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The map label for this gene is sinR

Identifier: 194734026

GI number: 194734026

Start: 349555

End: 350502

Strand: Direct

Name: sinR

Synonym: SeSA_A0342

Alternate gene names: 194734026

Gene position: 349555-350502 (Clockwise)

Preceding gene: 194736448

Following gene: 194734828

Centisome position: 7.42

GC content: 39.45

Gene sequence:

>948_bases
ATGATGGAACTGATCAATAATCGTGGTATGCGAGACTGGATGATATTTATTAAAGTGGCGGAAGTAGGGAATCTTTCCCG
GGCTGCACGGGAATTAGATATTAGCATTTCTGCTGTCAGTAAATCGCTTAGTCGCCTTGAGAATTCTATTGAGGTTACTT
TACTTCGGCGCGATTCACATCACTTAGAACTGACTGGAGCTGGTCAGACAGCCTATGCAAGCATGAAAAGGATAACATCT
TCCTTTCAGTCCTTGCTGGATGAATTGCGAAATCCGGATAAAATTATCAGAGGGAGTATAAAATTTTCGGCTCCGGCTAT
TGTCTGTGAGTTTCTTGCCAATAAGTGGATATGGGAATTTACAGCTAGCTATCCGGATACAAAAATCTACCTGGATTCAC
GAGAGCGTAGCGATTTTTTTAGTAAATCCCTGGAGTTTGATGAGCTGGTTTTTAAAAGTGGCATAATCGAAAGTGAGGAT
CTCGTGTATCGAAAGATAAGCCCTTTAAAGTTGGTTCTTTGTGCGAGTCCGAAATATATTAGAAAATATGGCAGGATCTC
ACATCCTGGCGATTTGGAAAATCACATTATTGTGGGTCTTCACAACCATGGTCTTTCCGGACCTCTTACTCTTTTCCGTC
AAGATGAATCATACACTATTAGTGGCGCTGTTAATGTTCATTTATCTTCCAATAATCTTTTGAGTGTTCTTAATTTGGTT
TTAGAAGGAAAGGGTATCAACCTCATGACTCCGGCCTGGCTTGCCACCAAATACTTAAAAAATAATGAACTTGAAATTAT
ACTTCCTGAATGGAGGGTCCCAGATCTCCCCATTTATCTTGTATGGCGTCATCGTCAGTATTATTCTCCTTTATTTCAAC
GCTTTCTGTCTTTTATTGAAGATAAATGGAATAATCGCCCACAAATTGATTTTCTGAATGATGATTAA

Upstream 100 bases:

>100_bases
TTATTATGATGATATCAAGGACATTGAGGCACACAATGACGCATCAGTAAGTCGTTGATAGCTCCTTTAATATAAGAATT
TCTTTTATCAACGGAAGATA

Downstream 100 bases:

>100_bases
CCCGTTTGGAATGGTTTTGACACGTTCCTGACTTAAACCCACATGATGATGGATGATGACTGAATTGAGGCATCGAGATA
TGCGACTGGTCAGCCAGTCG

Product: LysR-family transcriptional regulator SinR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITS
SFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESED
LVYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQDESYTISGAVNVHLSSNNLLSVLNLV
LEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD

Sequences:

>Translated_315_residues
MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITS
SFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESED
LVYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQDESYTISGAVNVHLSSNNLLSVLNLV
LEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD
>Mature_315_residues
MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITS
SFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESED
LVYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQDESYTISGAVNVHLSSNNLLSVLNLV
LEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD

Specific function: Probable regulatory protein. Its target is not known

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787128, Length=307, Percent_Identity=28.6644951140065, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789639, Length=280, Percent_Identity=22.1428571428571, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789440, Length=302, Percent_Identity=26.4900662251656, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=24.8322147651007, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081978, Length=268, Percent_Identity=25, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): SINR_SALTY (P37459)

Other databases:

- EMBL:   L04307
- EMBL:   AE006468
- PIR:   A47269
- RefSeq:   NP_459302.1
- ProteinModelPortal:   P37459
- PRIDE:   P37459
- GeneID:   1251823
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM0304
- HOGENOM:   HBG673981
- OMA:   RIESEDL
- ProtClustDB:   CLSK893927
- BioCyc:   STYP99287:STM0304-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 36324; Mature: 36324

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSH
CCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
HLELTGAGQTAYASMKRITSSFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEF
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHCCEEEEE
TASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDLVYRKISPLKLVLCASPKYI
ECCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCHHEEECCCEEEEEECCCHHH
RKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQDESYTISGAVNVHLSSNNLLSVLNLV
HHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEEEEEEECCCCHHHHHHHH
LEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIE
HCCCCCCEECHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
DKWNNRPQIDFLNDD
HHCCCCCCEEECCCC
>Mature Secondary Structure
MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSH
CCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
HLELTGAGQTAYASMKRITSSFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEF
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHCCEEEEE
TASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDLVYRKISPLKLVLCASPKYI
ECCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCHHEEECCCEEEEEECCCHHH
RKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQDESYTISGAVNVHLSSNNLLSVLNLV
HHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEEEEEEECCCCHHHHHHHH
LEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIE
HCCCCCCEECHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
DKWNNRPQIDFLNDD
HHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8430070; 11677609