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The map label for this gene is rcsA [H]

Identifier: 194735620

GI number: 194735620

Start: 2044594

End: 2045217

Strand: Direct

Name: rcsA [H]

Synonym: SeSA_A2141

Alternate gene names: 194735620

Gene position: 2044594-2045217 (Clockwise)

Preceding gene: 194735108

Following gene: 194736052

Centisome position: 43.42

GC content: 38.14

Gene sequence:

>624_bases
ATGTCAACGATTATTATGGATTTATGCAGTTACACCCGGCTAGGGTTAAGCGGGTATCTGGTCAGCAGAGGGGTGAAAAG
AAGGGAAATCAACGACATCGAAACCGTTGACGAACTCGCTATCGCTTGTGGCGCGCATCAGCCTTCGGTGGTGTTTATTA
ATGAGGACTGTTTCATCCATACGCCTTCAGACAGTCAACAAATAAAGCAAATCATTAATCAACATCCTGACACTTTATTT
ATTGTTTTTATGGCAATTGCTAATGTGCATTTTGATGAATATTTATTAGTAAGAAAAAACTTATTGATTAGCTCAAAATC
GATTAAACCTGACTCGCTGGATACCATTCTTGGCGATATTCTGAAAAAAGAGTCGGGTATTTCAGGAACCATAAATTTAC
CAACATTATCGTTAAGTCGAACTGAATCCAGCATGTTGCGAATGTGGATGGAAGGTCAGGGAACCATTCAGATTTCTGAC
AGAATGAATATTAAAGCAAAAACAGTATCCTCCCATAAGGGGAATATAAAAAGAAAGATAAAAACGCATAATAAACAAGT
TATCTATCATGTAGTACGGCTGACAGATAACGTCACTAACGGCATTTTTGTTAACATGCGCTGA

Upstream 100 bases:

>100_bases
CGCGTAAGCGTTGTCTAAGGTGACTATTCGTGTTCCGTCTGATTATGGTGAGTTATTCAGGTAAGGGGAATTATCGTTAC
GCATTGAGTGAGGGTATGCC

Downstream 100 bases:

>100_bases
GACATCCGGACTGGCAATGTACCTCCAGTCCGGCTCAATTAGTCCTGCTCCGCCTTCTCGACAAAAATACCATCCTGGTG
ACCTGACTCATTGAAGAACC

Product: colanic acid capsular biosynthesis activation protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSTIIMDLCSYTRLGLSGYLVSRGVKRREINDIETVDELAIACGAHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLF
IVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTILGDILKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISD
RMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Sequences:

>Translated_207_residues
MSTIIMDLCSYTRLGLSGYLVSRGVKRREINDIETVDELAIACGAHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLF
IVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTILGDILKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISD
RMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR
>Mature_206_residues
STIIMDLCSYTRLGLSGYLVSRGVKRREINDIETVDELAIACGAHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLFI
VFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTILGDILKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDR
MNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Specific function: Positive regulator of capsular polysaccharide synthesis. RcsA and rcsB form a complex to promote transcription of the genes for capsule synthesis [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788262, Length=207, Percent_Identity=87.9227053140097, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 23330; Mature: 23199

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIIMDLCSYTRLGLSGYLVSRGVKRREINDIETVDELAIACGAHQPSVVFINEDCFIH
CCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEE
TPSDSQQIKQIINQHPDTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTILGDI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDRMNIKAKTVSSHKGNIKRKI
HHHCCCCCEEEECCEEEECHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
STIIMDLCSYTRLGLSGYLVSRGVKRREINDIETVDELAIACGAHQPSVVFINEDCFIH
CHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEE
TPSDSQQIKQIINQHPDTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTILGDI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDRMNIKAKTVSSHKGNIKRKI
HHHCCCCCEEEECCEEEECHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626298; 11677608; 12644504 [H]