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The map label for this gene is tonB [H]

Identifier: 194737918

GI number: 194737918

Start: 1808648

End: 1809376

Strand: Reverse

Name: tonB [H]

Synonym: SeSA_A1870

Alternate gene names: 194737918

Gene position: 1809376-1808648 (Counterclockwise)

Preceding gene: 194734528

Following gene: 194734543

Centisome position: 38.42

GC content: 57.89

Gene sequence:

>729_bases
ATGACCCTTGATTTACCTCGTCGCTTTCCCTGGCCGACACTCCTTTCCGTAGGCATTCATGGTGCTGTAGTGGCAGGTTT
GCTCTATACCTCGGTACATCAGGTTATTGAATTGCCTGCGCCAGCGCAGCCTATCACGGTGACAATGGTTTCACCCGCTG
ACCTGGAGCCGCCCCAGGCGGTTCAGCCGCCGCCGGAGCCAGTGGTTGAACCCGAACCGGAGCCAGAGCCGATCCCTGAA
CCGCCTAAAGAAGCGCCCGTGGTGATTGAGAAACCCAAACCTAAGCCAAAACCCAAGCCAAAACCGAAACCGGAACCGGT
GAAAAAGGTTGAAGAGCAGCCGAAGCGCGAAGTCAAACCGGCCGAGCCGCGTCCTGCCTCACCGTTTGAAAATAGCGCCC
CGGCGCGGCCAACAAGCAGCACCGCGTCGGCGACCAGCAAGCCGGCGGTGAGCGTGCCCACTGGGCCTCGCGCTCTGAGC
CGTAACCAGCCGCAGTATCCGGCGCGAGCACAGGCGTTACGTATTGAAGGCCGCGTAAAGGTGAAGTTTGACGTGACCTC
TGCTGGGCGAGTGGAAAATGTACAGATTCTATCCGCGCAGCCAGCCAATATGTTTGAGCGTGAAGTTAAGAATGCGATGC
GAAAATGGCGCTATGAAGCAGGCAAGCCGGGTTCCGGGCTGGTGGTCAATATTATTTTCCGTCTGAACGGTACGGCGCAG
ATTGAGTAA

Upstream 100 bases:

>100_bases
ATCTTTTAAATGCCGCTATCGGCAATGCCTTATTGAATATGATTGCTATTTGCATTTAAAATTCAGCTCTGGTTTTTCAA
CTGAAACGATTATGACTTCA

Downstream 100 bases:

>100_bases
CTCTGGCGCCGCCAGTAGGAATATACCATCACCTGCTGGCGGCGTAAGTATGTTACCTGACGGGCATACTTAACCCTGAA
CCGGGAGCGGGCGGGGTTTA

Product: transport protein TonB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPIPE
PPKEAPVVIEKPKPKPKPKPKPKPEPVKKVEEQPKREVKPAEPRPASPFENSAPARPTSSTASATSKPAVSVPTGPRALS
RNQPQYPARAQALRIEGRVKVKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
IE

Sequences:

>Translated_242_residues
MTLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPIPE
PPKEAPVVIEKPKPKPKPKPKPKPEPVKKVEEQPKREVKPAEPRPASPFENSAPARPTSSTASATSKPAVSVPTGPRALS
RNQPQYPARAQALRIEGRVKVKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
IE
>Mature_241_residues
TLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPIPEP
PKEAPVVIEKPKPKPKPKPKPKPEPVKKVEEQPKREVKPAEPRPASPFENSAPARPTSSTASATSKPAVSVPTGPRALSR
NQPQYPARAQALRIEGRVKVKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQI
E

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobac

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family [H]

Homologues:

Organism=Escherichia coli, GI1787505, Length=243, Percent_Identity=84.3621399176955, Blast_Score=307, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003538
- InterPro:   IPR006260 [H]

Pfam domain/function: PF03544 TonB [H]

EC number: NA

Molecular weight: Translated: 26324; Mature: 26192

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPKPEPVKKVEEQPKREVKP
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
AEPRPASPFENSAPARPTSSTASATSKPAVSVPTGPRALSRNQPQYPARAQALRIEGRVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCHHEEEEECCEEE
VKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
EEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCEE
IE
CC
>Mature Secondary Structure 
TLDLPRRFPWPTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQPITVTMVSPADLEPPQA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPKPEPVKKVEEQPKREVKP
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
AEPRPASPFENSAPARPTSSTASATSKPAVSVPTGPRALSRNQPQYPARAQALRIEGRVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCHHEEEEECCEEE
VKFDVTSAGRVENVQILSAQPANMFEREVKNAMRKWRYEAGKPGSGLVVNIIFRLNGTAQ
EEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCEE
IE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2266561; 8316087; 11677609 [H]