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The map label for this gene is lolC [H]

Identifier: 194734536

GI number: 194734536

Start: 1267324

End: 1268523

Strand: Direct

Name: lolC [H]

Synonym: SeSA_A1294

Alternate gene names: 194734536

Gene position: 1267324-1268523 (Clockwise)

Preceding gene: 194735613

Following gene: 194735840

Centisome position: 26.91

GC content: 55.25

Gene sequence:

>1200_bases
ATGTATCAACCTGTCGCTCTATTCATTGGCCTGCGTTACATGCGCGGGCGTGCAGCAGATCGCTTCGGTCGCTTCGTTTC
CTGGCTTTCCACTATCGGCATTACCCTGGGGGTGATGGCGCTGGTCACGGTATTGTCGGTGATGAACGGTTTTGAGCGCG
AACTGCAAAATAACATTCTTGGTTTGATGCCTCAGGCCATCCTCTCTGCTGAACATGGTTCTCTTAACCCGAATCAGATG
CCGGAAAAAGCGGTGAATCTGCAAGGCGTTAACCGTATTGCGCCGCTGACGACGGGCGATGTCGTACTGCAAAGCGCGCG
TAGCGTTGCGGTTGGCGTGATGTTGGGTATCGATCCGGCGCAAAAAGATCCGTTAACGCCGTATCTGGTCAATGTGAAGC
AAAGCGAATTACAGCCGGGTAAGTATAATGTCATCCTCGGCGAGCAGCTCGCCGGACAGTTAGGGGTCAACCGCGGCGAT
CAGATTCGGCTAATGGTGCCATCTGCCAGCCAGTTTACGCCAATGGGACGTCTGCCCAGCCAGCGTCTGTTTACGGTGAT
TGGCACATTTGCCGCCAATAGCGAGGTCGATGGCTATGAAATGCTGGTCAATATTCAGGACGCATCGCGTTTAATGCGCT
ATCCGGCAGGCAATATTACCGGCTGGCGTCTGTGGCTGGATGAACCGCTGCAAGTCGATACCCTCAGCCAACAGACGCTG
CCGCAAGGCACGAAGTGGCAGGACTGGCGCGAACGTAAAGGCGAGTTGTTCCAGGCTGTGCGCATGGAAAAGAACATGAT
GGGATTGTTGCTGAGCCTCATCGTGGCGGTCGCGGCTTTTAACATTATTACTTCGTTGGGTCTGATGGTCATGGAGAAGC
AGGGCGAAGTGGCGATTTTACAAACTCAAGGGCTGACGCCGCGACAAATTATGATGGTCTTTATGGTGCAGGGTGCCAGC
GCCGGGATTATCGGCGCGCTGTTGGGCGCCGCGCTGGGCGCATTGCTTGCCAGCCAACTGAATAACCTGATGCCGATCAT
CGGCGCGTTTCTGGATGGCGCTGCGTTGCCCGTGGCGATAGAGCCGTTACAGGTGATCGTTATCGCTCTGGTGGCAATGG
CCATCGCGCTGCTTTCTACGCTTTATCCTTCCTGGCGCGCTGCCGCCACTCAACCCGCTGAGGCTTTACGTTATGAATAA

Upstream 100 bases:

>100_bases
TTTCAGAATAACGCTGACGAACTCTTACGGTTCAGACATTTACGCATTCCGCTTTCGCTTATATACTCGGGACTTTGCTA
ACAGCAACCAGACGGATTAC

Downstream 100 bases:

>100_bases
GATCCTGTTGCAATGCGACAACCTGTGCAAACGCTATCAGGAAGGCACCGTACAAACCGACGTGTTGCACGATGTCAGCT
TCAGTATCGGCGAAGGCGAA

Product: outer membrane-specific lipoprotein transporter subunit LolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSAEHGSLNPNQM
PEKAVNLQGVNRIAPLTTGDVVLQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQSELQPGKYNVILGEQLAGQLGVNRGD
QIRLMVPSASQFTPMGRLPSQRLFTVIGTFAANSEVDGYEMLVNIQDASRLMRYPAGNITGWRLWLDEPLQVDTLSQQTL
PQGTKWQDWRERKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGAS
AGIIGALLGAALGALLASQLNNLMPIIGAFLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE

Sequences:

>Translated_399_residues
MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSAEHGSLNPNQM
PEKAVNLQGVNRIAPLTTGDVVLQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQSELQPGKYNVILGEQLAGQLGVNRGD
QIRLMVPSASQFTPMGRLPSQRLFTVIGTFAANSEVDGYEMLVNIQDASRLMRYPAGNITGWRLWLDEPLQVDTLSQQTL
PQGTKWQDWRERKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGAS
AGIIGALLGAALGALLASQLNNLMPIIGAFLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE
>Mature_399_residues
MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSAEHGSLNPNQM
PEKAVNLQGVNRIAPLTTGDVVLQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQSELQPGKYNVILGEQLAGQLGVNRGD
QIRLMVPSASQFTPMGRLPSQRLFTVIGTFAANSEVDGYEMLVNIQDASRLMRYPAGNITGWRLWLDEPLQVDTLSQQTL
PQGTKWQDWRERKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGAS
AGIIGALLGAALGALLASQLNNLMPIIGAFLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=399, Percent_Identity=93.734335839599, Blast_Score=723, Evalue=0.0,
Organism=Escherichia coli, GI1787362, Length=417, Percent_Identity=27.0983213429257, Blast_Score=134, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43282; Mature: 43282

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMPQAILSAEHGSLNPNQMPEKAVNLQGVNRIAPLTTGDVVLQSARSVAVGVMLGIDPA
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHEEHEECCCCC
QKDPLTPYLVNVKQSELQPGKYNVILGEQLAGQLGVNRGDQIRLMVPSASQFTPMGRLPS
CCCCCCCEEECCCHHHCCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCH
QRLFTVIGTFAANSEVDGYEMLVNIQDASRLMRYPAGNITGWRLWLDEPLQVDTLSQQTL
HHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHC
PQGTKWQDWRERKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEE
QTQGLTPRQIMMVFMVQGASAGIIGALLGAALGALLASQLNNLMPIIGAFLDGAALPVAI
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEH
EPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHCCC
>Mature Secondary Structure
MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMPQAILSAEHGSLNPNQMPEKAVNLQGVNRIAPLTTGDVVLQSARSVAVGVMLGIDPA
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHEEHEECCCCC
QKDPLTPYLVNVKQSELQPGKYNVILGEQLAGQLGVNRGDQIRLMVPSASQFTPMGRLPS
CCCCCCCEEECCCHHHCCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCH
QRLFTVIGTFAANSEVDGYEMLVNIQDASRLMRYPAGNITGWRLWLDEPLQVDTLSQQTL
HHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHC
PQGTKWQDWRERKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEE
QTQGLTPRQIMMVFMVQGASAGIIGALLGAALGALLASQLNNLMPIIGAFLDGAALPVAI
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEH
EPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]