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The map label for this gene is chbR [H]

Identifier: 194735027

GI number: 194735027

Start: 1360649

End: 1361491

Strand: Direct

Name: chbR [H]

Synonym: SeSA_A1412

Alternate gene names: 194735027

Gene position: 1360649-1361491 (Clockwise)

Preceding gene: 194737684

Following gene: 194735432

Centisome position: 28.89

GC content: 43.3

Gene sequence:

>843_bases
ATGATGCAGCTACAGGTTAACGCAACGGAAATCAAAACGGTTTATGAGCAGCAGCTCTTCAATGGCAAAAATTTCCATGT
GTTTATCTATAACAAGACGGAAAGCGTCACCGGGCTGCATCAGCACGACTACTATGAATTTACCCTGGTATTAACCGGAC
GTTATTACCAGGAGATCAACGGGAAGCGTGTGCTGCTGGAACGTGGAGATTTTGTTTTTATCCCGGTGGGGTCGAATCAC
CAAAGTTTCTATGAGTTTGGCGCAACGCGTATTCTGAACGTAGGAATTAGTAAACGTTTTTTTGAACAGCATTATCTTCC
GTTACTGCCGTTTTGTTTTGTGGCATCGCAGGTATACAGGGCGAATAGCACCTTCCTTACCTATATTGAAACGGTGATTG
CGTCGTTGAATTTTCGCGGCAATGGGCTCGACGAATTTATCGAAGTGGTGACATTTTATATTATAAACCGCTTACGTCAT
TACCGCGAAGAGCAGGTTTATGATGATATTCCACAATGGCTGAAAGCAACCGTGGAGATAATGCATGATAAAACGCAGTT
TGGCGAACATGCGCTGGAAAATATGGTGCGCCTGTCGGCAAAATCCCAGGAGTATCTGACGCGCGCCACCCGACGTTATT
ACAGCAAAACGCCGATGCAAATCATTAATGAGATTCGCATTAATTTTGCCAAGAAACAGTTGGAAATGACCAACTATTCG
GTTACGGATATTGCTTATGAAGCCGGGTATAGCAGTCCAAGTCTGTTTATTAAAACGTTTAAGAAGATGACCTCATTCAC
ACCGAATAGTTATCGGAAGCGATTGACGGAAATTAATGAGTAA

Upstream 100 bases:

>100_bases
CTGGTTCACGCTCAGGATCATTTGATGACCTCAATGCTGGCTCGTGAACTGATCGCTGAGTTGATTGAGCTCCATGAGAA
ACTGAAATAACAGGGGGCGG

Downstream 100 bases:

>100_bases
CGGTTTACATTGCTCGATTAGTTACATTTCACGCTTGCCCCAATAGCGCGGGGAACGTCACGCTATTTCTTACGAGCGGG
CATAGCGTAATACATATCAG

Product: DNA-binding transcriptional regulator ChbR

Products: NA

Alternate protein names: Chb operon repressor [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MMQLQVNATEIKTVYEQQLFNGKNFHVFIYNKTESVTGLHQHDYYEFTLVLTGRYYQEINGKRVLLERGDFVFIPVGSNH
QSFYEFGATRILNVGISKRFFEQHYLPLLPFCFVASQVYRANSTFLTYIETVIASLNFRGNGLDEFIEVVTFYIINRLRH
YREEQVYDDIPQWLKATVEIMHDKTQFGEHALENMVRLSAKSQEYLTRATRRYYSKTPMQIINEIRINFAKKQLEMTNYS
VTDIAYEAGYSSPSLFIKTFKKMTSFTPNSYRKRLTEINE

Sequences:

>Translated_280_residues
MMQLQVNATEIKTVYEQQLFNGKNFHVFIYNKTESVTGLHQHDYYEFTLVLTGRYYQEINGKRVLLERGDFVFIPVGSNH
QSFYEFGATRILNVGISKRFFEQHYLPLLPFCFVASQVYRANSTFLTYIETVIASLNFRGNGLDEFIEVVTFYIINRLRH
YREEQVYDDIPQWLKATVEIMHDKTQFGEHALENMVRLSAKSQEYLTRATRRYYSKTPMQIINEIRINFAKKQLEMTNYS
VTDIAYEAGYSSPSLFIKTFKKMTSFTPNSYRKRLTEINE
>Mature_280_residues
MMQLQVNATEIKTVYEQQLFNGKNFHVFIYNKTESVTGLHQHDYYEFTLVLTGRYYQEINGKRVLLERGDFVFIPVGSNH
QSFYEFGATRILNVGISKRFFEQHYLPLLPFCFVASQVYRANSTFLTYIETVIASLNFRGNGLDEFIEVVTFYIINRLRH
YREEQVYDDIPQWLKATVEIMHDKTQFGEHALENMVRLSAKSQEYLTRATRRYYSKTPMQIINEIRINFAKKQLEMTNYS
VTDIAYEAGYSSPSLFIKTFKKMTSFTPNSYRKRLTEINE

Specific function: Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presen

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788030, Length=280, Percent_Identity=85.7142857142857, Blast_Score=509, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013096
- InterPro:   IPR011051
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF07883 Cupin_2; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33135; Mature: 33135

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQLQVNATEIKTVYEQQLFNGKNFHVFIYNKTESVTGLHQHDYYEFTLVLTGRYYQEIN
CEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECHHHHHCC
GKRVLLERGDFVFIPVGSNHQSFYEFGATRILNVGISKRFFEQHYLPLLPFCFVASQVYR
CCEEEEECCCEEEEEECCCCHHHHHHHHHHEECCCHHHHHHHHHCHHHHHHHHHHHHHHH
ANSTFLTYIETVIASLNFRGNGLDEFIEVVTFYIINRLRHYREEQVYDDIPQWLKATVEI
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHDKTQFGEHALENMVRLSAKSQEYLTRATRRYYSKTPMQIINEIRINFAKKQLEMTNYS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
VTDIAYEAGYSSPSLFIKTFKKMTSFTPNSYRKRLTEINE
HHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MMQLQVNATEIKTVYEQQLFNGKNFHVFIYNKTESVTGLHQHDYYEFTLVLTGRYYQEIN
CEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECHHHHHCC
GKRVLLERGDFVFIPVGSNHQSFYEFGATRILNVGISKRFFEQHYLPLLPFCFVASQVYR
CCEEEEECCCEEEEEECCCCHHHHHHHHHHEECCCHHHHHHHHHCHHHHHHHHHHHHHHH
ANSTFLTYIETVIASLNFRGNGLDEFIEVVTFYIINRLRHYREEQVYDDIPQWLKATVEI
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHDKTQFGEHALENMVRLSAKSQEYLTRATRRYYSKTPMQIINEIRINFAKKQLEMTNYS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
VTDIAYEAGYSSPSLFIKTFKKMTSFTPNSYRKRLTEINE
HHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 9405618 [H]