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The map label for this gene is tdk [H]

Identifier: 194735022

GI number: 194735022

Start: 1823389

End: 1824006

Strand: Reverse

Name: tdk [H]

Synonym: SeSA_A1883

Alternate gene names: 194735022

Gene position: 1824006-1823389 (Counterclockwise)

Preceding gene: 194735711

Following gene: 194738267

Centisome position: 38.73

GC content: 48.71

Gene sequence:

>618_bases
ATGGCACAGCTATATTTCTACTATTCGGCAATGAATGCGGGTAAGTCGACTGCACTGCTGCAATCTTCATACAATTATCA
GGAACGCGGGATGCGTACCGTCGTATATACGGCGGAAATCGACGATCGTTTCGGCGCAGGCAAAGTCAGCTCTCGTATCG
GTTTGTCGTCGCCGGCAAAATTGTTTAACCAAAATACATCCTTGTTTGAAGAGATTCGTGCCGAGAGCGCGCGGCAGACA
ATACATTGCGTGTTAGTCGACGAAAGCCAGTTTTTGACTCGCCAGCAGGTTTATCAATTATCCGAGGTTGTCGACAAATT
AGATATTCCAGTACTCTGCTATGGGCTACGAACAGACTTTCGTGGGGAACTCTTTGTCGGCAGCCAATACTTGCTGGCAT
GGTCAGATAAGCTGGTGGAATTAAAAACTATCTGTTTCTGCGGTCGTAAAGCCAGTATGGTTCTGCGACTTGATCAGGAC
GGCAGGCCTTATAACGAAGGCGAACAGGTGGTTATTGGCGGGAATGAACGCTACGTTTCAGTTTGCCGTAAGCATTATAA
GGACGCGCTGGAGGAGGGCTCACTGACGGCGATTCAGGAGCGTCATCGGCACATATGA

Upstream 100 bases:

>100_bases
ATTCTTAATACTCACCGGAGCGCGAGCCGCGCCGTCGCGTCGGTAAATTATGGTACAATCCCGCCAATCTTTATTTCACT
CAGGTGAGGTCCTGCGACCA

Downstream 100 bases:

>100_bases
TACCCGAGGTAGCGATGGCTTATAAAACGCCCTGTAGCGCTTTGGACGTCATTATTCAGGCCTCCTGACGAAGGGCGTGC
CGTGAGTGCGTAGGCCAGAT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAKLFNQNTSLFEEIRAESARQT
IHCVLVDESQFLTRQQVYQLSEVVDKLDIPVLCYGLRTDFRGELFVGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQD
GRPYNEGEQVVIGGNERYVSVCRKHYKDALEEGSLTAIQERHRHI

Sequences:

>Translated_205_residues
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAKLFNQNTSLFEEIRAESARQT
IHCVLVDESQFLTRQQVYQLSEVVDKLDIPVLCYGLRTDFRGELFVGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQD
GRPYNEGEQVVIGGNERYVSVCRKHYKDALEEGSLTAIQERHRHI
>Mature_204_residues
AQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAKLFNQNTSLFEEIRAESARQTI
HCVLVDESQFLTRQQVYQLSEVVDKLDIPVLCYGLRTDFRGELFVGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQDG
RPYNEGEQVVIGGNERYVSVCRKHYKDALEEGSLTAIQERHRHI

Specific function: Phosphorylates both thymidine and deoxyuridine [H]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=204, Percent_Identity=92.6470588235294, Blast_Score=395, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 23405; Mature: 23274

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAK
CCEEEEEEEECCCCCCHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHH
LFNQNTSLFEEIRAESARQTIHCVLVDESQFLTRQQVYQLSEVVDKLDIPVLCYGLRTDF
HHCCCHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
RGELFVGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQDGRPYNEGEQVVIGGNERYVS
CCEEEECCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHH
VCRKHYKDALEEGSLTAIQERHRHI
HHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure 
AQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAK
CEEEEEEEECCCCCCHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHH
LFNQNTSLFEEIRAESARQTIHCVLVDESQFLTRQQVYQLSEVVDKLDIPVLCYGLRTDF
HHCCCHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
RGELFVGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQDGRPYNEGEQVVIGGNERYVS
CCEEEECCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHH
VCRKHYKDALEEGSLTAIQERHRHI
HHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10222209; 11206551; 11258796 [H]