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The map label for this gene is yegW [H]

Identifier: 194736175

GI number: 194736175

Start: 2260128

End: 2260874

Strand: Reverse

Name: yegW [H]

Synonym: SeSA_A2381

Alternate gene names: 194736175

Gene position: 2260874-2260128 (Counterclockwise)

Preceding gene: 194734564

Following gene: 194737819

Centisome position: 48.01

GC content: 53.01

Gene sequence:

>747_bases
ATGGAACAAGCGCATACCCGGCTCATCGCGCAACTGAATGAACGAATTTCAGCGGCGGATAATACGCCGCTATACATGAA
ATTCGCCCAGACGGTAAAGGATGCCGTGCGCAGCGGTATTCTTGAGCACGGTAATATTTTGCCTGGCGAACGCGATCTCA
GCCAGCTTACTGGCGTCTCGCGCATCACGGTACGAAAAGCGATGCAGGCGCTGGAAGAAGAGGGTGTCGTCACGCGCGCC
CGCGGCTACGGTACGCAAATCAATAATATCTTTGAATATTCCCTGAAAGAGGCGCGGGGATTTTCTCAGCAGGTTGTCTT
GCGCGGCAAAAAACCGGATACGCTATGGGTTAACAAACGCGTGGTAAGTTGTCCGGATGAGGTCGCGCAGCACCTGGCGA
TCCCCGCAGGCAGCGACGTCTTTTTACTCAAACGCATTCGTTATGTTGATGAGGACGCGGTATCGATTGAAGAGTCCTGG
GTGCCCGCGCATCTGATTCATGATGTCGACGCGATTGGCATTTCGTTGTATGACTATTTTCGTCGCCAGCACATTTACCC
TCAGCGTACCCGATCTCGCGTCAGCGCCCGGATGCCGGATGATGAGTTTCAGTCGCATATTCAAATGGATGGTAAAGTGC
CGGTGCTGGTGATTAAGCAGGTGGCGCTCGATCAGCAGCAGCGGCCTATTGAATACAGCATCAGTTATTGTCGTAGCGAC
CTATACGTTTTTGTGTGCGAGGAGTAG

Upstream 100 bases:

>100_bases
AGGCGGACACGCTGGAAGTGGGGAAGGGCATTGGTCCGGTACATCATTTCCACGCGTGGTGGTAGTATACTGCCTACAGA
CCCGTCGTCAGGAAAGATAA

Downstream 100 bases:

>100_bases
CGCCTCGCGTGTGGGCGCGCAGTCGCCGCCGCGATGCCCGACCACCCAGCTCGCCACCGCATTTCCCAGCAGTACGGCAT
CCGCGAGCGACCAGCCTGAC

Product: transcriptional regulator, GntR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MEQAHTRLIAQLNERISAADNTPLYMKFAQTVKDAVRSGILEHGNILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRA
RGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKRVVSCPDEVAQHLAIPAGSDVFLLKRIRYVDEDAVSIEESW
VPAHLIHDVDAIGISLYDYFRRQHIYPQRTRSRVSARMPDDEFQSHIQMDGKVPVLVIKQVALDQQQRPIEYSISYCRSD
LYVFVCEE

Sequences:

>Translated_248_residues
MEQAHTRLIAQLNERISAADNTPLYMKFAQTVKDAVRSGILEHGNILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRA
RGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKRVVSCPDEVAQHLAIPAGSDVFLLKRIRYVDEDAVSIEESW
VPAHLIHDVDAIGISLYDYFRRQHIYPQRTRSRVSARMPDDEFQSHIQMDGKVPVLVIKQVALDQQQRPIEYSISYCRSD
LYVFVCEE
>Mature_248_residues
MEQAHTRLIAQLNERISAADNTPLYMKFAQTVKDAVRSGILEHGNILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRA
RGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKRVVSCPDEVAQHLAIPAGSDVFLLKRIRYVDEDAVSIEESW
VPAHLIHDVDAIGISLYDYFRRQHIYPQRTRSRVSARMPDDEFQSHIQMDGKVPVLVIKQVALDQQQRPIEYSISYCRSD
LYVFVCEE

Specific function: Unknown

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788418, Length=248, Percent_Identity=92.3387096774193, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI87082252, Length=226, Percent_Identity=29.646017699115, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786950, Length=230, Percent_Identity=25.2173913043478, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790540, Length=214, Percent_Identity=28.0373831775701, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790118, Length=223, Percent_Identity=20.627802690583, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28331; Mature: 28331

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQAHTRLIAQLNERISAADNTPLYMKFAQTVKDAVRSGILEHGNILPGERDLSQLTGVS
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCH
RITVRKAMQALEEEGVVTRARGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKR
HHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHEEECCCCCEEEECCE
VVSCPDEVAQHLAIPAGSDVFLLKRIRYVDEDAVSIEESWVPAHLIHDVDAIGISLYDYF
EECCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RRQHIYPQRTRSRVSARMPDDEFQSHIQMDGKVPVLVIKQVALDQQQRPIEYSISYCRSD
HHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCHHCCCHHHHHHHHCCC
LYVFVCEE
EEEEEECC
>Mature Secondary Structure
MEQAHTRLIAQLNERISAADNTPLYMKFAQTVKDAVRSGILEHGNILPGERDLSQLTGVS
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCH
RITVRKAMQALEEEGVVTRARGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKR
HHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHEEECCCCCEEEECCE
VVSCPDEVAQHLAIPAGSDVFLLKRIRYVDEDAVSIEESWVPAHLIHDVDAIGISLYDYF
EECCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RRQHIYPQRTRSRVSARMPDDEFQSHIQMDGKVPVLVIKQVALDQQQRPIEYSISYCRSD
HHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCHHCCCHHHHHHHHCCC
LYVFVCEE
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]