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The map label for this gene is infC

Identifier: 194333012

GI number: 194333012

Start: 172301

End: 172894

Strand: Reverse

Name: infC

Synonym: Paes_0166

Alternate gene names: 194333012

Gene position: 172894-172301 (Counterclockwise)

Preceding gene: 194333013

Following gene: 194333011

Centisome position: 6.88

GC content: 45.62

Gene sequence:

>594_bases
ATGAGAAAAAAGAGAAGCGCTCCTCAAAAGCCAAAACTAACCTACAGGGTCAATGAGCAGATCCGTGTTCCTGAGGTAAG
AGTTGTTTTCAAGGATGGTTCACAGGAAATCCTGAAAACCGGCGAAGCCAGAAAAATGGCTGAACAGGAGGGACTTGATC
TCATTGAAGTACAGCCTACGGCACAACCCCCTGTCTGCAAAATGGACAACTACGGTAAACTGCAGTACAAGCTGGATAAA
AATGAAAAGGACCGTAAGAAAAAGTCGAAACCCACAGAGTTAAAGGAGCTTCGCTTTCATCCAAATACGGACACACACGA
CTTCGACTTCAAGTCGGCGCACCTTGAAGAGTTTCTCCGCAAAGGCAACAGGGTCCGAGCCACCATTGTCTTTCTCGGTC
GCTCTATTATCTACAAAGATAAAGGGTTCGAGCTCGTCGAGCGCCTTAAGGAACGCCTGAGCAACGTGAGCAACCCCGAG
GGTGAAGCAAAATTCGAAGGAAAACGGCTTTTTATCTATTTCGAACCCGATAAAAAGAAAATCGAAATCTTCGAAAGACA
GTTAGCAAAAATGAAACCGGAAGAAAAGCCGTAA

Upstream 100 bases:

>100_bases
AGAAGAACTGAAAGAAAAATTAGCTAAGGAAATTAACGACAAATCCTGAGACCGCAGCAAGAATTGTTCTGATAGCGGCC
GTCACACAAATCCAGACCAT

Downstream 100 bases:

>100_bases
CAATCATTACCGATAACAAAACGATACGATCATGCCAAAAATGAAATCACACCGCGGCGCATGCAAGCGGTTTAAAAAGA
CTGCTTCAGGCAAAGTAAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MRKKRSAPQKPKLTYRVNEQIRVPEVRVVFKDGSQEILKTGEARKMAEQEGLDLIEVQPTAQPPVCKMDNYGKLQYKLDK
NEKDRKKKSKPTELKELRFHPNTDTHDFDFKSAHLEEFLRKGNRVRATIVFLGRSIIYKDKGFELVERLKERLSNVSNPE
GEAKFEGKRLFIYFEPDKKKIEIFERQLAKMKPEEKP

Sequences:

>Translated_197_residues
MRKKRSAPQKPKLTYRVNEQIRVPEVRVVFKDGSQEILKTGEARKMAEQEGLDLIEVQPTAQPPVCKMDNYGKLQYKLDK
NEKDRKKKSKPTELKELRFHPNTDTHDFDFKSAHLEEFLRKGNRVRATIVFLGRSIIYKDKGFELVERLKERLSNVSNPE
GEAKFEGKRLFIYFEPDKKKIEIFERQLAKMKPEEKP
>Mature_197_residues
MRKKRSAPQKPKLTYRVNEQIRVPEVRVVFKDGSQEILKTGEARKMAEQEGLDLIEVQPTAQPPVCKMDNYGKLQYKLDK
NEKDRKKKSKPTELKELRFHPNTDTHDFDFKSAHLEEFLRKGNRVRATIVFLGRSIIYKDKGFELVERLKERLSNVSNPE
GEAKFEGKRLFIYFEPDKKKIEIFERQLAKMKPEEKP

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=37.125748502994, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_PROA2 (B4S3D1)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002014872.1
- ProteinModelPortal:   B4S3D1
- GeneID:   6460662
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_0166
- HOGENOM:   HBG744268
- OMA:   KQMKFRL
- ProtClustDB:   PRK00028
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 23265; Mature: 23265

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKRSAPQKPKLTYRVNEQIRVPEVRVVFKDGSQEILKTGEARKMAEQEGLDLIEVQPT
CCCCCCCCCCCCEEEEECCEEECCEEEEEEECCCHHHHHCCHHHHHHHHCCCEEEEECCC
AQPPVCKMDNYGKLQYKLDKNEKDRKKKSKPTELKELRFHPNTDTHDFDFKSAHLEEFLR
CCCCEECCCCCCEEEEEECCCHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHH
KGNRVRATIVFLGRSIIYKDKGFELVERLKERLSNVSNPEGEAKFEGKRLFIYFEPDKKK
CCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCHH
IEIFERQLAKMKPEEKP
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKKRSAPQKPKLTYRVNEQIRVPEVRVVFKDGSQEILKTGEARKMAEQEGLDLIEVQPT
CCCCCCCCCCCCEEEEECCEEECCEEEEEEECCCHHHHHCCHHHHHHHHCCCEEEEECCC
AQPPVCKMDNYGKLQYKLDKNEKDRKKKSKPTELKELRFHPNTDTHDFDFKSAHLEEFLR
CCCCEECCCCCCEEEEEECCCHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHH
KGNRVRATIVFLGRSIIYKDKGFELVERLKERLSNVSNPEGEAKFEGKRLFIYFEPDKKK
CCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCHH
IEIFERQLAKMKPEEKP
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA