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The map label for this gene is pabC [H]

Identifier: 194733938

GI number: 194733938

Start: 1246447

End: 1247256

Strand: Direct

Name: pabC [H]

Synonym: SeSA_A1274

Alternate gene names: 194733938

Gene position: 1246447-1247256 (Clockwise)

Preceding gene: 194735687

Following gene: 194735901

Centisome position: 26.47

GC content: 54.2

Gene sequence:

>810_bases
ATGTATCTGATTAACGGCCAATCCACTGAACGACTCGCGGTGAATGACCGGGGGGTGCAGTTCGGAGACGGTTGCTTTAC
CACTGCGCGGATCGCGGCGGGGGAGATTGCCTTGTTTTCCCGTCATCTGGCTCGCCTGGAAGAAACGTGCTCTCGTTTGG
CGATCCCCTTTAACGATTGGGATGTATTAGTAAAAGAGATGCGCAGCCTGGCACAACCGCATCGGGAAGGCGTGCTGAAA
GTGATGATTACCCGCGGCGCAGGCGGACGCGGTTACAGCGCCGCCAGTTGTCAATTACCCACACGGATTCTTAGCGTGTC
GCCTTACCCTGCCCACTACGCCCGCTGGAAAGACGAGGGCATCACTCTTACCCTTAGTCCCATACCGCTTGGGCGCAATC
CTTATCTTGCCGGATTAAAACATCTGAACCGCCTCGAACAGGTGTTGATTCGCTCTCATCTTGAGCAGACGGACGCCGAT
GAGGCGCTGGTTCTTGACAGCGAGGGATGGGTTACGGAATGCTGTGCGGCTAATTTGTTCTGGCGTACAGGCGACATTGT
TTTTACGCCGCGTCTGGATCAGGCCGGGGTGAACGGCATTATGCGACAATTTTGTTTACGCCAACTGGCGCAATCTCCTT
TCCAGGTTCTTGAAGTACAGGCGAGAGAGGAGGCAGTCAGGCAGGCGGATGAGATTATCATCTGCAACGCGCTAATGCCG
ATTATTCCCATACGCGCCTATCACGGGACGTCGTATTCTTCGCGAACACTGTTTCAATTTTTAGCCCCATTTTGTGAGCA
TCCGAATTAG

Upstream 100 bases:

>100_bases
AATAAGGAAAACCTGATAAATAACGTGTTATCTTGCTGGCAAAGTCCTTGCGCGCAGGCCATTCCCCTGGCACTCTGATG
GGCGGTTATCTGGAGGATGA

Downstream 100 bases:

>100_bases
TTATGAAAAAATTGTCAGGCGTTTTCCTTCTGCTGTTGGTTGTGCTGGGTATTGCCGCGGGCGTGGGGTTGTGGAAAGTT
CGCCATCTGGCGAACAGCAC

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MYLINGQSTERLAVNDRGVQFGDGCFTTARIAAGEIALFSRHLARLEETCSRLAIPFNDWDVLVKEMRSLAQPHREGVLK
VMITRGAGGRGYSAASCQLPTRILSVSPYPAHYARWKDEGITLTLSPIPLGRNPYLAGLKHLNRLEQVLIRSHLEQTDAD
EALVLDSEGWVTECCAANLFWRTGDIVFTPRLDQAGVNGIMRQFCLRQLAQSPFQVLEVQAREEAVRQADEIIICNALMP
IIPIRAYHGTSYSSRTLFQFLAPFCEHPN

Sequences:

>Translated_269_residues
MYLINGQSTERLAVNDRGVQFGDGCFTTARIAAGEIALFSRHLARLEETCSRLAIPFNDWDVLVKEMRSLAQPHREGVLK
VMITRGAGGRGYSAASCQLPTRILSVSPYPAHYARWKDEGITLTLSPIPLGRNPYLAGLKHLNRLEQVLIRSHLEQTDAD
EALVLDSEGWVTECCAANLFWRTGDIVFTPRLDQAGVNGIMRQFCLRQLAQSPFQVLEVQAREEAVRQADEIIICNALMP
IIPIRAYHGTSYSSRTLFQFLAPFCEHPN
>Mature_269_residues
MYLINGQSTERLAVNDRGVQFGDGCFTTARIAAGEIALFSRHLARLEETCSRLAIPFNDWDVLVKEMRSLAQPHREGVLK
VMITRGAGGRGYSAASCQLPTRILSVSPYPAHYARWKDEGITLTLSPIPLGRNPYLAGLKHLNRLEQVLIRSHLEQTDAD
EALVLDSEGWVTECCAANLFWRTGDIVFTPRLDQAGVNGIMRQFCLRQLAQSPFQVLEVQAREEAVRQADEIIICNALMP
IIPIRAYHGTSYSSRTLFQFLAPFCEHPN

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=269, Percent_Identity=65.7992565055762, Blast_Score=380, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30114; Mature: 30114

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLINGQSTERLAVNDRGVQFGDGCFTTARIAAGEIALFSRHLARLEETCSRLAIPFNDW
CEEECCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DVLVKEMRSLAQPHREGVLKVMITRGAGGRGYSAASCQLPTRILSVSPYPAHYARWKDEG
HHHHHHHHHHHCHHHCCEEEEEEECCCCCCCCCCCCCCCCHHHEECCCCCHHHHHCCCCC
ITLTLSPIPLGRNPYLAGLKHLNRLEQVLIRSHLEQTDADEALVLDSEGWVTECCAANLF
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHE
WRTGDIVFTPRLDQAGVNGIMRQFCLRQLAQSPFQVLEVQAREEAVRQADEIIICNALMP
EECCCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEHHHHHH
IIPIRAYHGTSYSSRTLFQFLAPFCEHPN
HHEEEEECCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYLINGQSTERLAVNDRGVQFGDGCFTTARIAAGEIALFSRHLARLEETCSRLAIPFNDW
CEEECCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DVLVKEMRSLAQPHREGVLKVMITRGAGGRGYSAASCQLPTRILSVSPYPAHYARWKDEG
HHHHHHHHHHHCHHHCCEEEEEEECCCCCCCCCCCCCCCCHHHEECCCCCHHHHHCCCCC
ITLTLSPIPLGRNPYLAGLKHLNRLEQVLIRSHLEQTDADEALVLDSEGWVTECCAANLF
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHE
WRTGDIVFTPRLDQAGVNGIMRQFCLRQLAQSPFQVLEVQAREEAVRQADEIIICNALMP
EECCCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEHHHHHH
IIPIRAYHGTSYSSRTLFQFLAPFCEHPN
HHEEEEECCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]