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The map label for this gene is sgcA [H]

Identifier: 194736405

GI number: 194736405

Start: 1676190

End: 1676627

Strand: Direct

Name: sgcA [H]

Synonym: SeSA_A1733

Alternate gene names: 194736405

Gene position: 1676190-1676627 (Clockwise)

Preceding gene: 194734161

Following gene: 194738190

Centisome position: 35.59

GC content: 57.53

Gene sequence:

>438_bases
ATGATTAATGATGTTAAGTGGGTTCAGGCGCAACGCCATGCCAGCGACTGGCGACACGCGCTGGATATCGCCGTTCGTCC
GCTGATTACCTTCGGCGCGGCGGCCCCCTGCTACCTGGACGGTATTATTGAGAACACCCTTAAATGGGGGCCATATTATC
TTATCGCGCCGGGGATTGCGCTGCCCCATGCCAGACCGGAGCAAGGCGCCAACCATAATCAAATCAGCGTCACTACGTTA
TCAACGCCGGTCGCTTTCGGCAATGCGGATTGCGATCCCATCTGGCTGTTGCTTTGCGCCAGCGCCACGGATGCCGAAGC
ACATATTCGCACCATTCAACGCATCAGCCAGTGGCTCGACTCGCCGGAAAGCGTCGCGATGCTGCAAGATGCGCCAAATG
ACGCCGCGCTTTTCGCGCAATTAACCGCATTGCGCTGA

Upstream 100 bases:

>100_bases
AGAGAGCGATAACTCTTCTGCCGATCTCCGTCGCCTTCGCCAAAAGACACGCCGGGGATCGGTTTCAGAGTAACCCGAAC
CGGCAAGGAGTCAACGATCG

Downstream 100 bases:

>100_bases
TGGAGGTTTCGATGATCCTGCACCCTTCACTGGCCTCCGCCGATCCGCTGCGCTATGCCGAGGCGTTGACCGCTTTACAC
GATGCGCCTCTCGGCTCACT

Product: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2

Products: protein histidine; sugar phosphate

Alternate protein names: Putative PTS system EIIA component [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MINDVKWVQAQRHASDWRHALDIAVRPLITFGAAAPCYLDGIIENTLKWGPYYLIAPGIALPHARPEQGANHNQISVTTL
STPVAFGNADCDPIWLLLCASATDAEAHIRTIQRISQWLDSPESVAMLQDAPNDAALFAQLTALR

Sequences:

>Translated_145_residues
MINDVKWVQAQRHASDWRHALDIAVRPLITFGAAAPCYLDGIIENTLKWGPYYLIAPGIALPHARPEQGANHNQISVTTL
STPVAFGNADCDPIWLLLCASATDAEAHIRTIQRISQWLDSPESVAMLQDAPNDAALFAQLTALR
>Mature_145_residues
MINDVKWVQAQRHASDWRHALDIAVRPLITFGAAAPCYLDGIIENTLKWGPYYLIAPGIALPHARPEQGANHNQISVTTL
STPVAFGNADCDPIWLLLCASATDAEAHIRTIQRISQWLDSPESVAMLQDAPNDAALFAQLTALR

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790755, Length=143, Percent_Identity=71.3286713286713, Blast_Score=227, Evalue=2e-61,
Organism=Escherichia coli, GI2367359, Length=125, Percent_Identity=33.6, Blast_Score=91, Evalue=3e-20,
Organism=Escherichia coli, GI1789302, Length=100, Percent_Identity=43, Blast_Score=84, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 15881; Mature: 15881

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDVKWVQAQRHASDWRHALDIAVRPLITFGAAAPCYLDGIIENTLKWGPYYLIAPGIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCEE
LPHARPEQGANHNQISVTTLSTPVAFGNADCDPIWLLLCASATDAEAHIRTIQRISQWLD
CCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCEEHEEECCCCCHHHHHHHHHHHHHHHC
SPESVAMLQDAPNDAALFAQLTALR
CCCCEEHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MINDVKWVQAQRHASDWRHALDIAVRPLITFGAAAPCYLDGIIENTLKWGPYYLIAPGIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCEE
LPHARPEQGANHNQISVTTLSTPVAFGNADCDPIWLLLCASATDAEAHIRTIQRISQWLD
CCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCEEHEEECCCCCHHHHHHHHHHHHHHHC
SPESVAMLQDAPNDAALFAQLTALR
CCCCEEHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]