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The map label for this gene is mdtJ [H]

Identifier: 194737112

GI number: 194737112

Start: 1527712

End: 1528074

Strand: Direct

Name: mdtJ [H]

Synonym: SeSA_A1583

Alternate gene names: 194737112

Gene position: 1527712-1528074 (Clockwise)

Preceding gene: 194736432

Following gene: 194736947

Centisome position: 32.44

GC content: 46.01

Gene sequence:

>363_bases
ATGTTTTACTGGATTTTATTAGCTCTGGCTATCGCGACTGAAATTACCGGCACGCTCTCAATGAAATGGGCTAGCGTGGG
TAATGGCAATGCGGGTTTTATTTTAATGCTGGTGATGATCACGCTGTCATATATATTTCTTTCCTTTGCGGTAAAAAAGA
TTGCCCTGGGTGTGGCGTATGCCTTATGGGAAGGGATCGGCATTTTATTTATTACCATTTTTAGCGTGCTGCTATTTGAT
GAAGCATTATCAACCATGAAGATTGCCGGCTTGCTGACGCTGGTCGCCGGCATCGTATTGATCAAATCAGGGACGCGTAA
ACCCGGCAAACCGGTGAAGGGGGCGGCTCGTGCAACAATTTGA

Upstream 100 bases:

>100_bases
TGCCTGAGCTGGCGCAACGCGCTGTGCTAACTGATTTTATTTTTTAGTTTGCTGCGTGCAGCAGACTCGAAAGAGTATAT
TCTCATGCAGGAGAAGTGTC

Downstream 100 bases:

>100_bases
ATGGATACACGGCGCCTGGCTTGGGCTGGCAATAATGCTGGAAATCGCGGCTAACGTACTGTTGAAATTTTCGGACGGCT
TTCGCCGTAAATGCTATGGC

Product: multidrug efflux system protein MdtJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFD
EALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKGAARATI

Sequences:

>Translated_120_residues
MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFD
EALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKGAARATI
>Mature_120_residues
MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFD
EALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKGAARATI

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=109, Percent_Identity=89.9082568807339, Blast_Score=186, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12813; Mature: 12813

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAY
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKGAARATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAY
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKGAARATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA