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The map label for this gene is pkn1 [H]

Identifier: 193213066

GI number: 193213066

Start: 1551267

End: 1552055

Strand: Direct

Name: pkn1 [H]

Synonym: Cpar_1419

Alternate gene names: 193213066

Gene position: 1551267-1552055 (Clockwise)

Preceding gene: 193213065

Following gene: 193213067

Centisome position: 67.76

GC content: 64.01

Gene sequence:

>789_bases
ATGAATTTGAACGACACCCTTTCCGAACTCAGAAGCCGCGCGATACGCCCGTCCGATGATGCGCTGCCGCCGGTCATCGT
CAACGAGCGGGATGGCTCCCCTATGGTACTCGTGCCCGCGGGCAAGTTCACGATGGGCGACGACCTCGACCGCGAAAGCC
CGCAGCGGAGCGTGCAACTCGAAGCGTTCTACATCTCGGTCTATCCGGTCACCAACCGCCAGTACCGCGCCTTCGTCGAA
GCCACCGGCCACCAGCCGCCCAACATCGGCGCTCGGATCGACTCGCTCTCCTTCTGGCGCGAAGAGGGGTGCCCCGCAGA
GTTCGACGACTACCCGGTCGTCCTCATCAGTTGGGACGACGCGGACGCCTACGCCAAATGGGCGGGATGCCGCCTGCCCA
ACGAAGCCGAGTGGGAAAAAGCCGCGCGCGGGCCGGAAGGGTTGCTCTACCCGTGGGGCGACAAATGGGACGAAAACAAC
TGCCGGAACCGCAACAACAAAGGCGAAGAGTCCGTCGCTCCGGTCTATTCGTACCCCGAAGGGGTCTCCGGCTACGGCAC
CTGGAACCAGAGCGGCAACATCATGGAGTGGTGCTCGATCTGGGAAGGCGAGGGCGATTCCGGCAACGCCACCGACGGCG
ACGAAGCCCTCCGCCAGGAACGAGGAGGCTGCTGGCGCTACCCCGACAAATTCGCCTTCCGCGCCTCGCAACGTTCGTTC
GTGGTGCCGAAAGCGGTGAATGATTTCCGGGGGTTTCGGCTGGTGTTGCCGGTGAAGGCGGGGATGTGA

Upstream 100 bases:

>100_bases
AGCCGGTGATCGACGGCCTGCGCGAGATGGTCAAAAACGGCCAGGCCCGCAACGCCTCCGCCGAACTAGGCGCGGCGGCT
TCACAACAATCGGAGCTACG

Downstream 100 bases:

>100_bases
GAGGGGTTAGTTTGTGGGTGGATTTGCAGTAAATTGTTTTTTTTGAATGAAGGGTAATTGCGGGCATCTTATGCGGACAC
GAATCAAGAGTCCGCGTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNLNDTLSELRSRAIRPSDDALPPVIVNERDGSPMVLVPAGKFTMGDDLDRESPQRSVQLEAFYISVYPVTNRQYRAFVE
ATGHQPPNIGARIDSLSFWREEGCPAEFDDYPVVLISWDDADAYAKWAGCRLPNEAEWEKAARGPEGLLYPWGDKWDENN
CRNRNNKGEESVAPVYSYPEGVSGYGTWNQSGNIMEWCSIWEGEGDSGNATDGDEALRQERGGCWRYPDKFAFRASQRSF
VVPKAVNDFRGFRLVLPVKAGM

Sequences:

>Translated_262_residues
MNLNDTLSELRSRAIRPSDDALPPVIVNERDGSPMVLVPAGKFTMGDDLDRESPQRSVQLEAFYISVYPVTNRQYRAFVE
ATGHQPPNIGARIDSLSFWREEGCPAEFDDYPVVLISWDDADAYAKWAGCRLPNEAEWEKAARGPEGLLYPWGDKWDENN
CRNRNNKGEESVAPVYSYPEGVSGYGTWNQSGNIMEWCSIWEGEGDSGNATDGDEALRQERGGCWRYPDKFAFRASQRSF
VVPKAVNDFRGFRLVLPVKAGM
>Mature_262_residues
MNLNDTLSELRSRAIRPSDDALPPVIVNERDGSPMVLVPAGKFTMGDDLDRESPQRSVQLEAFYISVYPVTNRQYRAFVE
ATGHQPPNIGARIDSLSFWREEGCPAEFDDYPVVLISWDDADAYAKWAGCRLPNEAEWEKAARGPEGLLYPWGDKWDENN
CRNRNNKGEESVAPVYSYPEGVSGYGTWNQSGNIMEWCSIWEGEGDSGNATDGDEALRQERGGCWRYPDKFAFRASQRSF
VVPKAVNDFRGFRLVLPVKAGM

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=257, Percent_Identity=33.852140077821, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI38202250, Length=282, Percent_Identity=31.5602836879433, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI257470977, Length=275, Percent_Identity=32.7272727272727, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI194248087, Length=201, Percent_Identity=31.3432835820896, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI194248088, Length=213, Percent_Identity=30.5164319248826, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI194248090, Length=193, Percent_Identity=30.0518134715026, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI226437577, Length=117, Percent_Identity=36.7521367521368, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130397, Length=252, Percent_Identity=30.5555555555556, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 29502; Mature: 29502

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNDTLSELRSRAIRPSDDALPPVIVNERDGSPMVLVPAGKFTMGDDLDRESPQRSVQL
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
EAFYISVYPVTNRQYRAFVEATGHQPPNIGARIDSLSFWREEGCPAEFDDYPVVLISWDD
EEEEEEEEEECCCCEEEEEEECCCCCCCCCCEECHHHHHHHCCCCCCCCCCCEEEEEECC
ADAYAKWAGCRLPNEAEWEKAARGPEGLLYPWGDKWDENNCRNRNNKGEESVAPVYSYPE
CHHHHHHHCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GVSGYGTWNQSGNIMEWCSIWEGEGDSGNATDGDEALRQERGGCWRYPDKFAFRASQRSF
CCCCCCCCCCCCCEEHHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHEECCCCCE
VVPKAVNDFRGFRLVLPVKAGM
ECCHHHHCCCCEEEEEEECCCC
>Mature Secondary Structure
MNLNDTLSELRSRAIRPSDDALPPVIVNERDGSPMVLVPAGKFTMGDDLDRESPQRSVQL
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
EAFYISVYPVTNRQYRAFVEATGHQPPNIGARIDSLSFWREEGCPAEFDDYPVVLISWDD
EEEEEEEEEECCCCEEEEEEECCCCCCCCCCEECHHHHHHHCCCCCCCCCCCEEEEEECC
ADAYAKWAGCRLPNEAEWEKAARGPEGLLYPWGDKWDENNCRNRNNKGEESVAPVYSYPE
CHHHHHHHCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GVSGYGTWNQSGNIMEWCSIWEGEGDSGNATDGDEALRQERGGCWRYPDKFAFRASQRSF
CCCCCCCCCCCCCEEHHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHEECCCCCE
VVPKAVNDFRGFRLVLPVKAGM
ECCHHHHCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]