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The map label for this gene is pphA [H]

Identifier: 194737826

GI number: 194737826

Start: 1928700

End: 1929584

Strand: Reverse

Name: pphA [H]

Synonym: SeSA_A1996

Alternate gene names: 194737826

Gene position: 1929584-1928700 (Counterclockwise)

Preceding gene: 194735534

Following gene: 194737152

Centisome position: 40.98

GC content: 49.38

Gene sequence:

>885_bases
ATGTTTTTAAGGAGGAAGAATATTGAACGTGAACAGGCGATAGTGAGTAGCTCGCTGCGCCAGGGGATAACACTCCCCTG
GCGCAGCCAGTTATATTTTATTGCGATGATAACAAAGCATTTACTCGCTACTGATGAAATTCGCTATTTACAACAGAGCA
CGTTTACTAAGCAAAAAAAATCTGCACACGCTATCTTTTTATATCTGTCCTGGGTAATGAACGACAGGAAAAACATGATG
CGGCCTGAAGAGATTTATCAGCGAATAGAGGCAAAGAATTGGCGGCATGTCTGGGTGGTCGGCGATATCCACGGCTGTTT
TTCAATGTTAATGAAAAAGTTACGTGAGTGTCGATTTGATCCGCAACAAGACTTGTTAGTTTCTGTGGGCGATCTCATTG
ATAGAGGCCCGGACAGCCTGGGTTGCCTGGCTTTACTGCGTGAGTCCTGGATGATGGCGGTTCGCGGCAATCATGAACAA
ATGGCGCTGGATGCGCGGGCCTCATCGCAGTCGACGCTGTGGTTGATGAATGGTGGCGACTGGTTTACCCGCCTGACGGC
TGAACACGCTGCGCAAGCTGAAGCGCTTTTTATCCTTTGTCAGCGGCTGCCCTGGATACTGGAAGTTCGCTGCCGCCATA
GCACGCATGTGATCGCTCATGCAGATTATCCAGCGTCAACCTATCAATGGCAAAAAAAGGTCGACTTACATCAGGTTCTC
TGGAGCCGCGAACGGCTCATAAATAAGCGTGGCGGGATTAGCGGAGCCGATCATTTTTGGTTTGGCCATACGCCGTTGCG
CCGGCGCATGGATTTTGCCAACGTACACTATATTGATACAGGCGCGGTATTTGGCGGGCAATTGACGTTAGCGCGGATAC
AATAG

Upstream 100 bases:

>100_bases
CGGTAACGACACCTGCATTGGCGCTGGTTTGCCTTGCAACTCACTCAGCTGAAGAGTGTGCTGAAGCCTGTGGTGTCGAT
ATGTGGTTTATGTTTCCGAT

Downstream 100 bases:

>100_bases
CGGTATCAGCGACCAGGGTTAAAAATCGCTATATTGCTGCGCAGGTCGCCAGAAGCCGTCGATAAAATCCTCTACCGGAA
AACAGCCGCCATGGCGAATC

Product: serine/threonine protein phosphatase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MFLRRKNIEREQAIVSSSLRQGITLPWRSQLYFIAMITKHLLATDEIRYLQQSTFTKQKKSAHAIFLYLSWVMNDRKNMM
RPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKKLRECRFDPQQDLLVSVGDLIDRGPDSLGCLALLRESWMMAVRGNHEQ
MALDARASSQSTLWLMNGGDWFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQVL
WSRERLINKRGGISGADHFWFGHTPLRRRMDFANVHYIDTGAVFGGQLTLARIQ

Sequences:

>Translated_294_residues
MFLRRKNIEREQAIVSSSLRQGITLPWRSQLYFIAMITKHLLATDEIRYLQQSTFTKQKKSAHAIFLYLSWVMNDRKNMM
RPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKKLRECRFDPQQDLLVSVGDLIDRGPDSLGCLALLRESWMMAVRGNHEQ
MALDARASSQSTLWLMNGGDWFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQVL
WSRERLINKRGGISGADHFWFGHTPLRRRMDFANVHYIDTGAVFGGQLTLARIQ
>Mature_294_residues
MFLRRKNIEREQAIVSSSLRQGITLPWRSQLYFIAMITKHLLATDEIRYLQQSTFTKQKKSAHAIFLYLSWVMNDRKNMM
RPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKKLRECRFDPQQDLLVSVGDLIDRGPDSLGCLALLRESWMMAVRGNHEQ
MALDARASSQSTLWLMNGGDWFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQVL
WSRERLINKRGGISGADHFWFGHTPLRRRMDFANVHYIDTGAVFGGQLTLARIQ

Specific function: Can hydrolyze phosphorylated Ser-, Thr- or Tyr- substrates in vitro. The natural substrate is unknown [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPP phosphatase family. PP-1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081988, Length=218, Percent_Identity=63.302752293578, Blast_Score=294, Evalue=5e-81,
Organism=Escherichia coli, GI1789090, Length=217, Percent_Identity=42.8571428571429, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 34382; Mature: 34382

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00125 SER_THR_PHOSPHATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLRRKNIEREQAIVSSSLRQGITLPWRSQLYFIAMITKHLLATDEIRYLQQSTFTKQKK
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAHAIFLYLSWVMNDRKNMMRPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKKLRECRFD
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCC
PQQDLLVSVGDLIDRGPDSLGCLALLRESWMMAVRGNHEQMALDARASSQSTLWLMNGGD
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCEEEEEECCC
WFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQVL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHH
WSRERLINKRGGISGADHFWFGHTPLRRRMDFANVHYIDTGAVFGGQLTLARIQ
HHHHHHHHHCCCCCCCCCCEECCCHHHHHCCCCCEEEEECCCEECCEEEEEEEC
>Mature Secondary Structure
MFLRRKNIEREQAIVSSSLRQGITLPWRSQLYFIAMITKHLLATDEIRYLQQSTFTKQKK
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAHAIFLYLSWVMNDRKNMMRPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKKLRECRFD
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCC
PQQDLLVSVGDLIDRGPDSLGCLALLRESWMMAVRGNHEQMALDARASSQSTLWLMNGGD
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCEEEEEECCC
WFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQVL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHH
WSRERLINKRGGISGADHFWFGHTPLRRRMDFANVHYIDTGAVFGGQLTLARIQ
HHHHHHHHHCCCCCCCCCCEECCCHHHHHCCCCCEEEEECCCEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11717262; 11677609 [H]