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The map label for this gene is efp

Identifier: 193213518

GI number: 193213518

Start: 2068306

End: 2068872

Strand: Direct

Name: efp

Synonym: Cpar_1879

Alternate gene names: 193213518

Gene position: 2068306-2068872 (Clockwise)

Preceding gene: 193213515

Following gene: 193213519

Centisome position: 90.35

GC content: 54.85

Gene sequence:

>567_bases
ATGGTTTCAATAAGCAACGTCTCAAAAGGGGCCATCATCCGCTGGAAGGGTGAACCCCACAGCATCGAAAGCCTTGTGCA
TCGCACGCCAGGCAACCTTCGCGCCTTCTATCAGGCCAGCATGAAAAACCTCAAGACCGGCCGCAACGTCGAGTACCGCT
TCAGCGCCACCGAGCAGGTCGATGTCATCGTCACCGAGAGAAAGAAATACCAGTACCTCTATCGAGACGGTGAAGATTAT
GTCATGATGGATACCGAAACCTTCGACCAGATCAACGTGCCGGAAGTGGCCATCGGTTCTGCATCACGCTTCATCAAGGA
TGCCGTGATGGTCGATATCGTGTTTGCCGATGACGGCTCGATTCTCGAAGTTGAACTGCCGACCTTCGTTGAACTGGAGG
TTACCGAAACCAACCCTGCAAGCAAGGATGACCGCGCCACCAGCGGCACCAAGCCGGCCATCGTCGAAACCGGTGCCGAG
GTGAACGTGCCCATGTTTATCCAGACCGGCAGCATCATCCGCATCGACACCCGGAGCGGCGAGTACATGGATAGAGTTAA
AAAGTGA

Upstream 100 bases:

>100_bases
TGGTATTGAACGCCTGCGGTGTTATATTCATTTTCTTTTTTCTTTTAACCATTGTTTTGCAGGCACCGCTCAGAAATCGC
CTGTTTCACCTAATCACGTC

Downstream 100 bases:

>100_bases
TTAACTTGCCAGTCATAACCGAATTGCGCGTAAAAATCTTAAGACCACACTCATGAACCTCAAGGAAATCCAGCAGCTTA
TCGAGATTGTCAACGGTTCG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MVSISNVSKGAIIRWKGEPHSIESLVHRTPGNLRAFYQASMKNLKTGRNVEYRFSATEQVDVIVTERKKYQYLYRDGEDY
VMMDTETFDQINVPEVAIGSASRFIKDAVMVDIVFADDGSILEVELPTFVELEVTETNPASKDDRATSGTKPAIVETGAE
VNVPMFIQTGSIIRIDTRSGEYMDRVKK

Sequences:

>Translated_188_residues
MVSISNVSKGAIIRWKGEPHSIESLVHRTPGNLRAFYQASMKNLKTGRNVEYRFSATEQVDVIVTERKKYQYLYRDGEDY
VMMDTETFDQINVPEVAIGSASRFIKDAVMVDIVFADDGSILEVELPTFVELEVTETNPASKDDRATSGTKPAIVETGAE
VNVPMFIQTGSIIRIDTRSGEYMDRVKK
>Mature_188_residues
MVSISNVSKGAIIRWKGEPHSIESLVHRTPGNLRAFYQASMKNLKTGRNVEYRFSATEQVDVIVTERKKYQYLYRDGEDY
VMMDTETFDQINVPEVAIGSASRFIKDAVMVDIVFADDGSILEVELPTFVELEVTETNPASKDDRATSGTKPAIVETGAE
VNVPMFIQTGSIIRIDTRSGEYMDRVKK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=178, Percent_Identity=39.8876404494382, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=30.3191489361702, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_CHLP8 (B3QQR8)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999471.1
- GeneID:   6420826
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1879
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21122; Mature: 21122

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSISNVSKGAIIRWKGEPHSIESLVHRTPGNLRAFYQASMKNLKTGRNVEYRFSATEQV
CEECCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEE
DVIVTERKKYQYLYRDGEDYVMMDTETFDQINVPEVAIGSASRFIKDAVMVDIVFADDGS
EEEEECCCEEEEEEECCCCEEEEECCCCCCCCCCCEEECCHHHHHHCEEEEEEEEECCCC
ILEVELPTFVELEVTETNPASKDDRATSGTKPAIVETGAEVNVPMFIQTGSIIRIDTRSG
EEEEECCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCEEEEECCCC
EYMDRVKK
HHHHHHCC
>Mature Secondary Structure
MVSISNVSKGAIIRWKGEPHSIESLVHRTPGNLRAFYQASMKNLKTGRNVEYRFSATEQV
CEECCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEE
DVIVTERKKYQYLYRDGEDYVMMDTETFDQINVPEVAIGSASRFIKDAVMVDIVFADDGS
EEEEECCCEEEEEEECCCCEEEEECCCCCCCCCCCEEECCHHHHHHCEEEEEEEEECCCC
ILEVELPTFVELEVTETNPASKDDRATSGTKPAIVETGAEVNVPMFIQTGSIIRIDTRSG
EEEEECCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCEEEEECCCC
EYMDRVKK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA