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The map label for this gene is fbp

Identifier: 193213323

GI number: 193213323

Start: 1840115

End: 1841116

Strand: Direct

Name: fbp

Synonym: Cpar_1682

Alternate gene names: 193213323

Gene position: 1840115-1841116 (Clockwise)

Preceding gene: 193213321

Following gene: 193213325

Centisome position: 80.38

GC content: 59.28

Gene sequence:

>1002_bases
ATGAACAAGCTCACCACCATTGAAAGCCATTTTCTCCAGCAGCAGAAGCTCTATCCCGAAATCAACAGCGAGGTGACCGG
CCTTCTGAACGATGTCGCCTTTGCCGCAAAACTGGTACGGCGCGAAGTCGTGCGCGCCGGACTTGCCGACATTCTCGGCC
TTGCCGGTTCCACCAACGTGCAGGGCGAGGAGGTCAAAAAGCTCGATCTGTTCGCCAACGAACGGCTCATCAACGCCATC
GGCCAGCACGGGCGCTTCGCCATTATGGGCTCCGAGGAGAACGAAGAGACCATCACGCCGCCGAAGTTCGAGTCGGGCGA
ATACGTTCTGCTTTTCGACCCGCTCGACGGCTCATCGAACATCGACGTGAATGTCAGCGTCGGCACCATCTTTTCGATCT
ACCGGCTCAAGAGCGACAACCCTTCGCAAGCGAGCATCGAGGACTGCCTGCAGAAAGGCGCTGATCAGGTGGCTGCCGGC
TACGTCATTTACGGCTCGTCGGTCATGCTGGTCTACACCACCGGCCACGGCGTGCATGGTTTCACCTTCGACCAGACCGT
CGGCGAATTCCTGCTCTCGCACGAGAACATCACCACCCCGGAGCACGGTAAATACTACTCGGTTAACGAGGGCTCATGGA
ATGAGTTTCACGACGGCACGAAGCTCTTTCTGGACTACCTCAAGGAGGAGGACAAGGCAACCGGCCGCCCCTACAGCACG
CGCTACATCGGCTCGTTCGTGGCCGACTTCCACCGCAACCTGCTGACCGGCGGCGTGTTCATCTACCCGGCAACGAAGAA
GCACAAAAATGGCAAGCTGCGCCTGATGTACGAAGCCAACCCGATGGCCTTCATCTGCGAGCAGGCCGGAGGTCGCGCCA
CCGACGGACACCGCCGGATTCTCGACATCGAGCCGGTAGAGCTGCACCAGCGCACGCCGCTCTACATCGGCAGCAAGAAC
GACGTGCTCATAGCCGAAGAGTTCGAGCAGGACAAGCGATGA

Upstream 100 bases:

>100_bases
TTAATCATCTATCCGGACAAGCAGCGCCAGCCTCTGCATTTTCAGCGCCGGATCCCGCGGTCTCTTCGGCCGTCATTCAA
TCATTCTGAACGATTTTGTG

Downstream 100 bases:

>100_bases
TTTTTATTAGACTTTGCAGACAACAAAACCCCAACCAAATGGCTGGGGTTTTTGTTTTTCAATTTCGATAATAGGGCAAC
CTCATCCTGACCTGATTACT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNKLTTIESHFLQQQKLYPEINSEVTGLLNDVAFAAKLVRREVVRAGLADILGLAGSTNVQGEEVKKLDLFANERLINAI
GQHGRFAIMGSEENEETITPPKFESGEYVLLFDPLDGSSNIDVNVSVGTIFSIYRLKSDNPSQASIEDCLQKGADQVAAG
YVIYGSSVMLVYTTGHGVHGFTFDQTVGEFLLSHENITTPEHGKYYSVNEGSWNEFHDGTKLFLDYLKEEDKATGRPYST
RYIGSFVADFHRNLLTGGVFIYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGHRRILDIEPVELHQRTPLYIGSKN
DVLIAEEFEQDKR

Sequences:

>Translated_333_residues
MNKLTTIESHFLQQQKLYPEINSEVTGLLNDVAFAAKLVRREVVRAGLADILGLAGSTNVQGEEVKKLDLFANERLINAI
GQHGRFAIMGSEENEETITPPKFESGEYVLLFDPLDGSSNIDVNVSVGTIFSIYRLKSDNPSQASIEDCLQKGADQVAAG
YVIYGSSVMLVYTTGHGVHGFTFDQTVGEFLLSHENITTPEHGKYYSVNEGSWNEFHDGTKLFLDYLKEEDKATGRPYST
RYIGSFVADFHRNLLTGGVFIYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGHRRILDIEPVELHQRTPLYIGSKN
DVLIAEEFEQDKR
>Mature_333_residues
MNKLTTIESHFLQQQKLYPEINSEVTGLLNDVAFAAKLVRREVVRAGLADILGLAGSTNVQGEEVKKLDLFANERLINAI
GQHGRFAIMGSEENEETITPPKFESGEYVLLFDPLDGSSNIDVNVSVGTIFSIYRLKSDNPSQASIEDCLQKGADQVAAG
YVIYGSSVMLVYTTGHGVHGFTFDQTVGEFLLSHENITTPEHGKYYSVNEGSWNEFHDGTKLFLDYLKEEDKATGRPYST
RYIGSFVADFHRNLLTGGVFIYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGHRRILDIEPVELHQRTPLYIGSKN
DVLIAEEFEQDKR

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=316, Percent_Identity=45.253164556962, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI16579888, Length=316, Percent_Identity=45.253164556962, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI22907028, Length=300, Percent_Identity=47.3333333333333, Blast_Score=270, Evalue=1e-72,
Organism=Escherichia coli, GI1790679, Length=325, Percent_Identity=52.6153846153846, Blast_Score=351, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI17508131, Length=325, Percent_Identity=47.6923076923077, Blast_Score=317, Evalue=8e-87,
Organism=Saccharomyces cerevisiae, GI6323409, Length=321, Percent_Identity=43.3021806853583, Blast_Score=270, Evalue=3e-73,
Organism=Drosophila melanogaster, GI45550998, Length=317, Percent_Identity=48.5804416403785, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI19921562, Length=317, Percent_Identity=48.5804416403785, Blast_Score=300, Evalue=7e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_CHLP8 (B3QQ73)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999276.1
- GeneID:   6420623
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1682
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- ProtClustDB:   PRK09293
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 37164; Mature: 37164

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00124 FBPASE

Important sites: BINDING 209-209 BINDING 242-242 BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLTTIESHFLQQQKLYPEINSEVTGLLNDVAFAAKLVRREVVRAGLADILGLAGSTNV
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGEEVKKLDLFANERLINAIGQHGRFAIMGSEENEETITPPKFESGEYVLLFDPLDGSSN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
IDVNVSVGTIFSIYRLKSDNPSQASIEDCLQKGADQVAAGYVIYGSSVMLVYTTGHGVHG
EEEEEEHHHEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCEEEECCCEEEEEEECCCCCC
FTFDQTVGEFLLSHENITTPEHGKYYSVNEGSWNEFHDGTKLFLDYLKEEDKATGRPYST
EEHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCH
RYIGSFVADFHRNLLTGGVFIYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGHRRI
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEE
LDIEPVELHQRTPLYIGSKNDVLIAEEFEQDKR
EECCCHHHCCCCCEEECCCCCEEEEECCCCCCC
>Mature Secondary Structure
MNKLTTIESHFLQQQKLYPEINSEVTGLLNDVAFAAKLVRREVVRAGLADILGLAGSTNV
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGEEVKKLDLFANERLINAIGQHGRFAIMGSEENEETITPPKFESGEYVLLFDPLDGSSN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
IDVNVSVGTIFSIYRLKSDNPSQASIEDCLQKGADQVAAGYVIYGSSVMLVYTTGHGVHG
EEEEEEHHHEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCEEEECCCEEEEEEECCCCCC
FTFDQTVGEFLLSHENITTPEHGKYYSVNEGSWNEFHDGTKLFLDYLKEEDKATGRPYST
EEHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCH
RYIGSFVADFHRNLLTGGVFIYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGHRRI
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEE
LDIEPVELHQRTPLYIGSKNDVLIAEEFEQDKR
EECCCHHHCCCCCEEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA