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The map label for this gene is pabB [H]

Identifier: 194736555

GI number: 194736555

Start: 1899178

End: 1900542

Strand: Direct

Name: pabB [H]

Synonym: SeSA_A1968

Alternate gene names: 194736555

Gene position: 1899178-1900542 (Clockwise)

Preceding gene: 194735092

Following gene: 194737033

Centisome position: 40.33

GC content: 55.16

Gene sequence:

>1365_bases
ATGATGAAGACGTTATCTCCCACTGTTATCACCTTACCCTGGCGTCCGGACGCCGCTGAACACTATTTTGCGCCCGTAAA
CCATTTGCCCTGGGCGATGCTGCTGCATTCAGGTGATGCTATTCATCCCTATAACCGCTTTGATATTCTGGTCGCCGATC
CTGTCACCACACTGACCACGCGCGCCCAGGAAACCACGGTATGTACTGCGCGCACGACTACCGTCACTCTCGACGATCCG
TTACACGTTTTGCAGACTCAACTGGAGGCGCTGCCTTTTCATCCTCAGCCTGACCCTGACTTACCCTTTCAGGGCGGCGC
GCTGGGTCTGTTTGGTTATGATTTAGGGCGGCGTTTCGAAATTCTGCCCGATACTGCTGCGCGCGATATCGTTTTACCCG
ATATGGCGATTGGCCTTTACGACTGGGCGCTGATTGTCGATCACCATAAACAGGTAGTGTCGCTGATAAGCTATCACGAT
GCAGACGCCCGATATCGCTGGCTCACCAGCCAGCTCGCGCCGACCCGCACGCCCTTCAGGCTTACCTCGGCCTGGCAATC
CAATATGACGCGTTGCGAGTATGGCGAAAAGTTTCGTCAGGTGCAGGCCTGGCTGCACAGCGGGGACTGCTATCAGGTCA
ATCTTTCCCAGCGTTTTCAGGCGAGCTACGAGGGTGATGAATGGCAGGCTTTCGAACGCCTTAACCGCGCCAATCGCGCC
CCGTTTAGCGCCTTTCTTCGTTTACATGACGGCGCCATATTGAGCCTTTCTCCCGAGCGTTTTATCCAACTGGAGAATGG
TCATATCCAGACGCGCCCGATCAAAGGTACGCTTCCACGGCTTAACGATCCGCAGGCGGATCGTCAGCAGGCGCAGAAAC
TGGCCAACTCAATAAAAGATCGCGCTGAAAATTTGATGATCGTCGATTTGATGCGTAACGATATTGGCCGGGTCGCCGTA
CCGGGTTCGGTGAAAGTGCCAGAACTGTTCGTCGTCGAACCATTTCCTGCCGTTCACCATCTGGTTAGCACCATTACCGC
CCGTTTACCGGACTCGCTTCATGCTACCGACCTGCTGCGCGCGGCTTTCCCCGGCGGCTCTATTACCGGCGCGCCTAAAG
TGCGGGCGATGGAAATTATCGACGAACTGGAGCCGCAGCGACGCAACGCCTGGTGCGGTAGCATCGGTTATCTGAGTTTC
TGCGGCAAGATGGATACCAGTATTACTATCCGCACCGTCACGGCAACGCAGGGCCAACTCTATTGCTCAGCCGGCGGCGG
TATCGTGGCCGATAGCAACGAAGAAGCGGAATATCAGGAAACTTTTGATAAAGTTAATCGTATCCTGCACCCACTGGAGA
ACTAA

Upstream 100 bases:

>100_bases
GAAGGTAAACCTGCAAACATGATTAACTCCTGCTAAATTATTAGCGCTAATTATTTCACGCTACCCGGCGGTAAGCCAGT
AGTGTTGTAACGAGTCAGGA

Downstream 100 bases:

>100_bases
TACGTGGATACCAGCCGTCTGACGCTCGATCATTTCTTATCGCGCTTTCAGCTTTTGCGCCCGCAGATGACTCATGAAAC
GTTGAATCAACGTCAGGCCG

Product: aminodeoxychorismate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MMKTLSPTVITLPWRPDAAEHYFAPVNHLPWAMLLHSGDAIHPYNRFDILVADPVTTLTTRAQETTVCTARTTTVTLDDP
LHVLQTQLEALPFHPQPDPDLPFQGGALGLFGYDLGRRFEILPDTAARDIVLPDMAIGLYDWALIVDHHKQVVSLISYHD
ADARYRWLTSQLAPTRTPFRLTSAWQSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQRFQASYEGDEWQAFERLNRANRA
PFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKGTLPRLNDPQADRQQAQKLANSIKDRAENLMIVDLMRNDIGRVAV
PGSVKVPELFVVEPFPAVHHLVSTITARLPDSLHATDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSF
CGKMDTSITIRTVTATQGQLYCSAGGGIVADSNEEAEYQETFDKVNRILHPLEN

