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The map label for this gene is dcp [H]

Identifier: 194735134

GI number: 194735134

Start: 1557149

End: 1559191

Strand: Direct

Name: dcp [H]

Synonym: SeSA_A1615

Alternate gene names: 194735134

Gene position: 1557149-1559191 (Clockwise)

Preceding gene: 194737678

Following gene: 194737855

Centisome position: 33.07

GC content: 53.84

Gene sequence:

>2043_bases
ATGTCGACGAATCCTTTGTTAGACCAGAGTATGTTGCCTTATCAGGCACCGCGTTTTGATCGGATCAAAGATTGCCATTA
TCGTCCTGCTTTTGATGAGGGCGTGCGGCAAAAACGCGTGGAAATCGAGGCCATCGTCAATCATCCGGCGGCCCCTGATT
TTACGAATACGCTTCTGGCGCTGGAGCAAAGCGGGGCGCTTCTGTCACGCGTCACCAGCGTTTTTTTCGCGATGACGGCC
GCGCACACTAACGATGAACTCCAGCGGTTGGATGAGGCCTTTTCTGCCGAGCTGGCGGCGCTCTCCAACGATATTTATCT
GAATAGCGCGTTATTCGCTCGCGTGGATGCCGTCTGGCAACAGCGTCACTCACTGGGGCTGGATGATGAGTCGCTACGGT
TGGTCGATGTGATCCATCAGCGTTTTGTGTTGGCAGGTGCGCAGCTTGCCGAAGAGGATAAAGCGCGACTGAAGGTATTG
AATACTGAATCCGCGACCTTAATGAGTCAGTTTAATCAGCGTCTGCTGGCGGCAAGTAAAGCGGGCGGGCTGGCGGTCGA
TGACGCGCATTGCCTGGCAGGATTAAGCCCGGAAGAAATGACCGTCGCTGCTGAAGCGGCGCGTGAAAAAGGCCTGGAGG
AGCGCTGGTTCATTCCGCTCCTTAATACGACGCAACAGCCTGCGCTTGCTACACTGCGCGATCGCCAGACTCGCGAAAAT
TTATTCGCAGCGTCATGGACTCGGGCGGAAAAAGGAGATGCCCACGATACCCGCGCTATCGTTCAGCGTCTGGTAGAGAT
TCGTCGCTGTCAGGCAAAACTGCTGGGTTTCCCCAATTATGCCGCATGGAAAATGGCCGATCAGATGGCGAAAACGCCGC
AAGCCGCACTGAGCTTTATGCGTGGCATTGTGCCGCCAGCGCGTCAGCGCGTACTCAATGAACAGGCGGAAATTCAGAAC
GTCATTGATGGTGAGCAGGGCGGCTACACCGTTCAGGCCTGGGACTGGATGTTCTATGCCGAACAGGTACGGCGGGAAAA
ATATGCGTTAGATGAAGCGCAACTGAAGCCCTATTTTGCCTTAAATACGGTGTTACAAGAGGGGGTTTTCTGGACCGCCA
ACCAGCTATTCGGCATCACCTTCGTCGAGCGTTTTGACATTCCGGTGTACCACCCTGATGTTCGGGTGTGGGAGATTTTC
GACTCCGATGGTGTCGGCATGGCGTTATTTTATGGCGACTTCTTCGCGCGGGACTCGAAAAGCGGCGGCGCGTGGATGGG
GAATTTTGTCGAGCAATCCACACTCAACGAAACCCGGCCCGTTATATACAATGTTTGTAACTATCAGAAACCGGTTGATG
GGCAGCCTGCATTACTGCTTTGGGACGACGTTATTACGCTCTTCCATGAGTTTGGTCATACGCTACATGGTTTGTTTGCC
GTCCAACGCTATGCCACGCTTTCAGGTACCAATACGCCCCGCGACTTTGTTGAGTTTCCCTCCCAGATTAATGAGCATTG
GGCGAGCCATCCGCGTGTGTTCGAACGCTACGCGCGTCATGTCGACAGCGGTGAAAAAATGCCTGCTGATTTACAGGAAA
GAATGCGCAAGGCGAGTTTATTTAATAAAGGTTACGATATGACTGAATTGCTCGGCGCCGCATTGCTGGATATGCGCTGG
CATATGCTGGAGGAGAGCGTAGCAGAGCAGTCTGTCGCTGAGTTCGAGCAGCAGGCGCTGGCCGCCGAGCATCTTGATTT
ACCGGCAGTGCCGCCCCGCTATCGCAGCAGTTATTTTGCCCATATCTTCGGCGGCGGCTACGCAGCGGGATACTACGCCT
ACCTGTGGACGCAAATGTTAGCGGATGACGGTTATCAATGGTTTGTAGAGCAGGGCGGCCTGACGCGTGAAAACGGGCAG
CGTTTTCGTGATGCTATCCTTTCCCGGGGGAATAGTACTGATTTAGAAACGCTTTATTCAGCCTGGCGTGGACATGAACC
GCATATTGACCCCATGTTACAATATCGTGGGCTCGATCGCTAA

