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The map label for this gene is nrfD [H]

Identifier: 193213038

GI number: 193213038

Start: 1518192

End: 1519115

Strand: Direct

Name: nrfD [H]

Synonym: Cpar_1390

Alternate gene names: 193213038

Gene position: 1518192-1519115 (Clockwise)

Preceding gene: 193213037

Following gene: 193213039

Centisome position: 66.32

GC content: 56.82

Gene sequence:

>924_bases
ATGACGTTTGTACATCAGGAAGTATGGCACTGGCAGATTGCCACCTACCTTTTTCTTGGAGGTCTGGGAGGCGCTACCTT
TGCCATCAGCGCGGTGCTTCACCTCTTCGAGGGATGCGACCGCAAAATGCTTTCCGTGGCCGTCATGTCATCGATCTTCT
TTTTGGTGCTTGGCACCATCTTCCTGCTCGCGGACATGCTCCAGCCACTCAAGGCTATCTACGCCCTCACCAATCCCAAA
TCGTGGATTTTCTGGGGCGTCATCTTTATCAACTTCTATTTTGTATCGGCTATCGCGTATGTGATACCACTGCTTGAGGT
GTGGCCGAAACTCGAGCCGATCATCCGGAAAATTCCCGAGTCGATCCTCGGCCTTCTGGAGCGCTTTAACAAGCTGGCCG
CGCTGGCCGGTTCGGCGGCAGGCTTTCTGGTGGCCATTTACACCGGCCTGTTGATTTCAGCGGCTCCGGCCATCAACTTC
TGGAACACACCGGCCCTGCCGCTGCTGTTCGTGATCTCGGGATTCTCGACCGGCGCCGCCTTCCTCTTGCTGCTCTCGAC
CTTCTCGCAGAACGAGTTCGCGCACAAAATCACCTCCAAGCTGGAACAGCTCGACGCCGTCCTGATCGTCACCGAGCTGA
TCATTCTCGGAGCCTACTTCAACTTCGCAATGTTCCTGCCCACCGGCGCTCGCGCTTCGGCCGAGTACCTGTTCCAGAGC
CCGCTCTTTATCGGCGGCTTCTTCGTGGCAGGCCTCATCGTGCCGTTGCTCATCGAGACCTACAGCATCTTCTTCGCCGG
GCACGGGCACGAAGAAAAGAAGTCCGCACTGCCGGTTCTGATGGCCAGCTCGCTGGTGCTCTTCGGCGGTTTCCTCTTGC
GTATCTACGTTCTGAAAGCCGGTATGTTCCAGTTCCCCTGGTAA

Upstream 100 bases:

>100_bases
CACAAGCTTGCCACCAGCGGCAAGGCGCAGGCGCTGAACCAGGGGCTCGGCACCTCTCCGAAAGTATTTTACATCCCATC
ATAGCAAGGAGGCCCTCATT

Downstream 100 bases:

>100_bases
CCTACGGCTTGAAAGCAAAAACCTCGACGCCCGGTCTCCGCTTGTCGGATCACCGGGCGTCCATCGTTTATCCACTATGA
GTTCACCATTGCAGAAGGCG

Product: polysulfide reductase NrfD

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIFFLVLGTIFLLADMLQPLKAIYALTNPK
SWIFWGVIFINFYFVSAIAYVIPLLEVWPKLEPIIRKIPESILGLLERFNKLAALAGSAAGFLVAIYTGLLISAAPAINF
WNTPALPLLFVISGFSTGAAFLLLLSTFSQNEFAHKITSKLEQLDAVLIVTELIILGAYFNFAMFLPTGARASAEYLFQS
PLFIGGFFVAGLIVPLLIETYSIFFAGHGHEEKKSALPVLMASSLVLFGGFLLRIYVLKAGMFQFPW

Sequences:

>Translated_307_residues
MTFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIFFLVLGTIFLLADMLQPLKAIYALTNPK
SWIFWGVIFINFYFVSAIAYVIPLLEVWPKLEPIIRKIPESILGLLERFNKLAALAGSAAGFLVAIYTGLLISAAPAINF
WNTPALPLLFVISGFSTGAAFLLLLSTFSQNEFAHKITSKLEQLDAVLIVTELIILGAYFNFAMFLPTGARASAEYLFQS
PLFIGGFFVAGLIVPLLIETYSIFFAGHGHEEKKSALPVLMASSLVLFGGFLLRIYVLKAGMFQFPW
>Mature_306_residues
TFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIFFLVLGTIFLLADMLQPLKAIYALTNPKS
WIFWGVIFINFYFVSAIAYVIPLLEVWPKLEPIIRKIPESILGLLERFNKLAALAGSAAGFLVAIYTGLLISAAPAINFW
NTPALPLLFVISGFSTGAAFLLLLSTFSQNEFAHKITSKLEQLDAVLIVTELIILGAYFNFAMFLPTGARASAEYLFQSP
LFIGGFFVAGLIVPLLIETYSIFFAGHGHEEKKSALPVLMASSLVLFGGFLLRIYVLKAGMFQFPW

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: COG3301

COG function: function code P; Formate-dependent nitrite reductase, membrane component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

Organism=Escherichia coli, GI1790509, Length=327, Percent_Identity=27.217125382263, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017566
- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 33883; Mature: 33752

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00318 HMG_COA_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIFFLVLGTI
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FLLADMLQPLKAIYALTNPKSWIFWGVIFINFYFVSAIAYVIPLLEVWPKLEPIIRKIPE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILGLLERFNKLAALAGSAAGFLVAIYTGLLISAAPAINFWNTPALPLLFVISGFSTGAA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHH
FLLLLSTFSQNEFAHKITSKLEQLDAVLIVTELIILGAYFNFAMFLPTGARASAEYLFQS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
PLFIGGFFVAGLIVPLLIETYSIFFAGHGHEEKKSALPVLMASSLVLFGGFLLRIYVLKA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMFQFPW
CCCCCCC
>Mature Secondary Structure 
TFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIFFLVLGTI
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8057835; 8265357; 9278503 [H]