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The map label for this gene is pyrF [H]

Identifier: 194735972

GI number: 194735972

Start: 1777973

End: 1778770

Strand: Reverse

Name: pyrF [H]

Synonym: SeSA_A1836

Alternate gene names: 194735972

Gene position: 1778770-1777973 (Counterclockwise)

Preceding gene: 194737248

Following gene: 194736552

Centisome position: 37.77

GC content: 56.64

Gene sequence:

>798_bases
ATGCACGCCGTTTATCCAATTTGCGCCACTTCCGGTGCCCATCATCAAGAAGGTCTGGTCATGACGTTTACTGCTTCATC
TTCTTCCTGCGCTATTACTGAATCGCCTGTCGTTGTGGCGTTGGATTACCATGAACGCGATAAAGCCCTGGCGTTTGTCG
ATAAAATCGATCCTCGCGATTGTCGCTTAAAAGTGGGCAAAGAGATGTTCACGTTATTTGGCCCACAGCTCGTCCGGGAT
CTCCAGCAACGTGGGTTTGATGTCTTTCTTGATCTAAAATTTCATGATATTCCCAACACCACGGCCCGGGCAGTCGCCGC
AGCGGCAGACCTGGGCGTCTGGATGGTAAACGTTCACGCGTCTGGCGGGGCGAGAATGATGGCCGCAGCGCGCGACGCGC
TGGCGCCATTCGGTAAAGATGCGCCGTTGCTCATTGCCGTGACCGTGTTGACCAGTATGGAAACCAGCGATCTGCGCGAT
CTGGGCGTGATGTTGTCACCGGCGGAACATGCGGAGCGGCTGGCGCGCCTGACGCAGCAATGCGGGCTGGATGGCGTGGT
CTGTTCCGCTCAGGAAGCGGTCAGATTTAAACAGGTCTTTGGCGCTGCATTTAAGCTGGTGACGCCGGGCATTCGGCCCG
CAGGCAGCGAGGCAGGCGATCAGCGACGCATTATGACGCCCGAACAGGCATTATCCGCCGGCGTCGACTATATGGTGATT
GGCCGCCCGGTTACGCAATCGGTAGATCCGGCGCAAACGCTGAAGGATATTAACGCGTCACTGAAACGGGAGGCATAA

Upstream 100 bases:

>100_bases
CATACTTAATGACGTAAAGCTAGAAACAACGCTGGCATCGGCGACCAAGGCTTATCAGGTTGTCAATCGAACCTGTTAAT
TTCCCTGCGCCGCAGGTAGA

Downstream 100 bases:

>100_bases
TGAGCGATTCCAATAGTCGTCTGGTTTATTCAACACAGACGGGGCGCATTGAAGAACCTAAAACGGCGCCGGTTCGTCCC
AAAGGGGATGGTATCGTTCG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MHAVYPICATSGAHHQEGLVMTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRD
LQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLRD
LGVMLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVI
GRPVTQSVDPAQTLKDINASLKREA

Sequences:

>Translated_265_residues
MHAVYPICATSGAHHQEGLVMTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRD
LQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLRD
LGVMLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVI
GRPVTQSVDPAQTLKDINASLKREA
>Mature_265_residues
MHAVYPICATSGAHHQEGLVMTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRD
LQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLRD
LGVMLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVI
GRPVTQSVDPAQTLKDINASLKREA

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=245, Percent_Identity=88.5714285714286, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 28479; Mature: 28479

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAVYPICATSGAHHQEGLVMTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRD
CCCEECCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCEEHHHCCCCCH
CRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHA
HHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEC
SGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLRDLGVMLSPAEHAERLARLTQQ
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCHHHHHHHHHEECCHHHHHHHHHHHHH
CGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVI
HCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEE
GRPVTQSVDPAQTLKDINASLKREA
CCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHAVYPICATSGAHHQEGLVMTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRD
CCCEECCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCEEHHHCCCCCH
CRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHA
HHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEC
SGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLRDLGVMLSPAEHAERLARLTQQ
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCHHHHHHHHHEECCHHHHHHHHHHHHH
CGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVI
HCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEE
GRPVTQSVDPAQTLKDINASLKREA
CCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA