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The map label for this gene is kdsB [H]

Identifier: 194736600

GI number: 194736600

Start: 1083171

End: 1083917

Strand: Direct

Name: kdsB [H]

Synonym: SeSA_A1102

Alternate gene names: 194736600

Gene position: 1083171-1083917 (Clockwise)

Preceding gene: 194733945

Following gene: 194736912

Centisome position: 23.0

GC content: 57.03

Gene sequence:

>747_bases
ATGAGTTTCGTCGTCATCATTCCGGCCCGTTTTTCATCTACCCGACTGCCAGGCAAACCATTAGTGGATATTAATGGTAA
GCCCATGATTGTTCATGTCCTGGAGCGGGCGCGTGAATCTGGCGCGGAACGCATTATTGTCGCGACCGATCATGAAGACG
TGGCTCGTGCGGTAGAAGCGGCTGGCGGCGAAGTGTGCATGACGCGCGCCGATCACCAGTCCGGCACCGAACGGTTGGCG
GAAGTGGTAGAGAAGTGCGGATTCAGCGACGATACCGTTATTGTGAACGTTCAGGGCGATGAGCCGATGATCCCGGCGGT
TATTATTCGCCAGGTTGCGGAAAATCTGGCGCAGCGCCAGGTTGGCATGGCGACGTTGGCGGTGCCGATTCACAGCGCCG
AAGAAGCGTTTAACCCGAATGCGGTAAAAGTCGTGCTGGATGCTGAAGGCTATGCGCTTTACTTTTCCCGGGCGACGATT
CCCTGGGATCGCGACCGCTTTGCAAAAAGTCTGGAAACGGTAGGGGATACTTGCCTTCGTCACCTGGGCATTTACGGCTA
TCGCGCGGGATTTATCCGCCGTTACGTGAGCTGGCAACCCAGCCCGCTGGAACATATTGAAATGCTGGAGCAACTCCGTG
TGCTGTGGTACGGCGAAAAAATTCATGTCGCCGTCGCCAAAGCGGTGCCCGGCACGGGCGTAGACACCGCCGACGACCTG
GAGCGCGTACGCGCTGAAATGCGTTAA

Upstream 100 bases:

>100_bases
TAATTTGCAAACTGGATAATCTCGCTTTCCCGTTACGCGACGGCATTCCTGTATTGCTGGAAAATGAAGCTCGCTCCCTG
ACATCTGATGAGAGTAAATC

Downstream 100 bases:

>100_bases
CATGATCCTGTTCATGATCGTCTTAGACGGTCATGAACAGCGCGGTATGATAGCGCAAAGATGAATACTCACGTCTGCTC
ATCAGTGGCGGCTTTCTCGT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDL
ERVRAEMR

Sequences:

>Translated_248_residues
MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDL
ERVRAEMR
>Mature_247_residues
SFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAE
VVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATIP
WDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDLE
RVRAEMR

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=248, Percent_Identity=93.9516129032258, Blast_Score=480, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27433; Mature: 27302

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEA
CCEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
AGGEVCMTRADHQSGTERLAEVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQ
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
VGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAKSLETVGDTCLR
HCHHEEEEECCCHHHCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDL
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHH
ERVRAEMR
HHHHHHCC
>Mature Secondary Structure 
SFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEA
CEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
AGGEVCMTRADHQSGTERLAEVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQ
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
VGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAKSLETVGDTCLR
HCHHEEEEECCCHHHCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDL
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHH
ERVRAEMR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA