Click here to switch to the map view.

The map label for this gene is exbB

Identifier: 194733979

GI number: 194733979

Start: 3225389

End: 3226123

Strand: Reverse

Name: exbB

Synonym: SeSA_A3342

Alternate gene names: 194733979

Gene position: 3226123-3225389 (Counterclockwise)

Preceding gene: 194734327

Following gene: 194736731

Centisome position: 68.51

GC content: 55.1

Gene sequence:

>735_bases
GTGGGTAATAATTTGATGCAGACGGATCTCTCCGTCTGGGGTATGTATCAGCACGCCGATATTGTCGTGAAGTGCGTGAT
GATTGGTCTGATTCTGGCGTCAGTCGTCACCTGGGCTATCTTCTTCAGTAAAAGTGTTGAATTTTTCACTCAAAAGCGCC
GCTTAAAGCGCGAACAACTGCAATTAGCCGATGCGCGCTCTTTAGATCAGGCTTCTGACATTGCGGCAGGTTTCAGCGCA
AAAAGCCTCAGCGCACAGCTCATCAATGAAGCGCAGAATGAACTGGAACTCTCTCAGGGCAGCGAAGATAACGAAGGGAT
TAAAGAACGTACCGGCTTCCGTCTGGAACGTCGCGTCGCTGCGGTTGGCCGCTACATGGGACGAGGCAACGGTTATCTGG
CGACGATCGGCGCCATTTCCCCCTTCGTCGGGTTGTTTGGCACCGTATGGGGCATTATGAATAGCTTCATCGGTATTGCG
CAAACGCAGACCACCAACCTGGCGGTGGTTGCTCCTGGTATTGCGGAAGCGCTGCTGGCGACGGCGATTGGGCTGGTAGC
CGCGATCCCGGCGGTCGTCATTTACAACATCTTCGCACGTCAGATAGGCAGTTACAAAGCAACGCTGGGCGACGTGGCGG
CGCAGGTATTGCTGCTGCAAAGCCGCGATCTCGATCTGAATGCGAGCGCCAGTGCGCAGCCGGTACGCGCCGCGCAGAAA
TTACGGGTAGGGTAA

Upstream 100 bases:

>100_bases
GTGCGGCAGTATGTAAATAGTAATGAGAACGACTATCAATTCGACGTCGTTTTGATATTATTATGCTCAGATTTTGTGAT
TTGCGTCCTGGAGATACAGA

Downstream 100 bases:

>100_bases
TGCGTCATGGCAATGCGTCTTAACGAGAACCTGGATGACAACGGCGAAATGCATGAAATCAACGTGACGCCGTTTATCGA
TGTCATGTTGGTTCTGCTGA

Product: biopolymer transport protein ExbB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSKSVEFFTQKRRLKREQLQLADARSLDQASDIAAGFSA
KSLSAQLINEAQNELELSQGSEDNEGIKERTGFRLERRVAAVGRYMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNIFARQIGSYKATLGDVAAQVLLLQSRDLDLNASASAQPVRAAQK
LRVG

Sequences:

>Translated_244_residues
MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSKSVEFFTQKRRLKREQLQLADARSLDQASDIAAGFSA
KSLSAQLINEAQNELELSQGSEDNEGIKERTGFRLERRVAAVGRYMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNIFARQIGSYKATLGDVAAQVLLLQSRDLDLNASASAQPVRAAQK
LRVG
>Mature_243_residues
GNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSKSVEFFTQKRRLKREQLQLADARSLDQASDIAAGFSAK
SLSAQLINEAQNELELSQGSEDNEGIKERTGFRLERRVAAVGRYMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIAQ
TQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNIFARQIGSYKATLGDVAAQVLLLQSRDLDLNASASAQPVRAAQKL
RVG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family

Homologues:

Organism=Escherichia coli, GI1789381, Length=244, Percent_Identity=89.7540983606557, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1786958, Length=210, Percent_Identity=33.8095238095238, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EXBB_SALTI (P0A1H8)

Other databases:

- EMBL:   AL627277
- EMBL:   AE014613
- RefSeq:   NP_457552.1
- RefSeq:   NP_806764.1
- PRIDE:   P0A1H8
- GeneID:   1071497
- GeneID:   1249601
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t3079
- KEGG:   sty:STY3332
- HOGENOM:   HBG681852
- OMA:   DDNNGIK
- ProtClustDB:   PRK10414
- BioCyc:   SENT209261:T3079-MONOMER
- BioCyc:   SENT220341:STY3332-MONOMER
- InterPro:   IPR002898
- InterPro:   IPR014164
- TIGRFAMs:   TIGR02797

Pfam domain/function: PF01618 MotA_ExbB

EC number: NA

Molecular weight: Translated: 26180; Mature: 26048

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20da6594)-; HASH(0x21d26190)-; HASH(0x217c2498)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSKSVEFFTQKRRLKREQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLADARSLDQASDIAAGFSAKSLSAQLINEAQNELELSQGSEDNEGIKERTGFRLERRVA
HHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHH
AVGRYMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIAQTQTTNLAVVAPGIAEALLA
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
TAIGLVAAIPAVVIYNIFARQIGSYKATLGDVAAQVLLLQSRDLDLNASASAQPVRAAQK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LRVG
HCCH
>Mature Secondary Structure 
GNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSKSVEFFTQKRRLKREQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLADARSLDQASDIAAGFSAKSLSAQLINEAQNELELSQGSEDNEGIKERTGFRLERRVA
HHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHH
AVGRYMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIAQTQTTNLAVVAPGIAEALLA
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
TAIGLVAAIPAVVIYNIFARQIGSYKATLGDVAAQVLLLQSRDLDLNASASAQPVRAAQK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LRVG
HCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504