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The map label for this gene is ansP [H]

Identifier: 194734462

GI number: 194734462

Start: 1641395

End: 1642888

Strand: Direct

Name: ansP [H]

Synonym: SeSA_A1702

Alternate gene names: 194734462

Gene position: 1641395-1642888 (Clockwise)

Preceding gene: 194738314

Following gene: 194735947

Centisome position: 34.86

GC content: 53.35

Gene sequence:

>1494_bases
ATGAAAACACAGACTACGCACGCCGCAGAACAACATGCGGCGAAACGACGCTGGCTGAACGCCCATGAAGAGGGGTATCA
CAAAGCGATGGGGAATCGTCAGGTTCAGATGATTGCTATCGGCGGCGCGATTGGCACCGGTTTATTTTTAGGTGCAGGCG
CCCGATTGCAAATGGCCGGACCGGCACTGGCGCTGGTCTATCTGATATGTGGCATTTTTTCTTTTTTCATTTTACGCGCG
CTGGGCGAACTGGTATTGCATCGCCCTTCCAGCGGGAGTTTCGTCTCCTACGCCCGTGAATTTTTGGGTGAAAAAGCGGC
CTACGTCGCAGGCTGGATGTACTTTATTAACTGGGCGATGACCGGGATCGTCGATATCACCGCAGTGGCGTTATACATGC
ACTACTGGGGCGCATTTGGCGACGTTCCGCAATGGGTGTTCGCGCTCGGCGCGTTAACCATTGTCGGTACCATGAACATG
ATCGGCGTAAAATGGTTTGCCGAAATGGAGTTCTGGTTCGCGCTGATAAAAGTACTCGCCATTGTTATCTTCCTGGTGGT
AGGCACGATTTTTCTCGGTACCGGTCAACCGCTTGAGGGTAATGCCACCGGTTTTCACCTGATTACAGATAATGGCGGCT
TTTTCCCGCACGGCCTGTTGCCCGCGCTGGTACTGATTCAGGGCGTAGTGTTCGCCTTTGCGTCGATTGAACTGGTCGGT
ACCGCCGCTGGGGAGTGCAAAGATCCACAGACGATGGTGCCAAAAGCCATCAATAGCGTGATCTGGCGTATTGGTCTTTT
CTATGTAGGATCGGTCGTATTGCTGGTTTTGCTGCTGCCGTGGAACGCCTACCAGGCGGGGCAAAGTCCGTTTGTCACCT
TCTTTTCTAAACTTGGCGTGCCTTATATCGGCAGTATTATGAATATCGTGGTGTTAACCGCCGCGCTTTCCAGCCTGAAC
TCCGGGCTTTACTGTACGGGGAGAATTTTACGTTCAATGTCGATGGGGGGTTCCGCGCCGAAATTCATGGCGAAAATGAG
CCGTCAGCATGTGCCCTATGCGGGTATTCTGGCGACTCTGGTGGTTTACGTGGTCGGCGTATTCCTGAATTACCTGGTCC
CCTCCCGCGTGTTTGAGATCGTTCTTAATTTTGCCTCGCTCGGCATTATCGCGTCGTGGGCGTTTATCATGGTGTGCCAG
ATGCGTTTACGCCAGGCGATAAAAGAAGGCAAAGCCGCAGACGTCAGTTTTAAACTGCCCGGCGCGCCTTTTACCTCCTG
GCTAACACTGCTGTTTTTACTAAGCGTGCTGGTACTCATGGCGTTTGACTACCCGAATGGAACTTACACTATCGCCTCGT
TGCCGCTGATCGCCATTCTGCTGGTCGCCGGCTGGTTTGGCGTGCGACGTCGTGTGGCGGAGATCCATCGCACTGCGCCA
GTGACGGCGGATTCGACAGATAGTGTCGTATTGAAAGAAGAAGCAGCGACATAA

Upstream 100 bases:

