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The map label for this gene is hinT [H]

Identifier: 194736719

GI number: 194736719

Start: 1255032

End: 1255409

Strand: Direct

Name: hinT [H]

Synonym: SeSA_A1281

Alternate gene names: 194736719

Gene position: 1255032-1255409 (Clockwise)

Preceding gene: 194735242

Following gene: 194736228

Centisome position: 26.65

GC content: 50.0

Gene sequence:

>378_bases
ATGAAAAAGGAAAACGTCGTGGCAGAAGAAACTATATTCAGCAAAATTATTCGTCGTGAAATCCCTTCGGATATCGTTTA
TCAGGATGAGCTGGTCACCGCCTTTCGTGATATTTCACCGCAGGCGCCGACGCATATCTTGATTATTCCCAATATTCTGA
TCCCAACCGTCAATGACGTGACGGCGGAACATGAACAGGCGTTAGGTCGGATGATCACCGTGGCGGCGAAAATCGCCGAA
CAGGAAGGCATTGCCGAGGATGGGTATCGTTTAATCATGAATACCAACCGTCATGGGGGCCAGGAGGTTTATCATATCCA
TATGCACCTACTGGGCGGCCGCCCGCTAGGCCCGATGCTGGCGCATAAAGGCTTGTAA

Upstream 100 bases:

>100_bases
TTAATAAATCGTGGGTTAAAGTTGAAAGAGCGTCGGTAACTCGCTCATACTCTATACTCGCAGTATGGCTCGGCGTAGCA
TGTGCGCTGCAAGGGCTATT

Downstream 100 bases:

>100_bases
GTATGATCAAAGGATGCATCGCGGTTTCTCTGGGCTTGCTGCTGCTTACCGGCTGCCGGTCACACCCTGAAATTCCGGTA
AGCGACGCGCAGTCGCTGGT

Product: purine nucleoside phosphoramidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKKENVVAEETIFSKIIRREIPSDIVYQDELVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQALGRMITVAAKIAE
QEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPLGPMLAHKGL

Sequences:

>Translated_125_residues
MKKENVVAEETIFSKIIRREIPSDIVYQDELVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQALGRMITVAAKIAE
QEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPLGPMLAHKGL
>Mature_125_residues
MKKENVVAEETIFSKIIRREIPSDIVYQDELVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQALGRMITVAAKIAE
QEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPLGPMLAHKGL

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=109, Percent_Identity=46.7889908256881, Blast_Score=116, Evalue=6e-27,
Organism=Homo sapiens, GI4885413, Length=107, Percent_Identity=46.7289719626168, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1787346, Length=119, Percent_Identity=97.4789915966387, Blast_Score=216, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17506713, Length=113, Percent_Identity=42.4778761061947, Blast_Score=111, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28574010, Length=111, Percent_Identity=43.2432432432432, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24581222, Length=111, Percent_Identity=43.2432432432432, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 13967; Mature: 13967

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKENVVAEETIFSKIIRREIPSDIVYQDELVTAFRDISPQAPTHILIIPNILIPTVNDV
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCEECCCCCCH
TAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPLGPML
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCHHH
AHKGL
HCCCC
>Mature Secondary Structure
MKKENVVAEETIFSKIIRREIPSDIVYQDELVTAFRDISPQAPTHILIIPNILIPTVNDV
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCEECCCCCCH
TAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPLGPML
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCHHH
AHKGL
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]