRELYQHGITSSVEGVETDIDA
SKTQQQLNDVNGKMKVIEARLSALTNTQSAALKLRQVSLPAVESQLPSQLGYSLLARRADLQAAHWYIESSLSSIDAAKA
AFYPDINLMAFLQQDALHLSDLFRHSAQQYGITGGLTLPIFDSGRLNANLDIAKAQSNLSIANYNKAVVDAVNDVARAAS
QVETLAQKNQHQQQIEHDAQRVVGLAQARFNAGIIAGSRVSEAKIPALREQCNGLLLQGQWLDASIQLTSALGGGYHS

Sequences:

>Translated_478_residues
MNRNSFLAATASLPLFILLAGCAPMHDTRQSLTQQTPSSHVDSSLPAALKNGWPDSQWWKAYHDAQLDALIDNAIQHSPD
MQVAEQRIQLAEAQAKAVEAQDGPQLDFSADIERQRMSAEGLMGPFAITDPAAGTTGPWYTNGTFGLTAGWDLDLWGKNR
AEVTARIGAVKAREAEQEQTRQLLASGVARLYWEWQTQAALKNVLMQIEHEQQNVVTVNRELYQHGITSSVEGVETDIDA
SKTQQQLNDVNGKMKVIEARLSALTNTQSAALKLRQVSLPAVESQLPSQLGYSLLARRADLQAAHWYIESSLSSIDAAKA
AFYPDINLMAFLQQDALHLSDLFRHSAQQYGITGGLTLPIFDSGRLNANLDIAKAQSNLSIANYNKAVVDAVNDVARAAS
QVETLAQKNQHQQQIEHDAQRVVGLAQARFNAGIIAGSRVSEAKIPALREQCNGLLLQGQWLDASIQLTSALGGGYHS
>Mature_478_residues
MNRNSFLAATASLPLFILLAGCAPMHDTRQSLTQQTPSSHVDSSLPAALKNGWPDSQWWKAYHDAQLDALIDNAIQHSPD
MQVAEQRIQLAEAQAKAVEAQDGPQLDFSADIERQRMSAEGLMGPFAITDPAAGTTGPWYTNGTFGLTAGWDLDLWGKNR
AEVTARIGAVKAREAEQEQTRQLLASGVARLYWEWQTQAALKNVLMQIEHEQQNVVTVNRELYQHGITSSVEGVETDIDA
SKTQQQLNDVNGKMKVIEARLSALTNTQSAALKLRQVSLPAVESQLPSQLGYSLLARRADLQAAHWYIESSLSSIDAAKA
AFYPDINLMAFLQQDALHLSDLFRHSAQQYGITGGLTLPIFDSGRLNANLDIAKAQSNLSIANYNKAVVDAVNDVARAAS
QVETLAQKNQHQQQIEHDAQRVVGLAQARFNAGIIAGSRVSEAKIPALREQCNGLLLQGQWLDASIQLTSALGGGYHS

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=473, Percent_Identity=36.5750528541226, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1786785, Length=475, Percent_Identity=26.9473684210526, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52109; Mature: 52109

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNSFLAATASLPLFILLAGCAPMHDTRQSLTQQTPSSHVDSSLPAALKNGWPDSQWWK
CCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCCHHHHCCCCCHHHHH
AYHDAQLDALIDNAIQHSPDMQVAEQRIQLAEAQAKAVEAQDGPQLDFSADIERQRMSAE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
GLMGPFAITDPAAGTTGPWYTNGTFGLTAGWDLDLWGKNRAEVTARIGAVKAREAEQEQT
CCCCCCEECCCCCCCCCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
RQLLASGVARLYWEWQTQAALKNVLMQIEHEQQNVVTVNRELYQHGITSSVEGVETDIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCCCCCCCH
SKTQQQLNDVNGKMKVIEARLSALTNTQSAALKLRQVSLPAVESQLPSQLGYSLLARRAD
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHH
LQAAHWYIESSLSSIDAAKAAFYPDINLMAFLQQDALHLSDLFRHSAQQYGITGGLTLPI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FDSGRLNANLDIAKAQSNLSIANYNKAVVDAVNDVARAASQVETLAQKNQHQQQIEHDAQ
ECCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVVGLAQARFNAGIIAGSRVSEAKIPALREQCNGLLLQGQWLDASIQLTSALGGGYHS
HHHHHHHHHHCCCEEECCCCCHHCCHHHHHHCCCEEEECCCCCCCEEEHHHCCCCCCC
>Mature Secondary Structure
MNRNSFLAATASLPLFILLAGCAPMHDTRQSLTQQTPSSHVDSSLPAALKNGWPDSQWWK
CCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCCHHHHCCCCCHHHHH
AYHDAQLDALIDNAIQHSPDMQVAEQRIQLAEAQAKAVEAQDGPQLDFSADIERQRMSAE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
GLMGPFAITDPAAGTTGPWYTNGTFGLTAGWDLDLWGKNRAEVTARIGAVKAREAEQEQT
CCCCCCEECCCCCCCCCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
RQLLASGVARLYWEWQTQAALKNVLMQIEHEQQNVVTVNRELYQHGITSSVEGVETDIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCCCCCCCH
SKTQQQLNDVNGKMKVIEARLSALTNTQSAALKLRQVSLPAVESQLPSQLGYSLLARRAD
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHH
LQAAHWYIESSLSSIDAAKAAFYPDINLMAFLQQDALHLSDLFRHSAQQYGITGGLTLPI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FDSGRLNANLDIAKAQSNLSIANYNKAVVDAVNDVARAASQVETLAQKNQHQQQIEHDAQ
ECCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVVGLAQARFNAGIIAGSRVSEAKIPALREQCNGLLLQGQWLDASIQLTSALGGGYHS
HHHHHHHHHHCCCEEECCCCCHHCCHHHHHHCCCEEEECCCCCCCEEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]