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The map label for this gene is mviN

Identifier: 194735329

GI number: 194735329

Start: 1213269

End: 1214843

Strand: Direct

Name: mviN

Synonym: SeSA_A1238

Alternate gene names: 194735329

Gene position: 1213269-1214843 (Clockwise)

Preceding gene: 194734468

Following gene: 194737837

Centisome position: 25.76

GC content: 54.41

Gene sequence:

>1575_bases
ATGCAGGAGTTTTACGCCAGGGTCTGGAATACAAAAGAAATGAATTTATTGAAATCGCTGGCTGCTGTCAGCTCGATGAC
TATGTTTTCACGCGTGTTGGGCTTTGCCCGTGATGCGATTGTCGCCAGAATTTTTGGCGCAGGGATGGCGACCGACGCCT
TTTTTGTGGCGTTTAAACTCCCCAATCTACTACGCCGGATCTTTGCCGAAGGCGCTTTTTCTCAGGCCTTTGTGCCTATC
CTGGCGGAATATAAGAGCAAGCAGGGTGAAGAAGCGACGCGGATCTTTGTCGCTTACGTTTCCGGCCTGTTGACGCTGGC
ATTGGCCGTCGTGACGGTGGCCGGTATGCTGGCCGCCCCGTGGGTGATTATGGTAACCGCGCCGGGTTTTGCCGATACTG
CGGATAAATTCGCGCTGACGACGCAACTGCTGCGGATTACGTTTCCCTATATTCTGCTGATCTCGCTGGCTTCACTGGTT
GGCGCCATTCTCAACACCTGGAATCGCTTCTCCATTCCCGCTTTTGCGCCGACATTTCTTAATATCAGCATGATCGGTTT
TGCATTATTCGCCGCGCCATACTTTAATCCGCCGGTGCTGGCGTTAGCCTGGGCAGTCACCGTCGGCGGCGTGCTGCAAC
TGGTGTATCAACTTCCGTATTTGAAAAAGATCGGTATGTTGGTGCTGCCGCGCATTAACTTTCGCGACACCGGGGCGATG
CGGGTGGTCAAACAGATGGGGCCGGCGATTTTGGGCGTATCCGTCAGTCAGATCTCCCTTATCATCAATACCATTTTTGC
CTCGTTTCTGGCCTCCGGCTCGGTCTCATGGATGTACTATGCCGATCGGTTGATGGAGTTCCCGTCCGGCGTGCTGGGCG
TGGCATTGGGGACCATCCTGTTGCCGTCATTGTCGAAAAGCTTTGCCAGCGGCAATCATGATGAGTACTGCCGCCTGATG
GACTGGGGGCTGCGTTTGTGCTTTTTACTGGCGTTGCCGAGCGCGGTAGCGTTAGGCATTCTGGCGAAGCCGCTGACGGT
CTCGCTGTTTCAGTACGGTAAATTCACCGCCTTTGATGCGGCAATGACGCAGCGGGCGTTAATCGCCTATTCGGTGGGGC
TGATTGGCTTGATCGTCGTAAAAGTGCTGGCCCCGGGCTTCTATTCTCGCCAGGATATTAAAACGCCGGTGAAAATCGCC
ATCGTGACGTTAATCATGACGCAGTTAATGAACCTGGCGTTTATTGGACCGCTGAAACACGCCGGGCTGTCGCTCTCTAT
TGGTCTGGCGGCATGTCTCAATGCGTCGCTGCTGTACTGGCAACTGCGCAAACAGAATATCTTTACGCCACAACCGGGCT
GGATGTGGTTCCTGATGCGTCTGATCATTTCCGTACTGGTGATGGCCGCCGTATTGTTCGGCGTGTTGCATATTATGCCG
GAGTGGTCGCAAGGGTCGATGCTATGGCGTTTGCTACGTTTGATGGCGGTAGTGATCGCGGGTATCGCGGCCTATTTCGC
CGCGCTTGCCGTGCTGGGCTTTAAAGTGAAAGAGTTTGTTCGCCGGACGGCGTAA

Upstream 100 bases:

>100_bases
GGAGTCTGTAAGGCCTGATAAGACGTTTTAACGTCGCCGTCAGGCGCGGTGATACAGCCGGATACGGCAGAAGTTGCGTT
ATCCGGTCGATGGATCAGCC

Downstream 100 bases:

>100_bases
ATTCAGTGCCTGATAGCGCTGTGCTATCAGGCCTACAAGGCATTCAGGCCGGAAAGGCGCAACGTCGCCATCCGGCACTG
ATTAGATAGAAATTTTTTTA

Product: integral membrane protein MviN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MQEFYARVWNTKEMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPI
LAEYKSKQGEEATRIFVAYVSGLLTLALAVVTVAGMLAAPWVIMVTAPGFADTADKFALTTQLLRITFPYILLISLASLV
GAILNTWNRFSIPAFAPTFLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPYLKKIGMLVLPRINFRDTGAM
RVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYCRLM
DWGLRLCFLLALPSAVALGILAKPLTVSLFQYGKFTAFDAAMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIA
IVTLIMTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQNIFTPQPGWMWFLMRLIISVLVMAAVLFGVLHIMP
EWSQGSMLWRLLRLMAVVIAGIAAYFAALAVLGFKVKEFVRRTA