Sequences:

>Translated_454_residues
MMKTLSPTVITLPWRPDAAEHYFAPVNHLPWAMLLHSGDAIHPYNRFDILVADPVTTLTTRAQETTVCTARTTTVTLDDP
LHVLQTQLEALPFHPQPDPDLPFQGGALGLFGYDLGRRFEILPDTAARDIVLPDMAIGLYDWALIVDHHKQVVSLISYHD
ADARYRWLTSQLAPTRTPFRLTSAWQSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQRFQASYEGDEWQAFERLNRANRA
PFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKGTLPRLNDPQADRQQAQKLANSIKDRAENLMIVDLMRNDIGRVAV
PGSVKVPELFVVEPFPAVHHLVSTITARLPDSLHATDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSF
CGKMDTSITIRTVTATQGQLYCSAGGGIVADSNEEAEYQETFDKVNRILHPLEN
>Mature_454_residues
MMKTLSPTVITLPWRPDAAEHYFAPVNHLPWAMLLHSGDAIHPYNRFDILVADPVTTLTTRAQETTVCTARTTTVTLDDP
LHVLQTQLEALPFHPQPDPDLPFQGGALGLFGYDLGRRFEILPDTAARDIVLPDMAIGLYDWALIVDHHKQVVSLISYHD
ADARYRWLTSQLAPTRTPFRLTSAWQSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQRFQASYEGDEWQAFERLNRANRA
PFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKGTLPRLNDPQADRQQAQKLANSIKDRAENLMIVDLMRNDIGRVAV
PGSVKVPELFVVEPFPAVHHLVSTITARLPDSLHATDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSF
CGKMDTSITIRTVTATQGQLYCSAGGGIVADSNEEAEYQETFDKVNRILHPLEN

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=453, Percent_Identity=76.3796909492274, Blast_Score=713, Evalue=0.0,
Organism=Escherichia coli, GI1787518, Length=404, Percent_Identity=31.4356435643564, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786809, Length=225, Percent_Identity=27.5555555555556, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=438, Percent_Identity=31.0502283105023, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=398, Percent_Identity=27.1356783919598, Blast_Score=146, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50955; Mature: 50955

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKTLSPTVITLPWRPDAAEHYFAPVNHLPWAMLLHSGDAIHPYNRFDILVADPVTTLTT
CCCCCCCCEEEECCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHC
RAQETTVCTARTTTVTLDDPLHVLQTQLEALPFHPQPDPDLPFQGGALGLFGYDLGRRFE
CCCCCEEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
ILPDTAARDIVLPDMAIGLYDWALIVDHHKQVVSLISYHDADARYRWLTSQLAPTRTPFR
ECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEE
LTSAWQSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQRFQASYEGDEWQAFERLNRANRA
EHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHCCCC
PFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKGTLPRLNDPQADRQQAQKLANSIKD
CHHHHHHHCCCEEEEECHHHEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RAENLMIVDLMRNDIGRVAVPGSVKVPELFVVEPFPAVHHLVSTITARLPDSLHATDLLR
HHCCEEEEEEHHCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHH
AAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGKMDTSITIRTVTATQGQL
HHCCCCCCCCCCCHHHHHHHHHCCCCHHCCCCCCCHHHHHHCCCCCEEEEEEEEECCCEE
YCSAGGGIVADSNEEAEYQETFDKVNRILHPLEN
EEECCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMKTLSPTVITLPWRPDAAEHYFAPVNHLPWAMLLHSGDAIHPYNRFDILVADPVTTLTT
CCCCCCCCEEEECCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHC
RAQETTVCTARTTTVTLDDPLHVLQTQLEALPFHPQPDPDLPFQGGALGLFGYDLGRRFE
CCCCCEEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
ILPDTAARDIVLPDMAIGLYDWALIVDHHKQVVSLISYHDADARYRWLTSQLAPTRTPFR
ECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEE
LTSAWQSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQRFQASYEGDEWQAFERLNRANRA
EHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHCCCC
PFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKGTLPRLNDPQADRQQAQKLANSIKD
CHHHHHHHCCCEEEEECHHHEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RAENLMIVDLMRNDIGRVAVPGSVKVPELFVVEPFPAVHHLVSTITARLPDSLHATDLLR
HHCCEEEEEEHHCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHH
AAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGKMDTSITIRTVTATQGQL
HHCCCCCCCCCCCHHHHHHHHHCCCCHHCCCCCCCHHHHHHCCCCCEEEEEEEEECCCEE
YCSAGGGIVADSNEEAEYQETFDKVNRILHPLEN
EEECCCCEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]