Click here to switch to the map view.

The map label for this gene is marC [H]

Identifier: 194734616

GI number: 194734616

Start: 1565651

End: 1566316

Strand: Direct

Name: marC [H]

Synonym: SeSA_A1626

Alternate gene names: 194734616

Gene position: 1565651-1566316 (Clockwise)

Preceding gene: 194734417

Following gene: 194737448

Centisome position: 33.25

GC content: 53.45

Gene sequence:

>666_bases
ATGATGGATTTGTTTAAAGCGATTGGATTGGGGCTGGTCGTACTGCTCCCGTTAGCCAATCCGCTAACCACCGTGGCGCT
GTTTCTTGGCCTTGCGGGCAATATGAATAGTGCGGAACGCAACCGGCAGTCCTATATGGCTTCGGTTTATGTCTTCGCTA
TTATGATGGTGGCGTACTATGCCGGGCAGTTAGTCATGAACACCTTCGGTATTTCGATTCCAGGGCTACGGATCGCCGGG
GGGTTAATCGTGGCGTTTATCGGCTTCAGAATGCTTTTCCCGCAGCAGAAGGCGCATGAGTCGCCGGAAGCGAAAAGCAA
ATCGGAGGAGCTGGCAGACGAACCGACGGCCAATATTGCGTTTGTTCCACTGGCTATGCCAAGCACCGCAGGACCGGGGA
CCATCGCAATGATCATCAGTTCCGCTTCCACGGTGCGTCATGGCGGCGAGTTTCCCGACTGGGTCATTATGGTCGCGCCG
CCGATTATTTTTCTTGCCGTGGCGGTGATCCTGTGGGGATGCTTACGCAGTTCTGGCGCTATTATGCGGCTGGTGGGGAA
AGGGGGGATTGAAGCGATCTCCCGCTTAATGGGATTCCTGCTGGTGTGTATGGGCGTGCAATTTATTATCAACGGCGTGT
TGGAAATTATTAAAACGTACCACTAA

Upstream 100 bases:

>100_bases
TGTAGAGGATATTAATTTGCACACTGGCGAAATGGCGCGCCTGGGCAATTTCACTTTATACTTCCGGTTCATGAAACGCT
GATGGGTAAGAGATAGTATT

Downstream 100 bases:

>100_bases
GGCGCATTTTCGTCTGCCGGAAACCTGTTCCCGGCAGACGAATGTCTTAATGCGGTTGTTCTTCCAGCGTCACTGGCCAT
TTGCGGAATATGAGCACAGC

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSYMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAHESPEAKSKSEELADEPTANIAFVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAP
PIIFLAVAVILWGCLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH

Sequences:

>Translated_221_residues
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSYMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAHESPEAKSKSEELADEPTANIAFVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAP
PIIFLAVAVILWGCLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
>Mature_221_residues
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSYMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAHESPEAKSKSEELADEPTANIAFVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAP
PIIFLAVAVILWGCLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=221, Percent_Identity=91.8552036199095, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1787494, Length=199, Percent_Identity=30.6532663316583, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789842, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 23608; Mature: 23608

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSYMASVYVFAIMMVAYY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHESPEAKSKSEELADEPTANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAPPIIFLAVAVILWGCLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCH
IMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
HEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSYMASVYVFAIMMVAYY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHESPEAKSKSEELADEPTANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAPPIIFLAVAVILWGCLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCH
IMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
HEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA