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The map label for this gene is hpaX [H]

Identifier: 194736359

GI number: 194736359

Start: 1152709

End: 1154085

Strand: Direct

Name: hpaX [H]

Synonym: SeSA_A1171

Alternate gene names: 194736359

Gene position: 1152709-1154085 (Clockwise)

Preceding gene: 194736536

Following gene: 194737210

Centisome position: 24.48

GC content: 52.94

Gene sequence:

>1377_bases
ATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTCCGTTCGCACAACGCGCTCAGCACGGGTCAACAAAC
CGTCATAAATAAACTGTTCCGCCGACTGATCGTATTTTTATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACA
TCGGTTTTGCCGGGTTGACGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGCCTTGCCACGACGCTGTTTTAC
GCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGCATCGTCGGCGCCCGCCGCTGGATTGCGACCATTAT
GGTGCTATGGGGCATTGCATCTACCGCTACGATGTTCGCGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGG
GCATTACCGAAGCGGGCTTTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTTTTCCGCGCCCGCGCC
AACGCATTATTTATGATTGCCATGCCGGCCACTACCGCATTGGGGTCGATTGTCTCCGGCTATATTTTATCGCTGGACGG
CATATTCAATCTGCATGGATGGCAGTGGTTATTCCTGTTGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTGTGGT
TTTACCTGGATGATACCCCGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAGGAGATGATGGATAAT
GACCGCCTGACGCTGGTTCAGCCGGAGGGGGCTATCAGCCATAACGCCATGCAGCAGCGTAGTCTGTGGCGCGAAGTATT
CACGCCAATTGTACTGATGTATACGCTGGCCTATTTTTGCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGC
AAATCCTGAAAAGTTTTAATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCGCAGATTTGTACTATT
CTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAGCGTAAACATCACACGGCGTTGCCGTTCCTGTTTGC
CGCCGCGGGCTGGCTGCTGGCGTCGGCGACCGACCATAACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTT
CCTTTAGCGCGATGGCGATCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCGATAGGCATTGCGGTC
ATCAATGCCACCGGCAATATTGGCTCCGCACTCAGCCCATTTATGATTGGCTGGCTAAAAGATATCACCGGTAGCTTCAA
TAGCGGACTCTGGTTTGTCGCTTCTCTGTTAGTCGTCGGCGCTGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTC
CGCGCGCCACCCCTTGA

Upstream 100 bases:

>100_bases
GCTGTCCGGTGCGTCCGGCGTCTATTAAGCCTGGCCCGGTAAGCGCAGCGCTACCGGGCAACCGTAGTACCCTACAAAAA
TTCCCATCAGAGGAAAAAAA

Downstream 100 bases:

>100_bases
GGAGAAACTATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAAAGCATGGGCAGTAACGATGT
GCATTATCAGTCGTTTGCTC

Product: 4-hydroxyphenylacetate permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSDTSSALPESPESVRSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFY
ATYVIFGIPSNVMLSIVGARRWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARA
NALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDN
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTI
LGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAV
INATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP

Sequences:

>Translated_458_residues
MSDTSSALPESPESVRSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFY
ATYVIFGIPSNVMLSIVGARRWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARA
NALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDN
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTI
LGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAV
INATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP
>Mature_457_residues
SDTSSALPESPESVRSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFYA
TYVIFGIPSNVMLSIVGARRWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARAN
ALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDND
RLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTIL
GMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVI
NATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=420, Percent_Identity=30.2380952380952, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789515, Length=424, Percent_Identity=24.5283018867925, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789152, Length=453, Percent_Identity=22.7373068432671, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082320, Length=416, Percent_Identity=21.875, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI2367379, Length=462, Percent_Identity=23.5930735930736, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=420, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321698, Length=213, Percent_Identity=25.3521126760563, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=168, Percent_Identity=25, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=339, Percent_Identity=22.4188790560472, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50468; Mature: 50337

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTSSALPESPESVRSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLT
CCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGQDLGLSATMFGLATTLFYATYVIFGIPSNVMLSIVGARRWIATIMVLWGIASTATMFA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSG
ECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
YILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDN
HHHHCCCEEECCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHCC
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
EGSSNITIGLLAAIPQICTILGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHN
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLK
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHH
DITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SDTSSALPESPESVRSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLT
CCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGQDLGLSATMFGLATTLFYATYVIFGIPSNVMLSIVGARRWIATIMVLWGIASTATMFA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSG
ECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
YILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDN
HHHHCCCEEECCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHCC
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
EGSSNITIGLLAAIPQICTILGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHN
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLK
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHH
DITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]