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The map label for this gene is yrbG [C]

Identifier: 194333035

GI number: 194333035

Start: 196485

End: 197489

Strand: Reverse

Name: yrbG [C]

Synonym: Paes_0189

Alternate gene names: 194333035

Gene position: 197489-196485 (Counterclockwise)

Preceding gene: 194333039

Following gene: 194333026

Centisome position: 7.86

GC content: 53.23

Gene sequence:

>1005_bases
ATGTTGCCTGATGTCATGAATCACATAGGCCTGTCCGGTAATATCGCCATCCTCGGCGTGAGCGGCCTTCTGCTCTTCAT
TGGGGCAGAATGGCTTATCCGGGGCAGTGTCGATCTGGCTGGAAAATTCGGCATCAAACCGTTCGTGATCGGTCTCACGG
TAGTGGCCTACGGCACATCTATGCCGGAGTTTGTCGTCAGCTTCTTCGCTCATGTCGTTGAAGATTCGGATAGCATTTCA
CTGGGCAACGTCATCGGCAGCAACATCACCAATATCGGTCTTATCCTCGGCCTCAGCGCCCTGATCTTCCCTATCCACAT
CGCATTTCAAAGCATTCGCAACCAGTCGCTGTTTCTGTTCGGCATCAGCATGATCGTCTATCTCCTCGCCCTTGACGGAA
CCATCTCCCGGGCGGAGGGAGGCGTGCTCTTCACGCTGCTCTGCGGCTACCTGTTCGTCATGTACCGTACCCCTGAAATT
GCTGAAGAATCATTTGAAGAGGCACCCGAAAGTCAGGATATACTGCCCCTTGCAACAAGCATCTCGCTTGTCGGTGCTGG
AAGTGTTCTGCTTTCAACAGGGGCGTGGTCTTTTGTCAAAAGCTCGGTATGGATTGCCGAACAGCTCAATATCCCTAAGC
TCTACATCGGGCTTTCTATCGTCGCTCTCGGAACCTCGCTGCCGGAGCTGGCGACATCGCTAGTAGGGGCTATCCGGAGA
GAGAGCGAGATCTCTGTCGGCAATCTTATCGGAAGCAATATCTTTAACATTCTCTTCGTGCTGGGAGGGGTCAGCATGAT
CAAACCCGTTTCGGTTATCGAGCCGCTCCTTGCCGATGCAGCAATCACCCCATCGTTTCCCCACATGCAGTTTCTGATCA
TGATCGCGTTCGGACTGCTCCTGCTCCCGATGAGTTTTCACCGCAATATCATCGGACGATGGTCGGGCTTCACCCTGCTA
TGCTGCTACGGATTGTTTTACTGGCAGCTCTTTAGCGCAGAGTGA

Upstream 100 bases:

>100_bases
CAGTTACAAGTATCGATATCGCCTTTAAAATTTATCATTGTAGCTTTATAATAAGAAACGAATTCTCATAAGACAACCTG
CCCCCCTATCTGAAAGAGCC

Downstream 100 bases:

>100_bases
TGACGTTCAGAGGAAAAGACCCGGAGCTTTGCGGGCAGGCTTCTTTTTGATCGTCAGCGCAGAAAGGCCAAGAATACTGA
GAAGAATATCGGGAGTGGGC

Product: CaCA family Na+/Ca+ antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLPDVMNHIGLSGNIAILGVSGLLLFIGAEWLIRGSVDLAGKFGIKPFVIGLTVVAYGTSMPEFVVSFFAHVVEDSDSIS
LGNVIGSNITNIGLILGLSALIFPIHIAFQSIRNQSLFLFGISMIVYLLALDGTISRAEGGVLFTLLCGYLFVMYRTPEI
AEESFEEAPESQDILPLATSISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRR
ESEISVGNLIGSNIFNILFVLGGVSMIKPVSVIEPLLADAAITPSFPHMQFLIMIAFGLLLLPMSFHRNIIGRWSGFTLL
CCYGLFYWQLFSAE

Sequences:

>Translated_334_residues
MLPDVMNHIGLSGNIAILGVSGLLLFIGAEWLIRGSVDLAGKFGIKPFVIGLTVVAYGTSMPEFVVSFFAHVVEDSDSIS
LGNVIGSNITNIGLILGLSALIFPIHIAFQSIRNQSLFLFGISMIVYLLALDGTISRAEGGVLFTLLCGYLFVMYRTPEI
AEESFEEAPESQDILPLATSISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRR
ESEISVGNLIGSNIFNILFVLGGVSMIKPVSVIEPLLADAAITPSFPHMQFLIMIAFGLLLLPMSFHRNIIGRWSGFTLL
CCYGLFYWQLFSAE
>Mature_334_residues
MLPDVMNHIGLSGNIAILGVSGLLLFIGAEWLIRGSVDLAGKFGIKPFVIGLTVVAYGTSMPEFVVSFFAHVVEDSDSIS
LGNVIGSNITNIGLILGLSALIFPIHIAFQSIRNQSLFLFGISMIVYLLALDGTISRAEGGVLFTLLCGYLFVMYRTPEI
AEESFEEAPESQDILPLATSISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRR
ESEISVGNLIGSNIFNILFVLGGVSMIKPVSVIEPLLADAAITPSFPHMQFLIMIAFGLLLLPMSFHRNIIGRWSGFTLL
CCYGLFYWQLFSAE

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=254, Percent_Identity=35.0393700787402, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 35900; Mature: 35900

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDVMNHIGLSGNIAILGVSGLLLFIGAEWLIRGSVDLAGKFGIKPFVIGLTVVAYGTS
CCCHHHHHCCCCCCEEEEEHHHHHHHHCCHHHEECCCCCCCCCCCCHHHHHHHHHHHCCC
MPEFVVSFFAHVVEDSDSISLGNVIGSNITNIGLILGLSALIFPIHIAFQSIRNQSLFLF
CHHHHHHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GISMIVYLLALDGTISRAEGGVLFTLLCGYLFVMYRTPEIAEESFEEAPESQDILPLATS
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHH
ISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRR
HHHHCCCHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ESEISVGNLIGSNIFNILFVLGGVSMIKPVSVIEPLLADAAITPSFPHMQFLIMIAFGLL
CCCCCHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LLPMSFHRNIIGRWSGFTLLCCYGLFYWQLFSAE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLPDVMNHIGLSGNIAILGVSGLLLFIGAEWLIRGSVDLAGKFGIKPFVIGLTVVAYGTS
CCCHHHHHCCCCCCEEEEEHHHHHHHHCCHHHEECCCCCCCCCCCCHHHHHHHHHHHCCC
MPEFVVSFFAHVVEDSDSISLGNVIGSNITNIGLILGLSALIFPIHIAFQSIRNQSLFLF
CHHHHHHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GISMIVYLLALDGTISRAEGGVLFTLLCGYLFVMYRTPEIAEESFEEAPESQDILPLATS
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHH
ISLVGAGSVLLSTGAWSFVKSSVWIAEQLNIPKLYIGLSIVALGTSLPELATSLVGAIRR
HHHHCCCHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ESEISVGNLIGSNIFNILFVLGGVSMIKPVSVIEPLLADAAITPSFPHMQFLIMIAFGLL
CCCCCHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LLPMSFHRNIIGRWSGFTLLCCYGLFYWQLFSAE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]