>100_bases
CAGGGAAAAGCGGCATTCGCCATTGCAGGCAATCGATTGGTGAGCGCCCGTCGCGGCATAAGGAATTTTTCTGTCAGGAC
AGGCTATAACAGGTAACGTA

Downstream 100 bases:

>100_bases
CATTACCCTTCCCCGGCAGCCCCAGGCCTGCCGGGTTTAATGCGCGTTACCGCCAACACCGCATCGCGCCCAATGCTTAG
TCAGCCTTAATCAACTGCGC

Product: L-asparagine permease

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
TAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLN
SGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQ
MRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
VTADSTDSVVLKEEAAT

Sequences:

>Translated_497_residues
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
TAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLN
SGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQ
MRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
VTADSTDSVVLKEEAAT
>Mature_497_residues
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
TAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLN
SGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQ
MRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
VTADSTDSVVLKEEAAT

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=429, Percent_Identity=22.8438228438228, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI258645169, Length=413, Percent_Identity=21.5496368038741, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110347453, Length=402, Percent_Identity=22.636815920398, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI258614005, Length=414, Percent_Identity=21.0144927536232, Blast_Score=66, Evalue=9e-11,
Organism=Homo sapiens, GI258614003, Length=414, Percent_Identity=21.0144927536232, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI87081915, Length=499, Percent_Identity=91.3827655310621, Blast_Score=904, Evalue=0.0,
Organism=Escherichia coli, GI1786302, Length=446, Percent_Identity=38.1165919282511, Blast_Score=315, Evalue=6e-87,
Organism=Escherichia coli, GI1786789, Length=461, Percent_Identity=37.3101952277657, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1790653, Length=459, Percent_Identity=36.8191721132898, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1786602, Length=453, Percent_Identity=37.3068432671082, Blast_Score=304, Evalue=8e-84,
Organism=Escherichia coli, GI48994972, Length=421, Percent_Identity=38.9548693586698, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI87081708, Length=453, Percent_Identity=33.7748344370861, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1789017, Length=440, Percent_Identity=32.9545454545455, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1788480, Length=395, Percent_Identity=34.1772151898734, Blast_Score=232, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17532491, Length=437, Percent_Identity=21.9679633867277, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17533459, Length=447, Percent_Identity=23.489932885906, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=455, Percent_Identity=22.4175824175824, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=448, Percent_Identity=30.5803571428571, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6320772, Length=438, Percent_Identity=30.8219178082192, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6322892, Length=431, Percent_Identity=33.4106728538283, Blast_Score=186, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324990, Length=498, Percent_Identity=27.5100401606426, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324924, Length=440, Percent_Identity=29.3181818181818, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324059, Length=466, Percent_Identity=29.8283261802575, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6321629, Length=428, Percent_Identity=28.9719626168224, Blast_Score=163, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6321053, Length=427, Percent_Identity=26.6978922716628, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6324553, Length=399, Percent_Identity=29.8245614035088, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322967, Length=423, Percent_Identity=28.1323877068558, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319543, Length=426, Percent_Identity=28.169014084507, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320717, Length=416, Percent_Identity=28.125, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324981, Length=423, Percent_Identity=28.3687943262411, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319824, Length=414, Percent_Identity=27.536231884058, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320251, Length=433, Percent_Identity=26.7898383371824, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319608, Length=449, Percent_Identity=25.6124721603563, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319542, Length=405, Percent_Identity=27.1604938271605, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666159, Length=437, Percent_Identity=21.5102974828375, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221512776, Length=437, Percent_Identity=21.5102974828375, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=23.3100233100233, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=23.3100233100233, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=23.3100233100233, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53964; Mature: 53964

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAG
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEECC
PALALVYLICGIFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNMIGVKWFAEMEFWFALIKVLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
VVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQMRLRQAIKEGKAADVSFKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTADSTDSVVLKEEAAT
CCCCCCCCEEECCCCCC
>Mature Secondary Structure
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAG
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEECC
PALALVYLICGIFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNMIGVKWFAEMEFWFALIKVLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
VVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQMRLRQAIKEGKAADVSFKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTADSTDSVVLKEEAAT
CCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]