Sequences:

>Translated_524_residues
MQEFYARVWNTKEMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPI
LAEYKSKQGEEATRIFVAYVSGLLTLALAVVTVAGMLAAPWVIMVTAPGFADTADKFALTTQLLRITFPYILLISLASLV
GAILNTWNRFSIPAFAPTFLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPYLKKIGMLVLPRINFRDTGAM
RVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYCRLM
DWGLRLCFLLALPSAVALGILAKPLTVSLFQYGKFTAFDAAMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIA
IVTLIMTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQNIFTPQPGWMWFLMRLIISVLVMAAVLFGVLHIMP
EWSQGSMLWRLLRLMAVVIAGIAAYFAALAVLGFKVKEFVRRTA
>Mature_524_residues
MQEFYARVWNTKEMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPI
LAEYKSKQGEEATRIFVAYVSGLLTLALAVVTVAGMLAAPWVIMVTAPGFADTADKFALTTQLLRITFPYILLISLASLV
GAILNTWNRFSIPAFAPTFLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPYLKKIGMLVLPRINFRDTGAM
RVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYCRLM
DWGLRLCFLLALPSAVALGILAKPLTVSLFQYGKFTAFDAAMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIA
IVTLIMTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQNIFTPQPGWMWFLMRLIISVLVMAAVLFGVLHIMP
EWSQGSMLWRLLRLMAVVIAGIAAYFAALAVLGFKVKEFVRRTA

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family

Homologues:

Organism=Escherichia coli, GI1787309, Length=510, Percent_Identity=94.3137254901961, Blast_Score=941, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): MVIN_SALTY (P37169)

Other databases:

- EMBL:   Z26133
- EMBL:   D25292
- EMBL:   AE006468
- PIR:   S40271
- RefSeq:   NP_460141.1
- GeneID:   1252688
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1170
- HOGENOM:   HBG731814
- OMA:   MLKITFP
- ProtClustDB:   CLSK2301989
- BioCyc:   STYP99287:STM1170-MONOMER
- GO:   GO:0009405
- InterPro:   IPR004268
- PRINTS:   PR01806
- TIGRFAMs:   TIGR01695

Pfam domain/function: PF03023 MVIN

EC number: NA

Molecular weight: Translated: 57316; Mature: 57316

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1dc0b934)-; HASH(0x1e4393c0)-; HASH(0x1d4e6ed8)-; HASH(0x1e4623c0)-; HASH(0x1e432ab4)-; HASH(0x1e38a3d4)-; HASH(0x1dee52a8)-; HASH(0x1e370eb0)-; HASH(0x1e3e8f1c)-; HASH(0x1bdc2590)-; HASH(0x1e432bd4)-; HASH(0x1e432ca0)-; HASH(0x1e06c8b0)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEFYARVWNTKEMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKL
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
PNLLRRIFAEGAFSQAFVPILAEYKSKQGEEATRIFVAYVSGLLTLALAVVTVAGMLAAP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WVIMVTAPGFADTADKFALTTQLLRITFPYILLISLASLVGAILNTWNRFSIPAFAPTFL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
NISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPYLKKIGMLVLPRINFRDTGAM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHH
RVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTIL
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LPSLSKSFASGNHDEYCRLMDWGLRLCFLLALPSAVALGILAKPLTVSLFQYGKFTAFDA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLIMTQLMNLAFIGPLKH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
AGLSLSIGLAACLNASLLYWQLRKQNIFTPQPGWMWFLMRLIISVLVMAAVLFGVLHIMP
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
EWSQGSMLWRLLRLMAVVIAGIAAYFAALAVLGFKVKEFVRRTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQEFYARVWNTKEMNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKL
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
PNLLRRIFAEGAFSQAFVPILAEYKSKQGEEATRIFVAYVSGLLTLALAVVTVAGMLAAP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WVIMVTAPGFADTADKFALTTQLLRITFPYILLISLASLVGAILNTWNRFSIPAFAPTFL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
NISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPYLKKIGMLVLPRINFRDTGAM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHH
RVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTIL
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LPSLSKSFASGNHDEYCRLMDWGLRLCFLLALPSAVALGILAKPLTVSLFQYGKFTAFDA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLIMTQLMNLAFIGPLKH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
AGLSLSIGLAACLNASLLYWQLRKQNIFTPQPGWMWFLMRLIISVLVMAAVLFGVLHIMP
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
EWSQGSMLWRLLRLMAVVIAGIAAYFAALAVLGFKVKEFVRRTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609