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The map label for this gene is papD [H]

Identifier: 194735172

GI number: 194735172

Start: 3091949

End: 3092692

Strand: Reverse

Name: papD [H]

Synonym: SeSA_A3197

Alternate gene names: 194735172

Gene position: 3092692-3091949 (Counterclockwise)

Preceding gene: 194734483

Following gene: 291084496

Centisome position: 65.68

GC content: 58.87

Gene sequence:

>744_bases
GTGAAAAACAGCAGAAGAAGCCGTGTGATTTTACTCGCGCTGGCGGCAGCATGGAGCCAGTGCAGCCCGGCGGCCGTCAA
TGTCGACCGGACCCGTATTATCATGGATGCGCCGCAGAAAACGGTGGCCATCACGCTGAATAACGATGACAAAACCACGC
CGTTCCTGGCGCAGTCCTGGGTGACGGATGCTGACGGGGTGAGAACGGATGCGCTGATGGCGCTGCCGCCGCTGCAGCGT
ATTGATGCCGGACAGAAATCTCAGGTCCGCATTACCCAGGTTCGTGGGCTGACAGATAAGCTCCCTCAGGACAGGGAAAC
ACTGTTCTGGTTTAACGTGCGGGGCGTTCCCCCGAAGCCGGAAGACGACAACGTCCTGCAGCTGGCCATGCAGAGTCAGC
TGAAACTGTTTTACCGTCCGAAAGCCATTATCAGAAGCAGCAGTGACCAGCCGGAAAGAAAGCTGACCGCTGAGCGGAAT
GCGGGACACCTGACCCTCAGAAACCCGACGCCGTACTACATCACTGTGGCGTGGCTGGGAGCAGACCGTAGCCACAGGCT
CAGCGGTTTCCGCGAGGGCGTGATGGTGCCGCCCCTGGGGAGCCTGCCTTTAAAGGCTGTTCTGCCAGCAGAAACCCGGA
CGCTGTGGGTAGGGTATATTGATGATTACGGTGGACTGCAGATGAATCGCTACGCCTGCGATGCCCTGAACTGCGCGTTT
AAGGACGCAGGGGCGACATCATGA

Upstream 100 bases:

>100_bases
CTCACCCTGCCGGAAACGGTGACACTCAGTCGGGGGCCGCTGTTACTGCCCTGCAGATAAAAATATCCCTGTCACAGAGC
AGGACTAACGGAGAAAACAG

Downstream 100 bases:

>100_bases
CAGGACGATTATTCAATATGAAATCACTGATACTGTCAGGTGTGTTTCTTTTCTTTGCTGTCTGTGATTCTGCGAGGGCA
AACTATGACTGGTCAAAATG

Product: pili assembly chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKNSRRSRVILLALAAAWSQCSPAAVNVDRTRIIMDAPQKTVAITLNNDDKTTPFLAQSWVTDADGVRTDALMALPPLQR
IDAGQKSQVRITQVRGLTDKLPQDRETLFWFNVRGVPPKPEDDNVLQLAMQSQLKLFYRPKAIIRSSSDQPERKLTAERN
AGHLTLRNPTPYYITVAWLGADRSHRLSGFREGVMVPPLGSLPLKAVLPAETRTLWVGYIDDYGGLQMNRYACDALNCAF
KDAGATS

Sequences:

>Translated_247_residues
MKNSRRSRVILLALAAAWSQCSPAAVNVDRTRIIMDAPQKTVAITLNNDDKTTPFLAQSWVTDADGVRTDALMALPPLQR
IDAGQKSQVRITQVRGLTDKLPQDRETLFWFNVRGVPPKPEDDNVLQLAMQSQLKLFYRPKAIIRSSSDQPERKLTAERN
AGHLTLRNPTPYYITVAWLGADRSHRLSGFREGVMVPPLGSLPLKAVLPAETRTLWVGYIDDYGGLQMNRYACDALNCAF
KDAGATS
>Mature_247_residues
MKNSRRSRVILLALAAAWSQCSPAAVNVDRTRIIMDAPQKTVAITLNNDDKTTPFLAQSWVTDADGVRTDALMALPPLQR
IDAGQKSQVRITQVRGLTDKLPQDRETLFWFNVRGVPPKPEDDNVLQLAMQSQLKLFYRPKAIIRSSSDQPERKLTAERN
AGHLTLRNPTPYYITVAWLGADRSHRLSGFREGVMVPPLGSLPLKAVLPAETRTLWVGYIDDYGGLQMNRYACDALNCAF
KDAGATS

Specific function: Binds and caps interactive surfaces on pilus subunits to prevent them from participating in non-productive interactions. Facilitates the import of subunits into the periplasm. May facilitate subunit folding. Chaperone-subunit complexes are then targeted t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786936, Length=216, Percent_Identity=39.8148148148148, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1788677, Length=217, Percent_Identity=36.8663594470046, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87082203, Length=248, Percent_Identity=37.0967741935484, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790771, Length=221, Percent_Identity=37.5565610859729, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1789532, Length=228, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786333, Length=188, Percent_Identity=35.1063829787234, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787171, Length=220, Percent_Identity=30.4545454545455, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786743, Length=175, Percent_Identity=30.2857142857143, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788428, Length=209, Percent_Identity=30.1435406698565, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87081806, Length=216, Percent_Identity=30.0925925925926, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 27477; Mature: 27477

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSRRSRVILLALAAAWSQCSPAAVNVDRTRIIMDAPQKTVAITLNNDDKTTPFLAQSW
CCCCCCCEEEEEEEEHHHCCCCCCEEECCCEEEEEECCCEEEEEEECCCCCCCCHHHHHH
VTDADGVRTDALMALPPLQRIDAGQKSQVRITQVRGLTDKLPQDRETLFWFNVRGVPPKP
CCCCCCCCCCEEEECCCHHHHCCCCCCCEEEEEECCCHHHCCCCCCEEEEEEECCCCCCC
EDDNVLQLAMQSQLKLFYRPKAIIRSSSDQPERKLTAERNAGHLTLRNPTPYYITVAWLG
CCCHHHHHHHHHHHHEEECCHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCEEEEEEEEC
ADRSHRLSGFREGVMVPPLGSLPLKAVLPAETRTLWVGYIDDYGGLQMNRYACDALNCAF
CCCCHHHHHHHCCEECCCCCCCCCEEECCCCCEEEEEEEEECCCCEEECHHHHHHHHHHC
KDAGATS
CCCCCCC
>Mature Secondary Structure
MKNSRRSRVILLALAAAWSQCSPAAVNVDRTRIIMDAPQKTVAITLNNDDKTTPFLAQSW
CCCCCCCEEEEEEEEHHHCCCCCCEEECCCEEEEEECCCEEEEEEECCCCCCCCHHHHHH
VTDADGVRTDALMALPPLQRIDAGQKSQVRITQVRGLTDKLPQDRETLFWFNVRGVPPKP
CCCCCCCCCCEEEECCCHHHHCCCCCCCEEEEEECCCHHHCCCCCCEEEEEEECCCCCCC
EDDNVLQLAMQSQLKLFYRPKAIIRSSSDQPERKLTAERNAGHLTLRNPTPYYITVAWLG
CCCHHHHHHHHHHHHEEECCHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCEEEEEEEEC
ADRSHRLSGFREGVMVPPLGSLPLKAVLPAETRTLWVGYIDDYGGLQMNRYACDALNCAF
CCCCHHHHHHHCCEECCCCCCCCCEEECCCCCEEEEEEEEECCCCEEECHHHHHHHHHHC
KDAGATS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1357526; 10049807; 2478891; 10446050 [H]