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The map label for this gene is plsC [H]

Identifier: 193213551

GI number: 193213551

Start: 2112496

End: 2113209

Strand: Direct

Name: plsC [H]

Synonym: Cpar_1912

Alternate gene names: 193213551

Gene position: 2112496-2113209 (Clockwise)

Preceding gene: 193213550

Following gene: 193213566

Centisome position: 92.28

GC content: 55.32

Gene sequence:

>714_bases
ATGAATCTCCAGACGATTCTCTTTTTCCTGGTGATCATCCCGGTCATGTTCTTCGGGATGCTCTTTGCGCTCATCCTGAA
CCTGTTCGATCCGACCGGTGACCGGTTTCATACCATGGCCGCCTGGTGGGGACGCTTTGCCGCAAAGCTGCTCGGCATTA
CCGTCACGGTGGAGGGAGAGGAGAACTACAACCCCGACAAGAACTACCTGGTCGTCAGCAACCATGCCGGCATGGCCGAC
ATTCCACTGATTCTTGGGGCGATAAAACTCAATCTGAGGTTTGTAGCCAAGGAGGAGCTTGGCAAGGTGCCGATATTCGG
CCATGCGCTGAAATCGGGCGGCTATGTTTTCATCAAGCGTGGCCAGAACCGGGAGGCGCTGCAAAGCATGCTGAAAGCGG
CCGACACGCTCAAAGCCGGGCGTTCGATTCACATCTTCCCCGAAGGCACGCGCTCCAAAACAGGCGACATCCTGCCCTTC
AAGCGGGGTGCATTCATCATTGCCGAGAAAGCGAAAGTGCCCGTGCTGCCCGTAACCATTGTCGGCAGCAACCTCATCAC
TCCGAAAAAGAGCCTGAAAATCAACCACGGCACGGTGCGCATGATCATTAGCAAACCGATCGATCCCGACCAGCACGCCA
AAGCCGAAGAGTTGATGAAGGAGAGTTACAGAATCATCAGCGGCAATCTGGAGCAAGTGAACAACGCCGCGTAA

Upstream 100 bases:

>100_bases
ACAAGCCGAAACAGGCTACGCTGATCGGTAACAGATACGAAGATCTTGCCGGATTCCTTGGCAATCTCGACCGGTAAGCA
ACCAGACCCCGACAGAACCC

Downstream 100 bases:

>100_bases
GAGTTGAACCTGTAGCGGCAAGTTCGCAAACCACCGCTACAGCTCACCGAGGGCGACCGGGCGGCCACCCATTGCTAAAC
GTTATCCCAACTGCTTGTAG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNLQTILFFLVIIPVMFFGMLFALILNLFDPTGDRFHTMAAWWGRFAAKLLGITVTVEGEENYNPDKNYLVVSNHAGMAD
IPLILGAIKLNLRFVAKEELGKVPIFGHALKSGGYVFIKRGQNREALQSMLKAADTLKAGRSIHIFPEGTRSKTGDILPF
KRGAFIIAEKAKVPVLPVTIVGSNLITPKKSLKINHGTVRMIISKPIDPDQHAKAEELMKESYRIISGNLEQVNNAA

Sequences:

>Translated_237_residues
MNLQTILFFLVIIPVMFFGMLFALILNLFDPTGDRFHTMAAWWGRFAAKLLGITVTVEGEENYNPDKNYLVVSNHAGMAD
IPLILGAIKLNLRFVAKEELGKVPIFGHALKSGGYVFIKRGQNREALQSMLKAADTLKAGRSIHIFPEGTRSKTGDILPF
KRGAFIIAEKAKVPVLPVTIVGSNLITPKKSLKINHGTVRMIISKPIDPDQHAKAEELMKESYRIISGNLEQVNNAA
>Mature_237_residues
MNLQTILFFLVIIPVMFFGMLFALILNLFDPTGDRFHTMAAWWGRFAAKLLGITVTVEGEENYNPDKNYLVVSNHAGMAD
IPLILGAIKLNLRFVAKEELGKVPIFGHALKSGGYVFIKRGQNREALQSMLKAADTLKAGRSIHIFPEGTRSKTGDILPF
KRGAFIIAEKAKVPVLPVTIVGSNLITPKKSLKINHGTVRMIISKPIDPDQHAKAEELMKESYRIISGNLEQVNNAA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=159, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI15100175, Length=159, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI6041665, Length=190, Percent_Identity=27.3684210526316, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1789395, Length=236, Percent_Identity=28.3898305084746, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17568319, Length=188, Percent_Identity=23.4042553191489, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564032, Length=187, Percent_Identity=28.3422459893048, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320151, Length=216, Percent_Identity=30.5555555555556, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281364648, Length=228, Percent_Identity=25.8771929824561, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24582856, Length=228, Percent_Identity=25.8771929824561, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24582854, Length=228, Percent_Identity=25.8771929824561, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641614, Length=223, Percent_Identity=26.9058295964126, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641612, Length=223, Percent_Identity=26.9058295964126, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26211; Mature: 26211

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQTILFFLVIIPVMFFGMLFALILNLFDPTGDRFHTMAAWWGRFAAKLLGITVTVEGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEEEECC
ENYNPDKNYLVVSNHAGMADIPLILGAIKLNLRFVAKEELGKVPIFGHALKSGGYVFIKR
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEHHHCCCCCEEHHHHCCCCEEEEEE
GQNREALQSMLKAADTLKAGRSIHIFPEGTRSKTGDILPFKRGAFIIAEKAKVPVLPVTI
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCEEEEEECCCCCEEEEEE
VGSNLITPKKSLKINHGTVRMIISKPIDPDQHAKAEELMKESYRIISGNLEQVNNAA
ECCCCCCCHHHEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MNLQTILFFLVIIPVMFFGMLFALILNLFDPTGDRFHTMAAWWGRFAAKLLGITVTVEGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEEEECC
ENYNPDKNYLVVSNHAGMADIPLILGAIKLNLRFVAKEELGKVPIFGHALKSGGYVFIKR
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEHHHCCCCCEEHHHHCCCCEEEEEE
GQNREALQSMLKAADTLKAGRSIHIFPEGTRSKTGDILPFKRGAFIIAEKAKVPVLPVTI
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCEEEEEECCCCCEEEEEE
VGSNLITPKKSLKINHGTVRMIISKPIDPDQHAKAEELMKESYRIISGNLEQVNNAA
ECCCCCCCHHHEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]