Upstream 100 bases:

>100_bases
AGCACGCGGCGTTTATGAAAGGGTAATCCTGGTTAACACGGTTGCGGTCAGCATAGGGGGAAGCTTACTCTTATGATCAA
CCTATTTTCAGGAGTGAAAA

Downstream 100 bases:

>100_bases
GCTGATACGGTTGTTCGGCACTGTCGAACAACCGCCTGAAAATGAATCCTGCACTTCTGATGACAGCCAGTTAAATTTAT
GGGGTTAAATTGTCTGAATA

Product: dipeptidyl carboxypeptidase II

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTA
AHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVL
NTESATLMSQFNQRLLAASKAGGLAVDDAHCLAGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQN
VIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIF
DSDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELLGAALLDMRW
HMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQ
RFRDAILSRGNSTDLETLYSAWRGHEPHIDPMLQYRGLDR

Sequences:

>Translated_680_residues
MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTA
AHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVL
NTESATLMSQFNQRLLAASKAGGLAVDDAHCLAGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQN
VIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIF
DSDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELLGAALLDMRW
HMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQ
RFRDAILSRGNSTDLETLYSAWRGHEPHIDPMLQYRGLDR
>Mature_679_residues
STNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTAA
HTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVLN
TESATLMSQFNQRLLAASKAGGLAVDDAHCLAGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTRENL
FAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQNV
IDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFALNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIFD
SDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFAV
QRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELLGAALLDMRWH
MLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQR
FRDAILSRGNSTDLETLYSAWRGHEPHIDPMLQYRGLDR

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=603, Percent_Identity=26.6998341625207, Blast_Score=195, Evalue=9e-50,
Organism=Homo sapiens, GI14149738, Length=554, Percent_Identity=27.7978339350181, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI156105687, Length=650, Percent_Identity=22.6153846153846, Blast_Score=144, Evalue=3e-34,
Organism=Escherichia coli, GI1787819, Length=678, Percent_Identity=79.0560471976401, Blast_Score=1090, Evalue=0.0,
Organism=Escherichia coli, GI1789913, Length=685, Percent_Identity=32.5547445255474, Blast_Score=338, Evalue=5e-94,
Organism=Saccharomyces cerevisiae, GI6319793, Length=660, Percent_Identity=24.6969696969697, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6322715, Length=447, Percent_Identity=23.0425055928412, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21356111, Length=571, Percent_Identity=24.3432574430823, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI20129717, Length=397, Percent_Identity=25.6926952141058, Blast_Score=119, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 77278; Mature: 77147

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLA
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LEQSGALLSRVTSVFFAMTAAHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQ
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
QRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVLNTESATLMSQFNQRLLAASK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHC
AGGLAVDDAHCLAGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
CCCCEECCHHHHCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHH
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFM
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHH
RGIVPPARQRVLNEQAEIQNVIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFA
HHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCHHHH
LNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIFDSDGVGMALFYGDFFARDSK
HHHHHHCCCEEEHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEEHHHHHHCCCC
SGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
CCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASL
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FNKGYDMTELLGAALLDMRWHMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEE
HIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQRFRDAILSRGNSTDLETLYS
HHHCCCHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
AWRGHEPHIDPMLQYRGLDR
HHCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
STNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEAIVNHPAAPDFTNTLLA
CCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LEQSGALLSRVTSVFFAMTAAHTNDELQRLDEAFSAELAALSNDIYLNSALFARVDAVWQ
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
QRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVLNTESATLMSQFNQRLLAASK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHC
AGGLAVDDAHCLAGLSPEEMTVAAEAAREKGLEERWFIPLLNTTQQPALATLRDRQTREN
CCCCEECCHHHHCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHHHHHHH
LFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLGFPNYAAWKMADQMAKTPQAALSFM
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHH
RGIVPPARQRVLNEQAEIQNVIDGEQGGYTVQAWDWMFYAEQVRREKYALDEAQLKPYFA
HHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCHHHH
LNTVLQEGVFWTANQLFGITFVERFDIPVYHPDVRVWEIFDSDGVGMALFYGDFFARDSK
HHHHHHCCCEEEHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCEEEEEHHHHHHCCCC
SGGAWMGNFVEQSTLNETRPVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFA
CCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VQRYATLSGTNTPRDFVEFPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASL
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FNKGYDMTELLGAALLDMRWHMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEE
HIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQRFRDAILSRGNSTDLETLYS
HHHCCCHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
AWRGHEPHIDPMLQYRGLDR
HHCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537804; 11677609 [H]